Extended Data Fig. 2: Univariate associations between cognitive assessments and brain MRI IDPs. | Nature Cardiovascular Research

Extended Data Fig. 2: Univariate associations between cognitive assessments and brain MRI IDPs.

From: Large-scale identification of protein biomarkers and therapeutic targets in heart and brain disease

Extended Data Fig. 2: Univariate associations between cognitive assessments and brain MRI IDPs.

Manhattan plot of two-sided Pearson correlation results between three cognitive assessment domains and 2,222 brain MRI imaging-derived phenotypes (BMR IDPs). The x-axis indicates BMR IDP categories and the y-axis shows −log10(P). The horizontal blue line indicates the Bonferroni-corrected significance threshold (P < 2.81×10⁻⁶); Black outlines denote associations that remain significant after false discovery rate (FDR) correction.

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