Fig. 1: Envisioned medical potential of MRI-guided acoustic trapping, our hardware architecture, and demonstrated functionalities. | Communications Engineering

Fig. 1: Envisioned medical potential of MRI-guided acoustic trapping, our hardware architecture, and demonstrated functionalities.

From: Machine learning-facilitated real-time acoustic trapping in time-varying multi-medium environments toward magnetic resonance imaging-guided microbubble manipulation

Fig. 1: Envisioned medical potential of MRI-guided acoustic trapping, our hardware architecture, and demonstrated functionalities.The alternative text for this image may have been generated using AI.

a Proof-of-concept of MRI-guided acoustic trapping for tumor treatment. MRI visualizes the acoustic trap and tracks drug carriers within organs. MR-based coils (Ø3 mm × 5 mm12) can be used to produce high-contrast spots for precise array positioning and abdomen motion monitoring. The twin trap localizes microbubbles around the tumor tissues for targeted therapy. b Overview of our hardware architecture. The flat 2D phased array consists of 196 (14 × 14) elements. A chamber filled with mixed gases is moved by a XY-table, constituting a time-varying multimedia with the air. A stereo camera module tracks three marks attached to the front wall, offering real-time vision feedback. c–e Examples of PS ball manipulation along the H-, K-, U-shaped trajectories. These pink balls present the positions of the PS ball during its stepwise movement. The larger indicate a 2 mm step in Y direction, and the smaller indicate a 0.5 mm step on in X direction with an optional 0.7 mm step in Y direction for K- trajectory and an optional 1.0 mm step in Y direction for U- trajectory.

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