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Clinical translation of 3D printed pharmaceuticals

Nature Reviews Bioengineering volume 2, pages 801–803 (2024)Cite this article

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The versatility of three-dimensional printed pharmaceuticals, relative to traditionally manufactured ones, could be leveraged for personalized treatment at the point of care, as well as being integrated into mass-manufacturing pipelines. Improvements in quality control and collaboration with regulatory bodies will pave the way to large-scale clinical translation.

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Fig. 1: A workflow comparison of mass manufacturing versus decentralized manufacturing for producing pharmaceuticals.

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Authors and Affiliations

  1. School of Pharmacy, The University of Queensland, Brisbane, Queensland, Australia

    Liam Krueger, Jared A. Miles & Amirali Popat

  2. Department of Clinical, Pharmaceutical and Biological Sciences, University of Hertfordshire, Hatfield, UK

    Atheer Awad

  3. UCL School of Pharmacy, University College London, London, UK

    Abdul W. Basit & Alvaro Goyanes

  4. FABRX, Henwood, Ashford, UK

    Abdul W. Basit & Alvaro Goyanes

  5. FABRX AI, O Saviñao, Spain

    Abdul W. Basit & Alvaro Goyanes

  6. Department of Pharmacology, Pharmacy and Pharmaceutical Technology, I+D Farma, Faculty of Pharmacy, Materials Institute (iMATUS) and Health Research Institute of Santiago de Compostela (IDIS), University of Santiago de Compostela, Santiago de Compostela, Spain

    Alvaro Goyanes

  7. Department of Functional Materials and Catalysis, University of Vienna, Vienna, Austria

    Amirali Popat

Authors
  1. Liam Krueger
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  2. Atheer Awad
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  3. Abdul W. Basit
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  4. Alvaro Goyanes
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  5. Jared A. Miles
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  6. Amirali Popat
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Corresponding authors

Correspondence to Liam Krueger, Atheer Awad, Abdul W. Basit, Alvaro Goyanes, Jared A. Miles or Amirali Popat.

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Competing interests

A.W.B. and A.G. are founders of the pharmaceutical companies FABRX and FABRX AI. A.A. and A.G. are directors of Pharma 3DPI. A.P., L.K. and J.M. declare no competing interests.

Additional information

Related links

Laxxon Medical: https://www.laxxonmedical.com/technology

Pharma3DPI: https://pharma3dpi.org/

Spritam: https://www.accessdata.fda.gov/drugsatfda_docs/nda/2015/207958Orig1s000TOC.cfm#:~:text=Approval%20Date%3A%2007%2F31%2F2015

Triastek: https://www.triastek.com/detail/33.html

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Krueger, L., Awad, A., Basit, A.W. et al. Clinical translation of 3D printed pharmaceuticals. Nat Rev Bioeng 2, 801–803 (2024). https://doi.org/10.1038/s44222-024-00217-x

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