Fig. 1: BA profile changes in both portal and peripheral serum following PHx.

BA profiling post-PHx (a, b) PLS-DA plot showing clear segregation of BA profiles in portal and peripheral serum. Heatmap and hierarchical cluster analysis (c) portal serum (d) peripheral serum. Graphical representation of primary to secondary BA ratio in (e) portal serum (f) peripheral serum. Relative abundance (log normalized) of individual BA showing significant differences in portal serum (g) LCA (h) 6-oxoalbLCA (i) DCA (j) GHDCA (k) TLCA (l) THDCA (m) TbMCA. Data are expressed as mean ± SD (n = 3 each *p < 0.05, **p < 0.001, ***p < 0.0001).