Fig. 2: Hepatic and cell-specific expression of BA receptors, FXR and TGR5 post-PHx. | npj Gut and Liver

Fig. 2: Hepatic and cell-specific expression of BA receptors, FXR and TGR5 post-PHx.

From: Lithocholic acid facilitates release of angiocrine factors by liver sinusoidal endothelial cells during liver regeneration

Fig. 2

Expression of BA receptors in liver tissues after PHx (a) FXR & TGR5 quantified by qRT-PCR. Levels are expressed relative to mean expression in sham rats. The data are normalized to Gapdh mRNA. Results are expressed as mean ± SD. b–d Representative western blot and graphical representation for protein expression of FXR and TGR5. Expression of BA receptors in primary hepatic cells post-PHx. Hepatocytes, LSECs, and HSCs were isolated from rat at day 2 and day 5 post-PHx. e, f FXR (g, h) TGR5. The data are normalized to Gapdh mRNA. Results are expressed as mean ± SD (n = 6 per group), (*p < 0.05, **p < 0.001, ***p < 0.0001).

Back to article page