Fig. 5: TGR5 deficiency alters angiocrine functions of LSECs.

Effect of gene silencing of TGR5 on relative mRNA expression levels of angiocrine genes in vitro (a) Id1 (b) HGF (c) Wnt2. d Representative western blot image of Akt protein expression. e Graphical representation of the quantification of the Akt protein. Data are normalized to Gapdh mRNA. Results are expressed as mean ± SD. (n = 3 each **p < 0.001, ***p < 0.0001).