Fig. 6: Increased secondary BA and angiocrine factors post LDLT in human subjects. | npj Gut and Liver

Fig. 6: Increased secondary BA and angiocrine factors post LDLT in human subjects.

From: Lithocholic acid facilitates release of angiocrine factors by liver sinusoidal endothelial cells during liver regeneration

Fig. 6

BA analysis in human donors of LDLT (a, b). PLSDA and heatmap displaying clear segregation of BA profile at different time-points. Relative abundance (log normalized) for BA showing significant differences at different time-points. c LCA (d) TDCA (e) TUDCA (f) TCA. Concentration of angiocrine factors as determined by ELISA. g Wnt2 (h) HGF in LSEC-CM was checked using ELISA. Data are expressed as mean ± SD (n = 3 each for BA profiling, for ELISA n = 6, **p < 0.001, ***p < 0.0001).

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