Fig. 2: Multi-agent AI system architecture for clinical decision support.

The framework consists of A individual AI agent components with perception, reasoning, and action modules, B autonomous agent-to-agent communication through standardized protocols, C hierarchical human-clinician oversight maintaining final decision authority, and D distributed collaborative problem-solving with specialized agents (MASLD Assessment, PSC Surveillance, Imaging Analysis, and Pathology Integration) working together while maintaining individual task accountability.