Fig. 6: Analysis of the co-enrichment and expression patterns of TCA cycle-related proteins and metabolites in Lactuca sativa under cluster-state PFCA stress.

A show the multi-omics analysis revealed significant differences between the control group and different chain length PFCA-treated groups at the protein and metabolite levels. B show the molecular docking results indicated potential binding sites between PFBA, PFDA, and differentially expressed proteins. C show the analysis of metabolic-protein network remodeling and significantly enriched pathways (including the TCA cycle) revealed the response mechanism to cluster-state PFCA stress.