Collection 

Reproductive aging

Submission status
Closed
Submission deadline

Reproductive aging directly impacts public health, family planning, and quality of life. Understanding the biological mechanisms of reproductive aging can lead to improved fertility treatments and interventions, offering hope to individuals facing age-related infertility. Reproductive aging research can also help mitigate risks associated with late pregnancies, enhance prenatal care, and address age-related reproductive health issues. Moreover, reproductive aging effects extend far beyond age-related fertility declines, as it is intricately associated with systemic health. As individuals age, changes in reproductive hormones can significantly impact various physiological systems. For instance, the decline in estrogen during menopause is associated with increased risks of cardiovascular disease, osteoporosis, and metabolic disorders. Similarly, age-related decreases in testosterone can affect muscle mass, bone density, and mental health in men. Delving into the mechanisms regulating aging in reproductive tissues and their relationship to overall organismal healthspan and longevity is essential for developing comprehensive healthcare strategies that address these broader health issues.

This collection invites research addressing the molecular bases of reproductive longevity, focusing on delaying reproductive decline and curtailing its negative health consequences. Topics of interest include the identification of molecular and cellular mechanisms that regulate aging in reproductive organs and their role in systemic aging.

Woman Reproductive System

Editors

The Collection will publish original research Articles, Reviews, Perspectives and Comments (full details on content types can be found here). Papers will be published in npj aging as soon as they are accepted and then collected together and promoted on the Collection homepage. All Guest Edited Collections are associated with a call for papers and are managed by one or more of our Editorial Board Members and the journal's Editors.

This Collection welcomes submissions from all authors – and not by invitation only – on the condition that the manuscripts fall within the scope of the Collection and of npj aging more generally. See our editorial process page for more details. 

All submissions are subject to the same peer review process and editorial standards as regular npj aging articles, including the journal’s policy on competing interests. The Guest Editors have no competing interests with the submissions, which they handle through the peer-review process. The peer review of any submissions for which the Guest Editors have competing interests is handled by another Editorial Board Member who has no competing interests.  See our Collections guidelines for more details. 

This Collection is not supported by sponsorship.