Articles in 2024

This PrimeView highlights the pathphysiology of Guillain–Barré syndrome, and summarizes the epidemiology, diagnosis and management of this disease. It accompanies the Primer article on this topic by Leonhard et al.

Guillain–Barré syndrome is an acute immune-mediated polyneuropathy that can occur following infections or other rare triggers. In this Primer, Leonhard and colleagues summarize the epidemiology, mechanisms and diagnosis of this disease and discuss its management, patient quality of life and open research questions.

Ectopic pregnancy, defined as the implantation of a developing pregnancy outside of the endometrial cavity of the uterus and the leading cause of early pregnancy maternal mortality.

Ectopic pregnancy is defined as the implantation of a developing pregnancy outside of the endometrial cavity of the uterus and is the leading cause of early-pregnancy maternal mortality. This Primer summarizes the epidemiology, pathophysiology, diagnosis and management of ectopic pregnancy.

This PrimeView highlights the epidemiology, pathophysiology, diagnosis, management and quality of life of individuals with body dysmorphic disorder

Body dysmorphic disorder is a psychiatric condition characterized by constant fixation with perceived flaws in physical appearance. In this Primer, Rück and colleagues discuss the epidemiology and current knowledge of pathogenesis, diagnosis and management of this often-overlooked disorder.

This PrimeView highlights the epidemiology of leprosy, and summarizes the mechanisms, diagnosis and management of this disease. It accompanies the Primer article on this topic by Grijsen et al.

Leprosy is a chronic infectious disease that causes considerable morbidity in marginalized communities. In this Primer, Grijsen et al. summarize the epidemiology and mechanisms of leprosy, discuss its diagnosis, management and patient quality of life, and highlight areas for future research.

Anorectal malformations (ARM), a spectrum of rare congenital anomalies, ranging from a minimally displaced anal canal to a complete fusion of anorectum, vagina and urethra with hypoplastic sphincter and pelvic floor muscle. Almost all ARM subtypes require surgical correction to ensure sufficient anorectal function.

Anorectal malformations (ARM) span a spectrum of rare congenital anomalies of the anus and rectum, ranging from a minimally displaced anal canal to a complete fusion of the anorectum, vagina and urethra with hypoplastic sphincter and pelvic floor muscle. This Primer summarizes the epidemiology, pathophysiology, diagnosis and management of ARM.

This PrimeView highlights the diagnosis of systemic capillary leak syndrome and summarizes the epidemiology, mechanisms and management of this disorder. It accompanies the Primer article on this topic by Druey et al.

Systemic capillary leak syndrome occurs when there is systemically dysregulated fluid homeostasis. This can lead to hypotensive shock, widespread tissue oedema and multi-organ dysfunction syndrome. In this Primer, Druey and colleagues summarize the epidemiology, pathophysiology, diagnosis and management of this condition.

This PrimeView highlights the epidemiology, pathophysiology, diagnosis, management and quality of life of individuals with Rett syndrome.

Rett syndrome is a rare genetic disorder affecting predominantly females resulting in severe physical and mental disability. In this Primer, Gold and colleagues review the epidemiology, mechanisms, diagnosis and treatment as well as highlight the quality of life of individuals with Rett syndrome.

This PrimeView highlights the management of autoimmune haemolytic anaemias, and summarizes the epidemiology, diagnosis and mechanisms of these conditions. It accompanies the Primer article on this topic by Michel et al.

Autoimmune haemolytic anaemias are a group of anaemias mediated by the presence of autoantibodies targeting antigens expressed on red blood cells, leading to their destruction. In this Primer, Michel and colleagues summarize the epidemiology, pathophysiology, diagnosis and management of this condition.

This PrimeView highlights the management of keratoconus and summarizes the epidemiology, mechanisms and diagnosis of this condition. It accompanies the Primer article on this topic by Singh et al.

Keratoconus is a disorder of the eye characterized by progressive thinning and protrusion of the cornea, resulting in vision impairment. In this Primer, Singh et al. review the epidemiology, mechanisms and diagnosis of keratoconus, discuss current management approaches and quality of life, and highlight questions for future research.

This PrimeView highlights the diagnosis of metabolic syndrome and summarizes the epidemiology, mechanisms, management and outlook of this condition. It accompanies the Primer article on this topic by Neeland et al.