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    The global prevalence of hypertension is increasing owing to factors including population ageing and obesity. This series of articles aims to explore basic, clinical and translational aspects of hypertension, including the epidemiology, pathogenesis, patient management and novel therapeutic strategies.

    Image: Vicky Summersby

  • Collection |

    The field of cancer metabolism research is entering its 2nd century since the first description of the changes in metabolism of cancer cells by Otto Warburg and his colleague Seigo Minami in 1923.

    Image: Lara Crow/Springer Nature Limited

  • Focus |

    Population ageing will exacerbate the burden of ageing-related diseases, including chronic kidney disease (CKD).

    Image: L. Crow

  • Collection |

    This Collection aims to highlight the challenges faced by LGBTQ+ colleagues and nephrology patients, and the need to address health inequities.

    Image: Lara Crow

  • Collection |

    The use of artificial intelligence (AI), including machine learning and large language models, is revolutionizing health care, from drug discovery and development, through to applications in the risk stratification, diagnosis, imaging, monitoring, prognostication, and pharmacological and surgical treatment of patients.

    Image: V. Summersby/Springer Nature Limited

  • Focus |

    Regulated cell death contributes to the loss of parenchymal cells in acute and chronic kidney disease and might also modulate immune and inflammatory responses. This Focus issue explores the potential contribution of regulated necrosis pathways — ferroptosis, necroptosis and pyroptosis – to kidney injury.

    Image: L. Crow

  • Collection |

    Selected, recent articles from across the Nature Portfolio that document the recent progress in understanding the biology of EV-mediated cell–cell communication and advances in clinical translation of EVs.

    Image: Vicky Summersby

  • Collection |

    Research into women’s health has suffered from historical neglect and lack of funding.

    Image: Lara Crow/Springer Nature Limited

  • Focus |

    The 17 Sustainable Development Goals (SDGs) underlie a commitment towards ending poverty and hunger, reducing inequalities and tackling climate change, all of which are factors associated with kidney disease.

    Image: L. Crow/Springer Nature Limited

  • Focus |

    Precision medicine aims to tailor medical treatment to specific disease processes with the ultimate aim of optimizing patient outcomes.

    Image: Lara Crow

  • Focus |

    This focus issue highlights some of the innovative dialysis strategies under development that have potential to transform the field with benefits in terms of patient outcomes, access to therapy and environmental sustainability.

    Image: Lara Crow

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