Nature Search

Mapping the genetic landscape across 14 psychiatric disorders

Genomic analyses applied to 14 childhood- and adult-onset psychiatric disorders identifies five underlying genomic factors that explain the majority of the genetic variance of the individual disorders.

Andrew D. Grotzinger
Josefin Werme
Jordan W. Smoller
ResearchOpen Access10 Dec 2025
Nature

Volume: 649, P: 406-415
Depth Habitats of Pelagic Foraminifera during the Pleistocene

BARBARA LIDZ
ALEXIS KEHM
HENDRICK MILLER
Research01 Jan 1968
Nature

Volume: 217, P: 245-247
Presence of a functional vitamin D receptor does not correlate with vitamin D3 phenotypic effects in myeloid differentiation

Alexis Grande
Rossella Manfredini
Sergio Ferrari
Research01 Aug 1997
Cell Death & Differentiation

Volume: 4, P: 497-505
Inexorable land degradation due to agriculture expansion in South American Pampa

The impacts on soil degradation of the massive land-use conversion of South American Pampa grasslands to agriculture are not well documented. This study estimates, over the period 1982–2019, the impacts of such conversion on the sediment cascade and how soil and water resources are affected as a result.

Anthony Foucher
Marcos Tassano
Olivier Evrard
Research13 Feb 2023
Nature Sustainability

Volume: 6, P: 662-670
Validation of human telomere length multi-ancestry meta-analysis association signals identifies POP5 and KBTBD6 as human telomere length regulation genes

Here the authors conduct a multi-ancestry meta-analysis of telomere length, used diverse approaches to identify genes underlying association signals, and experimentally validated POP5 and KBTBD6 as regulators of telomere length in human cells.

Rebecca Keener
Surya B. Chhetri
Alexis Battle
ResearchOpen Access24 May 2024
Nature Communications

Volume: 15, P: 1-21
Identifying gaps in the photographic record of the vascular plant flora of the Americas

Field photographs are essential for research and conservation, but are difficult to access since there is no central database or connection between archives. The 25 leading databases hold only 53% of the plant species of the Americas, illustrating the need for increased work on collecting and standardizing this valuable data.

Nigel C. A. Pitman
Tomomi Suwa
Everton Hilo de Souza
Research29 Jul 2021
Nature Plants

Volume: 7, P: 1010-1014
New insights into the genetic etiology of Alzheimer’s disease and related dementias

Meta-analysis of genome-wide association studies on Alzheimer’s disease and related dementias identifies new loci and enables generation of a new genetic risk score associated with the risk of future Alzheimer’s disease and dementia.

Céline Bellenguez
Fahri Küçükali
Jean-Charles Lambert
ResearchOpen Access04 Apr 2022
Nature Genetics

Volume: 54, P: 412-436
Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

Different functional variants in ADH1B (and elsewhere) in Europeans and Africans strongly affect risk for alcohol dependence. Dependence only partly genetically correlates with consumption, with strong correlations to other psychiatric disorders.

Raymond K. Walters
Renato Polimanti
Arpana Agrawal
Research26 Nov 2018
Nature Neuroscience

Volume: 21, P: 1656-1669
Collision, mantle convection and Tethyan closure in the Eastern Mediterranean

Closure of the Tethys Seaway marked the last connection between the Atlantic and Indo-Pacific oceans. This Review explores how mantle convection and associated volcanic activity caused Tethys Seaway closure and discusses the implications for ocean circulation, faunal diversification and climate.

Eivind O. Straume
Claudio Faccenna
Paolo Ballato
Reviews01 Apr 2025
Nature Reviews Earth & Environment

Volume: 6, P: 299-317
Global Roadkill Data: a dataset on terrestrial vertebrate mortality caused by collision with vehicles

Clara Grilo
Tomé Neves
Eric Guinard
ResearchOpen Access31 Mar 2025
Scientific Data

Volume: 12, P: 1-14
Multi-ancestry genome-wide association meta-analysis of Parkinson’s disease

Multi-ancestry genome-wide association analyses identify new risk loci for Parkinson’s disease, and fine-mapping and co-localization analyses implicate candidate genes whose expression is associated with disease susceptibility.

Jonggeol Jeffrey Kim
Dan Vitale
Ignacio Mata
ResearchOpen Access28 Dec 2023
Nature Genetics

Volume: 56, P: 27-36
TMEM175, SCARB2 and CTSB associations with Parkinson’s disease risk across populations

Wenhua Sun
Claudia Schulte
Masharip Atadzhanov
ResearchOpen Access02 Dec 2025
npj Parkinson's Disease

Volume: 11, P: 1-10
Genome-wide association analyses identify distinct genetic architectures for age-related macular degeneration across ancestries

Multi-ancestry genome-wide analyses identify new risk loci for age-related macular degeneration. Ancestry-specific analyses identify distinct effects at major risk loci, including smaller effect sizes for CFH risk alleles in haplotypes of African ancestry.

Bryan R. Gorman
Georgios Voloudakis
Sudha K. Iyengar
Research02 Dec 2024
Nature Genetics

Volume: 56, P: 2659-2671
Association of genetic scores related to insulin resistance with neurological outcomes in ancestrally diverse cohorts from the Trans-Omics for Precision Medicine (TOPMed) program

Polygenic scores and partitioned polygenic scores related to insulin resistance derived in multiancestry populations show distinct association with neurological outcomes

Chloé Sarnowski
Yixin Zhang
David C. Glahn
ResearchOpen Access24 Sept 2025
Communications Biology

Volume: 8, P: 1-11
Author Correction: Elucidating causative gene variants in hereditary Parkinson’s disease in the Global Parkinson’s Genetics Program (GP2)

Lara M. Lange
Micol Avenali
Masharip Atadzhanov
Amendments and CorrectionsOpen Access13 Sept 2023
npj Parkinson's Disease

Volume: 9, P: 1-3
A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants

Iris Heid, Gonçalo Abecasis, Sudha Iyengar and colleagues report the results of a large genome-wide association meta-analysis of macular degeneration based on over 43,000 subjects. They identify 16 new risk loci, including some very rare coding variants.

Lars G Fritsche
Wilmar Igl
Iris M Heid
Research21 Dec 2015
Nature Genetics

Volume: 48, P: 134-143
Requirement of the coiled-coil domains of p92^c-Fes for nuclear localization in myeloid cells upon induction of differentiation

Enrico Tagliafico
Michela Siena
Sergio Ferrari
Research18 Mar 2003
Oncogene

Volume: 22, P: 1712-1723
Insights into ancestral diversity in Parkinson’s disease risk: a comparative assessment of polygenic risk scores

Paula Saffie-Awad
Spencer M. Grant
Sara Bandres-Ciga
ResearchOpen Access03 Jul 2025
npj Parkinson's Disease

Volume: 11, P: 1-13
Local adaptation to continuous mowing makes the noxious weed Solanum elaeagnifolium a superweed candidate by improving fitness and defense traits

Jesus Chavana
Sukhman Singh
Rupesh R. Kariyat
ResearchOpen Access23 Mar 2021
Scientific Reports

Volume: 11, P: 1-15
Clinical, neuropathological, and genetic characterization of STUB1 variants in cerebellar ataxias: a frequent cause of predominant cognitive impairment

Thomas Roux
Mathieu Barbier
Nicholas Wood
Research27 Jul 2020
Genetics in Medicine

Volume: 22, P: 1851-1862
The LRRK2 p.L1795F variant causes Parkinson’s disease in the European population

Lara M. Lange
Kristin Levine
Masharip Atadzhanov
ResearchOpen Access25 Mar 2025
npj Parkinson's Disease

Volume: 11, P: 1-10
At-admission prediction of mortality and pulmonary embolism in an international cohort of hospitalised patients with COVID-19 using statistical and machine learning methods

Munib Mesinovic
Xin Ci Wong
David Zucman
ResearchOpen Access16 Jul 2024
Scientific Reports

Volume: 14, P: 1-43
Defining suicidality phenotypes for genetic studies: perspectives of the Psychiatric Genomics Consortium Suicide Working Group

Sarah M. C. Colbert
Eric T. Monson
Lea Zillich
ReviewsOpen Access25 Sept 2025
Molecular Psychiatry

Volume: 30, P: 6144-6154
Connectivity and population structure of albacore tuna across southeast Atlantic and southwest Indian Oceans inferred from multidisciplinary methodology

Natacha Nikolic
Iratxe Montes
Sylvain Bonhommeau
ResearchOpen Access24 Sept 2020
Scientific Reports

Volume: 10, P: 1-17
Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium

Jordi Merino
Hassan S. Dashti
Toshiko Tanaka
Research09 Jul 2018
Molecular Psychiatry

Volume: 24, P: 1920-1932
Correction: Clinical, neuropathological, and genetic characterization of STUB1 variants in cerebellar ataxias: a frequent cause of predominant cognitive impairment

Thomas Roux
Mathieu Barbier
Nicholas Wood
Amendments and Corrections22 Dec 2020
Genetics in Medicine

Volume: 23, P: 2021
A transcriptome-wide association study based on 27 tissues identifies 106 genes potentially relevant for disease pathology in age-related macular degeneration

Tobias Strunz
Susette Lauwen
Bernhard H. F. Weber
ResearchOpen Access31 Jan 2020
Scientific Reports

Volume: 10, P: 1-16
Defining the causes of sporadic Parkinson’s disease in the global Parkinson’s genetics program (GP2)

Clodagh Towns
Madeleine Richer
Masharip Atadzhanov
ResearchOpen Access12 Sept 2023
npj Parkinson's Disease

Volume: 9, P: 1-6
Expression of μ-protocadherin is negatively regulated by the activation of the β-catenin signaling pathway in normal and cancer colorectal enterocytes

L Montorsi
S Parenti
A Grande
ResearchOpen Access16 Jun 2016
Cell Death & Disease

Volume: 7, P: e2263
The Scales Project, a cross-national dataset on the interpretation of thermal perception scales

Marcel Schweiker
Amar Abdul-Zahra
Zahra Sadat Zomorodian
ResearchOpen Access26 Nov 2019
Scientific Data

Volume: 6, P: 1-10
Publisher Correction: The Scales Project, a cross-national dataset on the interpretation of thermal perception scales

Marcel Schweiker
Amar Abdul-Zahra
Zahra Sadat Zomorodian
Amendments and CorrectionsOpen Access06 Jan 2020
Scientific Data

Volume: 7, P: 1

Search

Mapping the genetic landscape across 14 psychiatric disorders

Depth Habitats of Pelagic Foraminifera during the Pleistocene

Presence of a functional vitamin D receptor does not correlate with vitamin D3 phenotypic effects in myeloid differentiation

Inexorable land degradation due to agriculture expansion in South American Pampa

Validation of human telomere length multi-ancestry meta-analysis association signals identifies POP5 and KBTBD6 as human telomere length regulation genes

Identifying gaps in the photographic record of the vascular plant flora of the Americas

New insights into the genetic etiology of Alzheimer’s disease and related dementias

Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

Collision, mantle convection and Tethyan closure in the Eastern Mediterranean

Global Roadkill Data: a dataset on terrestrial vertebrate mortality caused by collision with vehicles

Multi-ancestry genome-wide association meta-analysis of Parkinson’s disease

TMEM175, SCARB2 and CTSB associations with Parkinson’s disease risk across populations

Genome-wide association analyses identify distinct genetic architectures for age-related macular degeneration across ancestries

Association of genetic scores related to insulin resistance with neurological outcomes in ancestrally diverse cohorts from the Trans-Omics for Precision Medicine (TOPMed) program

Author Correction: Elucidating causative gene variants in hereditary Parkinson’s disease in the Global Parkinson’s Genetics Program (GP2)

A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants

Requirement of the coiled-coil domains of p92^c-Fes for nuclear localization in myeloid cells upon induction of differentiation

Insights into ancestral diversity in Parkinson’s disease risk: a comparative assessment of polygenic risk scores

Local adaptation to continuous mowing makes the noxious weed Solanum elaeagnifolium a superweed candidate by improving fitness and defense traits

Clinical, neuropathological, and genetic characterization of STUB1 variants in cerebellar ataxias: a frequent cause of predominant cognitive impairment

The LRRK2 p.L1795F variant causes Parkinson’s disease in the European population

At-admission prediction of mortality and pulmonary embolism in an international cohort of hospitalised patients with COVID-19 using statistical and machine learning methods

Defining suicidality phenotypes for genetic studies: perspectives of the Psychiatric Genomics Consortium Suicide Working Group

Connectivity and population structure of albacore tuna across southeast Atlantic and southwest Indian Oceans inferred from multidisciplinary methodology

Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium

Correction: Clinical, neuropathological, and genetic characterization of STUB1 variants in cerebellar ataxias: a frequent cause of predominant cognitive impairment

A transcriptome-wide association study based on 27 tissues identifies 106 genes potentially relevant for disease pathology in age-related macular degeneration

Defining the causes of sporadic Parkinson’s disease in the global Parkinson’s genetics program (GP2)

Expression of μ-protocadherin is negatively regulated by the activation of the β-catenin signaling pathway in normal and cancer colorectal enterocytes

The Scales Project, a cross-national dataset on the interpretation of thermal perception scales

Publisher Correction: The Scales Project, a cross-national dataset on the interpretation of thermal perception scales

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