Nature Search

Near future projections of tropical cyclone tracks over the Bay of Bengal using high resolution CMIP6 models

Rushikesh Adsul
Vineet Kumar Singh
C. Gnanaseelan
ResearchOpen Access16 Jan 2026
Scientific Reports

P: 1-13
Cysteinyl leukotriene type I receptor desensitization sustains Ca²⁺-dependent gene expression

Rather than turning off the biological response, desensitization of the cysteinyl leukotriene type I receptor sustains long-term signalling in the immune system.

Siaw-Wei Ng
Daniel Bakowski
Anant B. Parekh
Research09 Jan 2012
Nature

Volume: 482, P: 111-115
Depletion of InsP₃ stores activates a Ca²⁺ and K⁺ current by means of a phosphatase and a diffusible messenger

Anant B. Parekh
Heinrich Terlau
Walter Stühmer
Research26 Aug 1993
Nature

Volume: 364, P: 814-818
Store-operated CRAC channels: function in health and disease

Ca²⁺ release-activated Ca²⁺(CRAC) channels are involved in a vast array of cellular responses, and abnormal channel activity has now been linked to many diseases including immunodeficiency and autoimmunity disorders, allergy, and cancer. Here, Parekh discusses recent advances in understanding the molecular basis, gating and function of CRAC channels, as well as the therapeutic potential of CRAC channel inhibitors.

Anant B. Parekh
Reviews16 Apr 2010
Nature Reviews Drug Discovery

Volume: 9, P: 399-410
Sequential forward and reverse transport of the Na⁺ Ca²⁺ exchanger generates Ca²⁺ oscillations within mitochondria

Mitochondrial Ca²⁺ homoeostasis is tightly regulated and export of Ca²⁺ is mediated by an Na⁺Ca²⁺ exchanger. Here authors show that in depolarised mitochondria the exchanger initially operates in reverse mode, transporting cytosolic Ca²⁺ into the matrix before it reverts to its forward mode state.

Krishna Samanta
Gary R. Mirams
Anant B. Parekh
ResearchOpen Access11 Jan 2018
Nature Communications

Volume: 9, P: 1-10
Selective recruitment of different Ca²⁺-dependent transcription factors by STIM1-Orai1 channel clusters

Endoplasmic reticulum Ca2+ sensing STIM proteins and plasma membrane Orai1 channels together regulate Ca2+ influx in eukaryotic cells. Here authors show that two Ca2+-dependent transcription factors, NFAT1 and c-fos, have different requirements for the number of STIM1-Orai1 clusters and on the Ca2+ flux through the clusters.

Yu-Ping Lin
Daniel Bakowski
Anant B. Parekh
ResearchOpen Access07 Jun 2019
Nature Communications

Volume: 10, P: 1-14
Cracking the calcium entry code

A sharp increase in the concentration of calcium ions in a cell is a key biological signal. Now a vital component of a major route by which calcium ions flow into cells has been identified.

Anant B. Parekh
News & Views10 May 2006
Nature

Volume: 441, P: 163-165
A CRAC current tango

Rises in cytoplasmic Ca²⁺ concentration control a diverse array of key cellular functions. One ubiquitous route for raising Ca²⁺ concentration is through store-operated calcium channels in the plasma membrane. However, the molecular basis of store-operated entry has remained a mystery. Now, exciting new research may have identified the molecular composition of a store-operated channel.

Anant B Parekh
News & Views01 Jul 2006
Nature Cell Biology

Volume: 8, P: 655-656
Room temperature, metal-free, CDI-promoted, ex-situ protocol for S-methyl thioester synthesis

Manisha A. Patel
Vandana Sharma
Anant R. Kapdi
ResearchOpen Access27 May 2025
Scientific Reports

Volume: 15, P: 1-13
Dynamical and moist thermodynamical processes associated with Western Ghats rainfall decadal variability

Subrota Halder
Anant Parekh
C. Gnanaseelan
ResearchOpen Access08 Feb 2022
npj Climate and Atmospheric Science

Volume: 5, P: 1-11
Temporal and spatial aggregation of rainfall extremes over India under anthropogenic warming

Gopinadh Konda
Jasti S. Chowdary
Anant Parekh
ResearchOpen Access31 May 2024
Scientific Reports

Volume: 14, P: 1-11
Improvement in the skill of CMIP6 decadal hindcasts for extreme rainfall events over the Indian summer monsoon region

Gopinadh Konda
Jasti S. Chowdary
Anant Parekh
ResearchOpen Access08 Dec 2023
Scientific Reports

Volume: 13, P: 1-13

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