Nucleotide excision repair is a conserved DNA repair system. Here, the authors explore the structural details of damage identification by UvrA and reveal the UvrA-UvrB-DNA complex architecture at varying stoichiometries. They propose a model for damage recognition by UvrA and lesion hand-off to UvrB.
- Marianna Genta
- Giulia Ferrara
- Riccardo Miggiano
