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Current applications of NV centers in diamond as spin-photon interfaces for quantum networks are limited by low coherent photon emission. Here, the authors integrate a coherently controlled NV spin qubit with an open microcavity to achieve Purcell-enhanced emission and demonstrate spin-photon state generation.

Controlling supercurrent pathways in a Josephson junction can lead to new functionalities. Here, Lahabi et al. demonstrate the tailoring of two distinct supercurrent channels in a ferromagnetic disk containing a magnetic vortex.

All quantum systems are connected to their environment, and this reduces their quantumness through decoherence. Here, the authors show that the interaction between a macroscale quantum system—a micromechanical oscillator—and its environment leads to non-Markovian Brownian motion

Constitutional mismatch repair deficiency (CMMRD) is associated with high cancer incidence early in life. Here, the authors perform a genomic analysis of CMMRD-associated tumors and find mutational patterns influenced by the affected mismatch repair gene, tumour type, and treatment history.

Radical methylation ranks among the most important yet challenging transformations in chemistry and biology, which often involves small and unstable radical intermediates, and results in low reactivity and poor selectivity. Herein, the authors report a bioinspired transfer methylation protocol for the direct and selective C(sp²)-H methylation of heteroarenes.

AmpG is an MFS importer of bacterial cell wall fragments. Here, authors present a cryoEM structure and supporting mutagenesis to illuminate AmpG’s essential role in bacterial fitness and derepression of broad-spectrum β-lactam antibiotic resistance.

Materials with topologically nontrivial band structures possess exotic electronic transport properties however they are naturally constrained below three dimensions. Here, the authors demonstrate how analogous systems with n−1 dimensions may be constructed from Josephson junctions of n-terminals.

Probing the evolution of mixed-phase states in materials offers unique insights into the microscopic mechanism of phase transitions. Here, Mattoni et al. report imaging of nanoscale formation and growth of insulating domains across the metal-insulator transition in NdNiO₃thin films, uncovering a rich interplay between structural and electronic degrees of freedom.

Quantum transport in superconductors remains difficult to study due to the typically small Fermi wavelength. Here, Thierschmann et al. demonstrate a superconducting quantum point contact with split gate technology at the superconducting LaAlO₃/SrTiO₃ interface and, due to its two-dimensionality, identify three regimes of quantum transport.

Single-molecule junctions provide a unique platform to understand how molecular structure affects electronic transport. Now it has been shown that electronic transport through a π-stacked dimer can be precisely controlled when pulling it apart. This behaviour is caused by quantum interference effects that are turned ON or OFF depending on dimer conformation.

Distinguishing band and Mott insulators experimentally represents a longstanding challenge. Here, the authors demonstrate a momentum-resolved signature of a dimerized Mott-insulator in the out-of-plane spectral function of Nb₃Br₈.

Here, the authors study the population-level impact of antimicrobial resistance genes (ARGs). By analyzing 8972 metagenomes and 3,096 gut microbiomes from healthy individuals not taking antibiotics, they demonstrate significant correlations between both the total ARG abundance and diversity and per capita antibiotic usage rates across ten countries spanning three continents. Using a collection of 154,723 human-associated metagenome assembled genomes (MAGs) they link these ARGs to microbial taxa and horizontal gene transfer.

Multi-terminal superconducting Josephson junctions are used to induce topologically protected transitions between gapless and gapped states, showing the potential for creating artificial topological materials.

Observation of the entire dispersion relation for spin waves remains a challenge which prevents the full understanding of many intriguing magnetic properties. Here, the authors develop a table-top all-optical approach to map out the dispersion curve of pure-magnetostatic waves in magnetic films.

Electron spins in diamond allow magnetometry with high sensitivity, but the bandwidth in the microwave regime is limited to a narrow band around their resonance frequency. Here, the authors solve this problem by coupling the spins to a thin film of yttrium iron garnet, exploiting the non-linear spin-wave dynamics of the magnet.

Hydrogen atom abstraction from C(sp³)–H bonds of naturally abundant alkanes for alkyl radical generation represents a promising yet underexplored strategy in the alkylation reaction designs. Here the authors show a photo-induced and chemical oxidant-free cross-dehydrogenative coupling between alkanes and heteroarenes using catalytic chloride and cobalt catalyst.

The direct deoxygenative coupling of aldehydes or ketones to construct C(sp³)−C(sp³) bond remains a scientific challenge. Here the authors use a nickel−catalyzed reductive homo-coupling of moisture- and air-stable hydrazones generated in-situ from naturally abundant aldehydes and ketones to construct challenging C(sp³)−C(sp³) bonds.

The cleavage and formation of carbon−carbon bonds is an important strategy for structural modifications in organic syntheses. Herein, the authors present a photoinduced method to construct biaryl compounds through dual inert C−C bond cleavage.

Nonlinear dissipation is frequently observed in nanomechanical resonators, but its microscopic origin remains unclear. Here, nonlinear damping is found to be enhanced in graphene nanodrums close to internal resonance conditions, providing insights on the mechanisms at the basis of this phenomenon.

Atomically thin porous graphene is promising for filtration and sieving applications. Here the authors, using a laser-actuated micro-drum device of bilayer graphene with controlled number of nanopores, and measuring the permeation rate of different gases, show that it can also be used for permeation-based sensing.

Electronics and magnetic phase transitions typically do not involve mechanical degrees of freedom directly, but their impact on thermodynamic properties affects the mechanical response of a material. Here the authors show that resonators made from 2D materials exhibit anomalies at phase transitions.

Heck coupling of alkenes with organic halides, arenes or organometallics poses sustainability issues due to hazardous waste formation and use of oxidants. Here, the authors show an oxidant-free alkyl Heck-coupling of vinylarenes with umpolung aldehydes, liberating H₂, N₂ and H₂O as sole side products.

Synthesis of biaryls by coupling strategies is unavoidably accompanied by stoichiometric metal waste. Here, the authors report the homo- and cross-electrophile coupling by using hydrazine as metal surrogate, only liberating N₂ and H₂ as side products.

Alcohols are more naturally abundant than carbonyl compounds, which in turn are well known for their reactivity in Grignard reactions. Here, the authors showcase a distinct Grignard-like reactivity by using alcohols as coupling partners with hydrazones and synthesize more complex alcohols under ruthenium catalysis.

Quantum dot spin qubits in Si can be controlled using micromagnet-based electric-dipole spin resonance, but experiments have been limited to small 1D arrays. Here the authors address qubit control in 2D Si arrays, demonstrating low-frequency control of qubits in a 2 x 2 array using hopping gates.

A material weakly linking two superconductors may itself exhibit superconductivity whilst its material properties strongly influence the nature of the supercurrent. Here, the authors identify a supercurrent with p-wave symmetry in such a Josephson junction made of topologically non-trivial material.

The mechanical resonances of atomically thin membranes show nonlinear responses at driving forces in the picoNewton range. Here, the authors develop a contactless method to extract the Young’s modulus of 2D materials from the nonlinear dynamic response of these nanomechanical resonators.

Quantum dots in a nanowire are one possible approach to creating a solid-state quantum simulator. Here, the authors demonstrate the coupling of electronic states in a double quantum dot to form Andreev molecule states; a potential building block for longer chains suitable for quantum simulation.

In information theory one is interested in how much information can be reliably sent over noisy communication channels. Here the authors show that for channels with memory the optimal rate of information transmission is uncomputable.

Quantum interference plays an important role in single-molecule charge transport with sharp features predicted in transmission. Here, the authors reconstruct the destructive quantum interference feature of a mechanosensitive molecule at ambient, revealing the smearing effect of thermal fluctuations.

A Josephson junction with a weak link made of the quantum spin Hall insulator HgTe shows evidence of topological superconductivity in response to an a.c. excitation.

Magnetic phase transitions typically lead to changes in a materials magnetostrictive properties. Here, Šiškins et al use the motion of a nanodrum to study the nonlinear magneto-mechanical response of FePS₃, and observe changes in the nonlinear stiffness and damping near the Neel temperature.

The kinesin-3 motor KIF1A is inefficient in its single-headed form but recent studies have predicted that force transmission is enabled when motors work in teams. Here Oriola et al.show that singleheaded KIF1A motors can pull tubes from lipid vesicles, and form left-handed helices around microtubules by generating lateral forces.

Experimentally validated kinetic simulations uncover transient enhancement of GPCR ternary complex formation by allokairic effectors.

A long-standing debate on the foundation of quantum mechanics is whether wave–particle duality and the uncertainty principle are equivalent. Here Coles et al. show that the wave–particle duality relation corresponds to a formulation of the uncertainty principle in terms of min- and max-entropies.

Long-range magnetic order hardly ever emerges in a two-dimensional system due to the competition of fundamental magnetic interactions. Here, Girovskyet al. directly observe a long-range ferrimagnetic order emerging in a two-dimensional supramolecular Kondo lattice.

MukBEF, the bacterial structural maintenance of chromosomes complex, is known to associate with origins of replication and topoisomerase IV. Here the authors show an association of MukBEF with MatP and replication termination regions, important for proper sister chromatid decatenation and segregation.

Oblivious transfer is a standard primitive for cryptography between two parties which do not trust each other. Here, the authors propose a continuous-variable protocol which is secure against a dishonest party with bounded quantum storage capacity, and realize a proof-of-principle implementation.

The authors develop a nanomechanical straining technique to reveal previously inaccessible intervalley excitons in suspended WSe₂ and WS₂. They further unveil a mechanism that brightens the dark intervalley excitons through strain-controlled hybridization with intravalley excitons.

The direct co-conversion of CH₄ and CO₂ into valuable chemicals has been a longstanding scientific pursuit. Here, the authors present a photo-driven process that reforms these greenhouse gases together to generate CH₃OH and CO over AuPd/GaN.

Extensive research efforts have been directed towards the development of PET hydrolases with improved activity, but template enzymes used are limited. Here, the authors report a PET hydrolase from Cryptosporangium aurantiacum (CaPETase) that exhibits high thermostability and PET degradation activity at ambient temperatures and determine its crystal structure.

The structural cross-talk between components of the eukaryotic cytoskeleton remains poorly understood. Here the authors engineer an actin-binding microtubule tip-tracking protein that guides microtubule growth along actin bundles, and allows microtubule growing ends to pull and bundle actin filaments.

Exploring new mechanics regime, researchers created centimeter-long, nanometer-thin resonators, achieving unmatched room temperature mechanical isolation via cutting edge nanoengineering and machine learning design; rivaling cryogenic counterparts.