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Showing 1–6 of 6 results

Advanced filters: Author: Chenshuai Li Clear advanced filters

TBC1D1 functions as a negative regulator of satellite cells for muscle regeneration

MuSCs are vital for muscle renewal with unclear regulatory mechanisms. Here, the authors show that cytosolic TBC1D1 inhibits nuclear entry of the AS160-STAT3 complex and regulates MuSC proliferation. Deficiency of TBC1D1 improves muscle regeneration.

Xinyu Yang
Ye Cao
Hong-Yu Wang
ResearchOpen Access18 Nov 2025
Nature Communications

Volume: 16, P: 1-17
Nuclear entry of AS160 as a transcriptional regulator of satellite cells for muscle regeneration

The mechanisms resulting in muscle satellite cell dysfunction in diabetes are not well understood. Here, the authors show that AS160 functions in the nucleus to regulate satellite cell proliferation and that its impaired nuclear entry is linked to diabetic myopathy.

Xinyu Yang
Ye Cao
Shuai Chen
ResearchOpen Access15 Oct 2025
Nature Communications

Volume: 16, P: 1-19
AS160 is a lipid-responsive regulator of cardiac Ca²⁺ homeostasis by controlling lysophosphatidylinositol metabolism and signaling

How obesity causes cardiac dysfunction is not fully understood. Here, the authors show that a high fat diet inhibits the activity of RabGAP AS160 in the heart, causing pathological metabolic remodeling and altering calcium signaling.

Shu Su
Chao Quan
Shuai Chen
ResearchOpen Access06 Nov 2024
Nature Communications

Volume: 15, P: 1-18
CD36 facilitates fatty acid uptake by dynamic palmitoylation-regulated endocytosis

The mechanistic details of fatty acid uptake into cells remains poorly understood. Here, the authors identify CD36 internalization via cavaeolae and demonstrate dynamic palmitoylationof CD36 is required for endocytic uptake of fatty acids.

Jian-Wei Hao
Juan Wang
Tong-Jin Zhao
ResearchOpen Access21 Sept 2020
Nature Communications

Volume: 11, P: 1-16
Investigating mitophagy mechanisms in bronchopulmonary dysplasia through bioinformatics

Chenshuai Li
Yalei Wang
Yali Li
Research09 Aug 2025
Pediatric Research

P: 1-10
A Magnetically Recoverable Fe₃O₄–NH₂–Pd Sorbent for Capture of Mercury from Coal Derived Fuel Gas

Lina Han
Qinglian Li
Jiancheng Wang
ResearchOpen Access07 Aug 2017
Scientific Reports

Volume: 7, P: 1-10