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Showing 1–7 of 7 results
Advanced filters: Author: Christof Geldmacher Clear advanced filters

  • Bauer et al. analyze blood-based immune and transcriptomic markers in tuberculosis patients to identify treatment failure and recurrence. They find that specific markers reliably detect microbiological non-conversion during treatment and recurrence after therapy, providing a sputum-independent tool for patient monitoring.

    • Bernadette Bauer
    • Mohamed I. M. Ahmed
    • Knut Lönnroth
    ResearchOpen Access
    Communications Medicine
    Volume: 6, P: 1-13

  • Authors carry out an immunogenetic and virologic analysis of nasopharyngeal and peripheral blood samples, finding that early nucleocapsid-specific T cell responses associate with control of SARS-CoV-2 in the upper airways and reduced systemic inflammation before seroconversion.

    • Tabea M. Eser
    • Olga Baranov
    • Christof Geldmacher
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-13

  • Familial adenomatous polyposis (FAP) is an inherited gastrointestinal syndrome associated with duodenal adenoma formation. Here the authors show that IL17A-producing NKp44- group 3 innate lymphoid cells accumulate in FAP duodenal tissue and are associated with duodenal adenoma formation in patients with FAP.

    • Kim M. Kaiser
    • Jan Raabe
    • Jacob Nattermann
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-19

  • Infection with SARS-COV-2 can result in self-limited upper airway infection or progress to a more systemic inflammatory condition including pneumonic COVID-19. Here the authors utilise a multi-omics approach to interrogate the immune response of patients with self-limiting upper respiratory SARS-CoV-2 infection and reveal a temporal immune trajectory they associate with viral containment and restriction from pneumonic progressive disease.

    • Kami Pekayvaz
    • Alexander Leunig
    • Leo Nicolai
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-21