A map of nucleosome positions across the Drosophila genome reveals a chromatin organization that can be compared with that of budding yeast. The Drosophila nucleosome distribution pattern indicates that RNA polymerase II can access the transcription start site of active genes unimpeded by nucleosomes, but there is a nucleosome positioned at the site where the polymerase pauses.
- Travis N. Mavrich
- Cizhong Jiang
- B. Franklin Pugh