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Showing 51–100 of 337 results

Advanced filters: Author: D. Sheehan Clear advanced filters

Genome editing in butterflies reveals that spalt promotes and Distal-less represses eyespot colour patterns

Transcription factors Distal-less(Dll) and spalt were co-opted during the evolution of butterfly eyespots. Here, Zhang and Reed use CRISPR/Cas9 genome editing to show that while spalt is a positive regulator of eyespots as predicted, Dll knockouts have positive effects on both eyespot size and number, thus suggesting that Dllis an eyespot repressor, not an activator as previously thought.

Linlin Zhang
Robert D. Reed
ResearchOpen Access15 Jun 2016
Nature Communications

Volume: 7, P: 1-7
Home-based transcranial direct current stimulation treatment for major depressive disorder: a fully remote phase 2 randomized sham-controlled trial

A randomized, sham-controlled, superiority trial of a 10-week course of home-based transcranial direct current stimulation found greater improvements in depressive symptoms with active compared to sham stimulation in major depressive disorder.

Rachel D. Woodham
Sudhakar Selvaraj
Cynthia H. Y. Fu
ResearchOpen Access21 Oct 2024
Nature Medicine

Volume: 31, P: 87-95
Somatic linker histones cause loss of mesodermal competence in Xenopus

Oliver C. Steinbach
Alan P. Wolffe
Ralph A.W. Rupp
Research25 Sept 1997
Nature

Volume: 389, P: 395-399
Alterations in intestinal bile acid transport provide a therapeutic target in patients with post-bariatric hypoglycaemia

FGF19 increase in post-bariatric hypoglycaemia is mediated by bile acid dysregulation, and can be countered by inhibiting bile acid transport.

Snehal N. Chaudhari
Yingjia Chen
Mary-Elizabeth Patti
Research04 Apr 2025
Nature Metabolism

Volume: 7, P: 792-807
N-Acetyl-L-Tyrosine as a Tyrosine Source during Total Parenteral Nutrition in Adult Rats

A Im Haesook
D Meyer Paul
Lewis D Stegink
Research01 Jun 1985
Pediatric Research

Volume: 19, P: 514-518
Distortions of visuotopic map match orientation singularities in primary visual cortex

Aniruddha Das
Charles D. Gilbert
Research05 Jun 1997
Nature

Volume: 387, P: 594-598
Fingerprint of ozone depletion in the spatial and temporal pattern of recent lower-stratospheric cooling

V. Ramaswamy
M. D. Schwarzkopf
W. J. Randel
Research15 Aug 1996
Nature

Volume: 382, P: 616-618
A biosensor that uses ion-channel switches

B. A. Cornell
V. L. B. Braach-Maksvytis
R. J. Pace
Research05 Jun 1997
Nature

Volume: 387, P: 580-583
Resting-state functional connectivity, cortical GABA, and neuroactive steroids in peripartum and peripartum depressed women: a functional magnetic resonance imaging and spectroscopy study

Kristina M. Deligiannidis
Christina L. Fales
Constance M. Moore
Research17 Oct 2018
Neuropsychopharmacology

Volume: 44, P: 546-554
Neogene mass extinction of Western Atlantic molluscs

Steven M. Stanley
Lyle D. Campbell
Research08 Oct 1981
Nature

Volume: 293, P: 457-459
Coevolution of religious and political authority in Austronesian societies

Phylogenetic methods applied to ethnographic data show that systems of religious and political authority have worked synergistically over millennia of Austronesian cultural evolution, without showing a clear tendency to become more or less distinct.

Oliver Sheehan
Joseph Watts
Quentin D. Atkinson
ResearchOpen Access10 Nov 2022
Nature Human Behaviour

Volume: 7, P: 38-45
Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

The goals, resources and design of the NHLBI Trans-Omics for Precision Medicine (TOPMed) programme are described, and analyses of rare variants detected in the first 53,831 samples provide insights into mutational processes and recent human evolutionary history.

Daniel Taliun
Daniel N. Harris
Gonçalo R. Abecasis
ResearchOpen Access10 Feb 2021
Nature

Volume: 590, P: 290-299
Assessing simulation-based supervised machine learning for demographic parameter inference from genomic data

Arnaud Quelin
Frédéric Austerlitz
Flora Jay
ResearchOpen Access06 Jun 2025
Heredity

Volume: 134, P: 417-426
Aberrant activation of TCL1A promotes stem cell expansion in clonal haematopoiesis

Using data from a single time point, passenger-approximated clonal expansion rate (PACER) estimates the fitness of common driver mutations that lead to clonal haematopoiesis and identifies TCL1A activation as a mediator of clonal expansion.

Joshua S. Weinstock
Jayakrishnan Gopakumar
Siddhartha Jaiswal
Research12 Apr 2023
Nature

Volume: 616, P: 755-763
Decay characteristics of HIV-1-infected compartments during combination therapy

Alan S. Perelson
Paulina Essunger
David D. Ho
Research08 May 1997
Nature

Volume: 387, P: 188-191
Author Correction: Stereotactic radiosurgery for patients with brain metastases: current principles, expanding indications and opportunities for multidisciplinary care

Alireza Mansouri
Ahmad Ozair
Manmeet S. Ahluwalia
Amendments and Corrections03 Oct 2025
Nature Reviews Clinical Oncology

Volume: 22, P: 996
A human-specific enhancer fine-tunes radial glia potency and corticogenesis

HARE5, a human accelerated region enhancer, modulates cortical development by influencing neural progenitor cell behaviour, leading to an enlarged neocortex with increased functional independence between cortical regions through amplified WNT signalling.

Jing Liu
Federica Mosti
Debra L. Silver
Research14 May 2025
Nature

Volume: 643, P: 1321-1332
Thalamic modulation of high-frequency oscillating potentials in auditory cortex

Daniel S. Barth
Kurt D. MacDonald
Research05 Sept 1996
Nature

Volume: 383, P: 78-81
Estimation of self-motion by optic flow processing in single visual interneurons

Holger G. Krapp
Roland Hengstenberg
Research05 Dec 1996
Nature

Volume: 384, P: 463-466
Transition-state stabilization as a measure of the efficiency of antibody catalysis

Jon D. Stewart
Stephen J. Benkovic
Research01 Jun 1995
Nature

Volume: 375, P: 388-391
Upper-crustal strength inferred from stress measurements to 6 km depth in the KTB borehole

Mark D. Zoback
R. Apel
L. Vernik
Research01 Oct 1993
Nature

Volume: 365, P: 633-635
Rational engineering of activity and specificity in a serine protease

Quoc D. Dang
Enriqueta R. Guinto
Enrico Di Cera
Research01 Feb 1997
Nature Biotechnology

Volume: 15, P: 146-149
Spontaneous assembly of a hinged coordination network

Geoffrey B. Gardner
D. Venkataraman
Stephen Lee
Research27 Apr 1995
Nature

Volume: 374, P: 792-795
Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation

R. Baskaran
L. D. Wood
J. Y. J. Wang
Research29 May 1997
Nature

Volume: 387, P: 516-519
Potential accumulation of a CFC-replacement degradation product in seasonal wetlands

T. K. Tromp
M. K. W. Ko
N. D. Sze
Research27 Jul 1995
Nature

Volume: 376, P: 327-330
An interleukin 1 like factor stimulates bone resorption in vitro

Maxine Gowen
David D. Wood
R. Graham G. Russell
Research24 Nov 1983
Nature

Volume: 306, P: 378-380
Stress-induced domain reorientation in urea inclusion compounds

Michael E. Brown
Mark D. Hollingsworth
Research27 Jul 1995
Nature

Volume: 376, P: 323-327
MCM3 complex required for cell cycle regulation of DNA replication in vertebrate cells

M. A. Madine
C.-Y. Khoo
R. A. Laskey
Research01 Jun 1995
Nature

Volume: 375, P: 421-424
Deglacial sea-level record from Tahiti corals and the timing of global meltwater discharge

Edouard Bard
Bruno Hamelin
Francis Rougerie
Research18 Jul 1996
Nature

Volume: 382, P: 241-244
Entropic control of particle motion using passive surface microstructures

A. D. Dinsmore
A. G. Yodh
D. J. Pine
Research19 Sept 1996
Nature

Volume: 383, P: 239-242
Slow rotation of the Sun's interior

Y. Elsworth
R. Howe
D. O. Gough
Research24 Aug 1995
Nature

Volume: 376, P: 669-672
Vertical mantle flow associated with a lithospheric drip beneath the Great Basin

Seismic anisotropy data for the Great Basin region of the western United States, coupled with tomographic images, help delineate a northeast-dipping lithospheric drip. Numerical experiments suggest that the drip could have formed owing to gravitational instability triggered by a density increase of about 1% and a temperature increase of about 10%.

John D. West
Matthew J. Fouch
Linda T. Elkins-Tanton
Research24 May 2009
Nature Geoscience

Volume: 2, P: 439-444
Neoantigen-specific cytotoxic Tr1 CD4 T cells suppress cancer immunotherapy

Type 1 regulatory T cells (Tr1) represent a major obstacle that compromises naturally occurring and therapeutically induced tumour-specific immunity.

Hussein Sultan
Yoshiko Takeuchi
Robert D. Schreiber
ResearchOpen Access24 Jul 2024
Nature

Volume: 632, P: 182-191
Homeotic genes and the regulation and evolution of insect wing number

Sean B. Carroll
Scott D. Weatherbee
James A. Langeland
Research04 May 1995
Nature

Volume: 375, P: 58-61
Dimeric association and segmental variability in the structure of human CD4

Hao Wu
Peter D. Kwong
Wayne A. Hendrickson
Research29 May 1997
Nature

Volume: 387, P: 527-530
High concentrations and photochemical fate of oxygenated hydrocarbons in the global troposphere

Hanwant B. Singh
M. Kanakidou
D. J. Jacob
Research02 Nov 1995
Nature

Volume: 378, P: 50-54
Increased activity of northern vegetation inferred from atmospheric CO₂ measurements

C. D. Keeling
J. F. S. Chin
T. P. Whorf
Research11 Jul 1996
Nature

Volume: 382, P: 146-149
Two-way exchange between the Easter mantle plume and the Easter microplate spreading axis

K. M. Haase
C. W. Devey
S. L. Goldstein
Research25 Jul 1996
Nature

Volume: 382, P: 344-346
Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

David Hockenbery
Gabriel Nuñez
Stanley J. Korsmeyer
Research22 Nov 1990
Nature

Volume: 348, P: 334-336
Assembly of porphyrin building blocks into network structures with large channels

B. F. Abrahams
B. F. Hoskins
R. Robson
Research30 Jun 1994
Nature

Volume: 369, P: 727-729
Detection of postseismic fault-zone collapse following the Landers earthquake

Didier Massonnet
Wayne Thatcher
Hélèna Vadon
Research15 Aug 1996
Nature

Volume: 382, P: 612-616
A neuronal learning rule for sub-millisecond temporal coding

Wulfram Gerstner
Richard Kempter
Hermann Wagner
Research05 Sept 1996
Nature

Volume: 383, P: 76-78
Genetic mapping of a susceptibility locus for insulin-dependent diabetes mellitus on chromosome llq

L. Hashimoto
C. Habita
C. Julier
Research08 Sept 1994
Nature

Volume: 371, P: 161-164
The carbon-isotope shift at the Permian/Triassic boundary in the southern Alps is gradual

Mordeckai Magaritz
Richard Bart
William T. Holser
Research28 Jan 1988
Nature

Volume: 331, P: 337-339
Improving enzyme–electrode contacts by redox modification of cofactors

Azalla Riklin
Eugenii Katz
Andreas F. Bückmann
Research24 Aug 1995
Nature

Volume: 376, P: 672-675
Critical protective role of mast cells in a model of acute septic peritonitis

Bernd Echtenacher
Daniela N. Männel
Lothar Hültner
Research02 May 1996
Nature

Volume: 381, P: 75-77
Insect parasitoid species respond to forest structure at different spatial scales

Jens Roland
Philip D. Taylor
Research17 Apr 1997
Nature

Volume: 386, P: 710-713
An organic solid with wide channels based on hydrogen bonding between macrocycles

D. Venkataraman
Stephen Lee
Jeffrey S. Moore
Research13 Oct 1994
Nature

Volume: 371, P: 591-593
Prolactin — a pleiotropic factor in health and disease

Prolactin is mainly known for its involvement in the regulation of lactation. In this Review, the authors describe other newly discovered roles of prolactin in human health and disease and discuss new data on the pathological states of hypoprolactinaemia and hyperprolactinaemia.

Valérie Bernard
Jacques Young
Nadine Binart
Reviews21 Mar 2019
Nature Reviews Endocrinology

Volume: 15, P: 356-365
A Longitudinal Cohort Study of Transepidermal Water Loss in the First Six Months of Life as a Predictor of Subsequent Atopic Dermatitis

C McCarthy
A Gallagher
J O'B Hourihane
Research01 Nov 2011
Pediatric Research

Volume: 70, P: 293

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