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Showing 1–12 of 12 results

Advanced filters: Author: Da-Eun Kim Clear advanced filters

Publisher Correction: Fusion guide RNAs for orthogonal gene manipulation with Cas9 and Cpf1

Jiyeon Kweon
An-Hee Jang
Yongsub Kim
Amendments and CorrectionsOpen Access16 Jan 2018
Nature Communications

Volume: 9, P: 1
Fusion guide RNAs for orthogonal gene manipulation with Cas9 and Cpf1

Cas9 and Cpf1 have both been adapted for genome engineering, editing and gene expression regulation. Here the authors design a fusion guide RNA that can interact with both proteins for multiple and orthogonal genome manipulation.

Jiyeon Kweon
An-Hee Jang
Yongsub Kim
ResearchOpen Access23 Nov 2017
Nature Communications

Volume: 8, P: 1-6
Genome-wide target specificity of CRISPR RNA-guided adenine base editors

Unbiased detection of off-target editing by adenine base editors in vitro uncovers differences in the specificity patterns of adenine and cytosine base editors, and of unmodified Cas9.

Daesik Kim
Da-eun Kim
Jin-Soo Kim
Research04 Mar 2019
Nature Biotechnology

Volume: 37, P: 430-435
A novel TREM2 L15Q in signal peptide domain and its influence on Aβ pathogenicity

Danyeong Kim
Heewon Bae
Seong Soo A. An
ResearchOpen Access23 Jan 2026
npj Dementia

Volume: 2, P: 1-9
The lateralized LC-NAergic system distinguishes vicarious versus direct fear in mice

Fear arises directly or vicariously, with the LC-NA system involved in both. Here, the authors show that the right LC → ACC pathway is key for vicarious fear, while BNST and CeA provide distinct inputs to LC, highlighting its complex role in fear.

Jong-Hyun Kim
Da-Eun Choi
Hee-Sup Shin
ResearchOpen Access10 Mar 2025
Nature Communications

Volume: 16, P: 1-12
Adenine base editing in mouse embryos and an adult mouse model of Duchenne muscular dystrophy

Adenine base editing is used to treat a mouse model of Duchenne muscular dystrophy and to create defined mutations in mouse embryos.

Seuk-Min Ryu
Taeyoung Koo
Jin-Soo Kim
Research27 Apr 2018
Nature Biotechnology

Volume: 36, P: 536-539
Genome-wide specificity of dCpf1 cytidine base editors

Cas12a-linked base editors can broaden the targeting scope of programmable cytidine deaminases. Here the authors assess their target specificity in an in vitro genome-wide assay.

Daesik Kim
Kayeong Lim
Jin-Soo Kim
ResearchOpen Access13 Aug 2020
Nature Communications

Volume: 11, P: 1-8
Role of gut-derived bacterial lipopolysaccharide and peripheral TLR4 in immobilization stress-induced itch aggravation in a mouse model of atopic dermatitis

Da-Eun Cho
Joon-Pyo Hong
Dae-Hyun Hahm
ResearchOpen Access15 Mar 2024
Scientific Reports

Volume: 14, P: 1-16
Correction: PLK1/vimentin signaling facilitates immune escape by recruiting Smad2/3 to PD-L1 promoter in metastatic lung adenocarcinoma

Hay-Ran Jang
Sol-Bi Shin
Hyungshin Yim
Amendments and CorrectionsOpen Access17 Aug 2021
Cell Death & Differentiation

Volume: 29, P: 2106
PLK1/vimentin signaling facilitates immune escape by recruiting Smad2/3 to PD-L1 promoter in metastatic lung adenocarcinoma

Hay-Ran Jang
Sol-Bi Shin
Hyungshin Yim
ResearchOpen Access07 May 2021
Cell Death & Differentiation

Volume: 28, P: 2745-2764
Effect of desalted Salicornia europaea L. ethanol extract (PM-EE) on the subjects complaining memory dysfunction without dementia: a 12 week, randomized, double-blind, placebo-controlled clinical trial

Woo-Jin Lee
Yong-Won Shin
Manho Kim
ResearchOpen Access16 Nov 2020
Scientific Reports

Volume: 10, P: 1-12
Mitotic protein kinase-driven crosstalk of machineries for mitosis and metastasis

Chang-Hyeon Kim
Da-Eun Kim
Hyungshin Yim
ReviewsOpen Access04 Apr 2022
Experimental & Molecular Medicine

Volume: 54, P: 414-425