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Showing 1–19 of 19 results
Advanced filters: Author: Dominique Bergmann Clear advanced filters

  • Genomic analyses applied to 14 childhood- and adult-onset psychiatric disorders identifies five underlying genomic factors that explain the majority of the genetic variance of the individual disorders.

    • Andrew D. Grotzinger
    • Josefin Werme
    • Jordan W. Smoller
    ResearchOpen Access
    Nature
    Volume: 649, P: 406-415

  • Timothy Frayling, Joel Hirschhorn, Peter Visscher and colleagues report a meta-analysis of genome-wide association studies for adult height in 253,288 individuals. They identify 697 variants in 423 loci significantly associated with adult height and find that these variants cluster in pathways involved in growth and together explain one-fifth of the heritability for this trait.

    • Andrew R Wood
    • Tonu Esko
    • Timothy M Frayling
    Research
    Nature Genetics
    Volume: 46, P: 1173-1186

  • Exploring genomic data from contemporary and 191 Arabidopsis thaliana herbarium specimens collected over 193 years, the authors identify signs of local adaptation in regulators of stomatal development in contemporary samples from different geographic regions, then use functional scoring to identify a genetic component contributing to this change.

    • Patricia L. M. Lang
    • Joel M. Erberich
    • Dominique C. Bergmann
    ResearchOpen Access
    Nature Ecology & Evolution
    Volume: 8, P: 1641-1653

  • A set of three paralogous bHLH transcription factors is required to promote stomatal development. SPEECHLESS, MUTE and FAMA are sequentially expressed in, and are successively required for, the initiation, proliferation and terminal differentiation of cells in the stomatal lineage.

    • Cora A. MacAlister
    • Kyoko Ohashi-Ito
    • Dominique C. Bergmann
    Research
    Nature
    Volume: 445, P: 537-540

  • Two genes controlling the transcriptional network involved in stomatal development in Arabidopsis thaliana have a conserved function in the non-vascular moss Physcomitrella patens. Moss mutants without stomata show delayed capsule dehiscence.

    • Caspar C. Chater
    • Robert S. Caine
    • David J. Beerling
    Research
    Nature Plants
    Volume: 2, P: 1-7

  • Stem-cell-specific genes regulate processes such as maintenance, identity and/or division. Here, the authors show that in the Arabidopsis root TCX2, a gene expressed across different stem cell populations (a stem-cell-ubiquitous gene), controls division and identity by regulating stem-cell-type-specific networks.

    • Natalie M. Clark
    • Eli Buckner
    • Rossangela Sozzani
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-11

  • Data from over 700,000 individuals reveal the identity of 83 sequence variants that affect human height, implicating new candidate genes and pathways as being involved in growth.

    • Eirini Marouli
    • Mariaelisa Graff
    • Guillaume Lettre
    Research
    Nature
    Volume: 542, P: 186-190

  • This very large genome-wide association study identifies hundreds of new genetic variants influencing adult height in at least 180 loci enriched for genes involved in skeletal growth defects. The results show that the likely causal gene is often located near the most strongly associated variant, that many loci have multiple independently associated variants and that associated variants are enriched for likely functional effects on genes.

    • Hana Lango Allen
    • Karol Estrada
    • Joel N. Hirschhorn
    Research
    Nature
    Volume: 467, P: 832-838

  • This Review aims to define an updated nomenclature for plasma membrane domains in plants. The authors are experts in this field who unite here in an effort to eliminate the ambiguities and confusion that have persisted until now.

    • Yvon Jaillais
    • Emmanuelle Bayer
    • Julien Gronnier
    Reviews
    Nature Plants
    Volume: 10, P: 1172-1183

  • Using whole-genome data for single-nucleotide polymorphism and results from genome-wide association studies, the authors show that people’s preference for pairing with those with similar phenotypic traits has genetic causes and consequences.

    • Matthew R. Robinson
    • Aaron Kleinman
    • Peter M. Visscher
    Research
    Nature Human Behaviour
    Volume: 1, P: 1-13

  • In this Perspective, Diane Dickel and colleagues review recent progress and opportunities in applying single-cell sequencing and microfluidics methods to plants. The authors highlight the need for new tools developed with plants in mind, and advocate for the creation of a centralized, open-access database to house plant single-cell data.

    • Benjamin Cole
    • Dominique Bergmann
    • Diane E. Dickel
    ReviewsOpen Access
    Communications Biology
    Volume: 4, P: 1-12