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Showing 101–150 of 188 results

Advanced filters: Author: Douglas A Levine Clear advanced filters

Author Correction: Combined burden and functional impact tests for cancer driver discovery using DriverPower

Shimin Shuai
Federico Abascal
Christian von Mering
Amendments and CorrectionsOpen Access08 Dec 2022
Nature Communications

Volume: 13, P: 1
Author Correction: Divergent mutational processes distinguish hypoxic and normoxic tumours

Vinayak Bhandari
Constance H. Li
Christian von Mering
Amendments and CorrectionsOpen Access08 Dec 2022
Nature Communications

Volume: 13, P: 1
Truncating mutation in the autophagy gene UVRAG confers oncogenic properties and chemosensitivity in colorectal cancers

Some colon carcinomas with microsatellite instability carry a frameshift mutation in a tumour suppressor UVRAG. Here the authors show that mutant UVRAG triggers colorectal cancer by antagonizing the activity of normal UVRAG in autophagy and chromosomal stability, but also sensitizes the cancer to DNA damage-inducing chemotherapeutic drugs.

Shanshan He
Zhen Zhao
Chengyu Liang
ResearchOpen Access03 Aug 2015
Nature Communications

Volume: 6, P: 1-14
Author Correction: Pathway and network analysis of more than 2500 whole cancer genomes

Matthew A. Reyna
David Haan
Christian von Mering
Amendments and CorrectionsOpen Access08 Dec 2022
Nature Communications

Volume: 13, P: 1
Author Correction: Pan-cancer analysis of whole genomes

Lauri A. Aaltonen
Federico Abascal
Christian von Mering
Amendments and CorrectionsOpen Access25 Jan 2023
Nature

Volume: 614, P: E39
Author Correction: The repertoire of mutational signatures in human cancer

Ludmil B. Alexandrov
Jaegil Kim
Christian von Mering
Amendments and CorrectionsOpen Access25 Jan 2023
Nature

Volume: 614, P: E41
Author Correction: Genomic basis for RNA alterations in cancer

Claudia Calabrese
Natalie R. Davidson
Christian von Mering
Amendments and CorrectionsOpen Access25 Jan 2023
Nature

Volume: 614, P: E37
Author Correction: Genomic footprints of activated telomere maintenance mechanisms in cancer

Lina Sieverling
Chen Hong
Christian von Mering
Amendments and CorrectionsOpen Access08 Dec 2022
Nature Communications

Volume: 13, P: 1
Author Correction: Integrative pathway enrichment analysis of multivariate omics data

Marta Paczkowska
Jonathan Barenboim
Christian von Mering
Amendments and CorrectionsOpen Access08 Dec 2022
Nature Communications

Volume: 13, P: 1
Author Correction: High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations

Yiqun Zhang
Fengju Chen
Christian von Mering
Amendments and CorrectionsOpen Access08 Dec 2022
Nature Communications

Volume: 13, P: 1
Author Correction: Inferring structural variant cancer cell fraction

Marek Cmero
Ke Yuan
Christian von Mering
Amendments and CorrectionsOpen Access08 Dec 2022
Nature Communications

Volume: 13, P: 1
Author Correction: The evolutionary history of 2,658 cancers

Moritz Gerstung
Clemency Jolly
Christian von Mering
Amendments and CorrectionsOpen Access25 Jan 2023
Nature

Volume: 614, P: E42
Author Correction: Patterns of somatic structural variation in human cancer genomes

Yilong Li
Nicola D. Roberts
Christian von Mering
Amendments and CorrectionsOpen Access25 Jan 2023
Nature

Volume: 614, P: E38
A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24

Simon Gayther and colleagues report a genome wide association study for ovarian cancer. They identify two new susceptibility loci at 2q31 and 8q24 and two suggestive susceptibility loci at 3q25 and 17q21.

Ellen L Goode
Georgia Chenevix-Trench
Paul D P Pharoah
Research19 Sept 2010
Nature Genetics

Volume: 42, P: 874-879
Integrated genomic and molecular characterization of cervical cancer

This paper describes molecular subtypes of cervical cancers, including squamous cell carcinoma and adenocarcinoma clusters defined by HPV status and molecular features, and distinct molecular pathways that are activated in cervical carcinomas caused by different somatic alterations and HPV types.

Robert D. Burk
Zigui Chen
David Mutch
ResearchOpen Access23 Jan 2017
Nature

Volume: 543, P: 378-384
The rapid destabilization of p53 mRNA in immortal chicken embryo fibroblast cells

Hyunggee Kim
Seungkwon You
Douglas N Foster
Research28 Aug 2001
Oncogene

Volume: 20, P: 5118-5123
A role for genes in the ‘caregiver stress process’?

Douglas A. Wolf
Frank A. Middleton
ResearchOpen Access22 Oct 2018
Translational Psychiatry

Volume: 8, P: 1-10
Daratumumab plus lenalidomide maintenance in newly diagnosed multiple myeloma after transplant: AURIGA subgroup analyses

Laahn Foster
Larry D. Anderson Jr
Ashraf Badros
ResearchOpen Access06 Oct 2025
Blood Cancer Journal

Volume: 15, P: 1-10
Author Correction: Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples

Matthew H. Bailey
William U. Meyerson
Christian von Mering
Amendments and CorrectionsOpen Access30 Nov 2020
Nature Communications

Volume: 11, P: 1
Characterizing prostate cancer risk through multi-ancestry genome-wide discovery of 187 novel risk variants

A multi-ancestry genome-wide association study of prostate cancer performed in 156,319 cases and 788,443 controls identifies 187 novel risk variants associated with the disease. Genetic risk scores associated with overall risk, and risk of aggressive disease in men of African ancestry.

Anqi Wang
Jiayi Shen
Christopher A. Haiman
Research09 Nov 2023
Nature Genetics

Volume: 55, P: 2065-2074
Polygenic risk modeling for prediction of epithelial ovarian cancer risk

Eileen O. Dareng
Jonathan P. Tyrer
Paul D. P. Pharoah
ResearchOpen Access14 Jan 2022
European Journal of Human Genetics

Volume: 30, P: 349-362
Proteogenomic characterization of human colon and rectal cancer

Proteome analysis of The Cancer Genome Atlas (TCGA) colorectal cancer specimens reveals that DNA- or RNA-level measurements cannot reliably predict protein abundance, colorectal tumours can be separated into distinct proteotypes, and that copy number alterations drive mRNA abundance changes but few extend to protein-level changes.

Bing Zhang
Jing Wang
R. Reid Townsend
Research20 Jul 2014
Nature

Volume: 513, P: 382-387
A genome-wide association study identifies new susceptibility loci for esophageal adenocarcinoma and Barrett's esophagus

Thomas Vaughan and colleagues report a genome-wide association study of esophageal adenocarcinoma together with its precancerous lesion, Barrett's esophagus. They identified three loci associated with susceptibility to this cancer.

David M Levine
Weronica E Ek
Thomas L Vaughan
Research13 Oct 2013
Nature Genetics

Volume: 45, P: 1487-1493
Outcomes of teclistamab in patients with relapsed/refractory multiple myeloma with prior exposure to BCMA-directed therapy: a multicenter study from the U.S. Multiple Myeloma Immunotherapy Consortium

Danai Dima
Mariola A. Vazquez-Martinez
Leyla Shune
ResearchOpen Access25 Jun 2025
Blood Cancer Journal

Volume: 15, P: 1-9
Incomplete inhibition of the Rb tumor suppressor pathway in the context of inactivated p53 is sufficient for pancreatic islet tumorigenesis

Oriol Casanovas
Jeffrey H Hager
Douglas Hanahan
Research27 Jun 2005
Oncogene

Volume: 24, P: 6597-6604
Differences in DNA binding properties between E2F1 and E2F4 specify repression of the Mcl-1 promoter

Rhonda Croxton
Yihong Ma
W Douglas Cress
Research27 Feb 2002
Oncogene

Volume: 21, P: 1563-1570
Identification of the Target Cells of Orientia tsutsugamushi in Human Cases of Scrub Typhus

Cecilia G Moron
Vsevolod L Popov
David H Walker
Research01 Aug 2001
Modern Pathology

Volume: 14, P: 752-759
Knockdown of p53 levels in human keratinocytes accelerates Mcl-1 and Bcl-x_L reduction thereby enhancing UV-light induced apoptosis

Vijaya Chaturvedi
Leonid A Sitailo
Brian J Nickoloff
Research06 Jun 2005
Oncogene

Volume: 24, P: 5299-5312
Evaluation of the Effectiveness of the Standardized Neonatal Resuscitation Program

Nalini Singhal
Douglas D McMillan
Y Jean Yee
Research03 Oct 2001
Journal of Perinatology

Volume: 21, P: 388-392
Outcomes of elderly patients with relapsed refractory multiple myeloma (RRMM) treated with teclistamab: a multicenter study from the U.S. Multiple Myeloma Immunotherapy Consortium

Oren Pasvolsky
Danai Dima
Ariel Grajales-Cruz
ResearchOpen Access09 May 2025
Blood Cancer Journal

Volume: 15, P: 1-6
The Effect of Monosaturated and Polyunsaturated Fatty Acids on Oxygen Toxicity in Cultured Cells

Douglas R Spitz
Michael T Kinter
Robert J Roberts
Research01 Sept 1992
Pediatric Research

Volume: 32, P: 366-372
Rethinking ovarian cancer II: reducing mortality from high-grade serous ovarian cancer

This Opinion article outlines a set of research priorities, based on discussions held at the 2015 Helene Harris Memorial Trust Ovarian Cancer Action meeting, that the authors believe will reduce incidence and improve outcomes for women with high-grade serous ovarian cancer.

David D. Bowtell
Steffen Böhm
Frances R. Balkwill
Reviews23 Oct 2015
Nature Reviews Cancer

Volume: 15, P: 668-679
Publisher Correction: Shared heritability and functional enrichment across six solid cancers

Xia Jiang
Hilary K. Finucane
Sara Lindström
Amendments and CorrectionsOpen Access23 Sept 2019
Nature Communications

Volume: 10, P: 1-8
The Effects of Early Rearing Environment on the Development of GABA_A and Central Benzodiazepine Receptor Levels and Novelty-Induced Fearfulness in the Rat

Christian Caldji
Darlene Francis
Michael J Meaney
Research01 Mar 2000
Neuropsychopharmacology

Volume: 22, P: 219-229
Rethinking ovarian cancer: recommendations for improving outcomes

This Opinion article outlines nine major recommendations for improving our understanding of ovarian cancer and the outcomes of women with this group of diseases.

Sebastian Vaughan
Jermaine I. Coward
Frances R. Balkwill
Reviews23 Sept 2011
Nature Reviews Cancer

Volume: 11, P: 719-725
Direct repression of the Mcl-1 promoter by E2F1

Rhonda Croxton
Yihong Ma
W Douglas Cress
Research21 Feb 2002
Oncogene

Volume: 21, P: 1359-1369
Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer

The analysis of T-cell antigens in long-term survivors of pancreatic ductal adenocarcinoma suggests that neoantigen immunogenicity and quality, not purely quantity, correlate with survival.

Vinod P. Balachandran
Marta Łuksza
Steven D. Leach
Research01 Nov 2017
Nature

Volume: 551, P: 512-516
1686 CHANGES IN MEAN AIRWAY PRESSURE: SIGNIFICANCE IN NEONATAL AIRLEAK SYNDROME

Millard A Litzenberger
H Douglas Cunningham
Jacqueline A Noonan
Research01 Apr 1981
Pediatric Research

Volume: 15, P: 724
Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus

Peter Donnelly and colleagues report a genome-wide association study for Barrett's esophagus, a common premalignant condition associated with stomach acid reflux and predisposing to esophageal adenocarcinoma. They identify two loci associated with susceptibility to Barrett's esophagus.

Zhan Su
Laura J Gay
Janusz A Z Jankowski
Research09 Sept 2012
Nature Genetics

Volume: 44, P: 1131-1136
Resistance to therapy caused by intragenic deletion in BRCA2

Stacey L. Edwards
Rachel Brough
Alan Ashworth
Research10 Feb 2008
Nature

Volume: 451, P: 1111-1115
Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles

Dysregulated autophagy is associated with a variety of conditions, including cancer, neurodegenerative diseases, cardiovascular disorders and infectious diseases. However, despite significant efforts, no specific modulators of autophagy have yet been moved into the clinic. Here, Galluzziet al. discuss the therapeutic potential of autophagy modulators and consider the key challenges that have limited their development.

Lorenzo Galluzzi
José Manuel Bravo-San Pedro
Guido Kroemer
Reviews19 May 2017
Nature Reviews Drug Discovery

Volume: 16, P: 487-511
Evaluation of an augmented reality platform for austere surgical telementoring: a randomized controlled crossover study in cricothyroidotomies

Edgar Rojas-Muñoz
Chengyuan Lin
Juan P. Wachs
ResearchOpen Access21 May 2020
npj Digital Medicine

Volume: 3, P: 1-9
Defining a ‘cells to society’ research framework for appendiceal tumours

In this Expert Recommendation, Holowatyj et al. cover the current state of the field in appendiceal cancer, including the distinct challenges involved in studying this rare tumour type, and propose a conceptual research framework to facilitate discoveries that will advance knowledge of appendix carcinogenesis and metastasis to deliver better outcomes for patients.

Andreana N. Holowatyj
Michael J. Overman
Deborah Shelton
Reviews20 Feb 2025
Nature Reviews Cancer

Volume: 25, P: 293-315
Safety and Efficacy of Human Growth Hormone (rhGH) in Children with Growth Failure after Cardiac Transplantation

B Softness
G S Aranoff
L J Addonizio
Research01 Apr 1999
Pediatric Research

Volume: 45, P: 31
Absolute quantification of somatic DNA alterations in human cancer

Tumors vary in their ratio of normal to cancerous cells and in their genomic copy number. Carter et al. describe an analytic method for inferring the purity and ploidy of a tumor sample, enabling longitudinal studies of subclonal mutations and tumor evolution.

Scott L Carter
Kristian Cibulskis
Gad Getz
Research29 Apr 2012
Nature Biotechnology

Volume: 30, P: 413-421
The Newborn of Diabetic Rat. I. Hormonal and Metabolic Changes in the Postnatal Period

Jose M Cuezva
Edward S Burkett
Mulchand S Patel
Research01 Aug 1982
Pediatric Research

Volume: 16, P: 632-637
The importance of p53 pathway genetics in inherited and somatic cancer genomes

Using genomic data, this Analysis demonstrates that commonly inherited single nucleotide polymorphisms (SNPs) occurring in genes of the p53 pathway affect the incidence of a broad range of cancers, more so than SNPs in other pathways. This has implications for p53-mediated tumour suppression in humans.

Giovanni Stracquadanio
Xuting Wang
Gareth L. Bond
Research24 Mar 2016
Nature Reviews Cancer

Volume: 16, P: 251-265
A Short Polypeptide Marker Sequence Useful for Recombinant Protein Identification and Purification

Thomas P. Hopp
Kathryn S. Prickett
Paul J. Conlon
Research01 Oct 1988
Bio/Technology

Volume: 6, P: 1204-1210
QTc Interval in Infants Receiving Cisapride

Satbir Chhina
Ricardo L Peverini
Nidia R Vyhmeister
Research27 Feb 2002
Journal of Perinatology

Volume: 22, P: 144-148
The Neuropeptide Y (NPY) Y1 Receptor Subtype Mediates NPY-induced Antidepressant-like Activity in the Mouse Forced Swimming Test

John P Redrobe
Yvan Dumont
Rémi Quirion
Research08 Nov 2001
Neuropsychopharmacology

Volume: 26, P: 615-624

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