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Showing 101–150 of 191 results

Advanced filters: Author: Edwin C. Oh Clear advanced filters

microbeMASST: a taxonomically informed mass spectrometry search tool for microbial metabolomics data

microbeMASST is a tool to associate known and unknown metabolites to microbial producers leveraging untargeted metabolomics data.

Simone Zuffa
Robin Schmid
Pieter C. Dorrestein
ResearchOpen Access05 Feb 2024
Nature Microbiology

Volume: 9, P: 336-345
Deep-coverage whole genome sequences and blood lipids among 16,324 individuals

Common genetic variants associated with plasma lipids have been extensively studied for a better understanding of common diseases. Here, the authors use whole-genome sequencing of 16,324 individuals to analyze rare variant associations and to determine their monogenic and polygenic contribution to lipid traits.

Pradeep Natarajan
Gina M. Peloso
Sebastian Zoellner
ResearchOpen Access23 Aug 2018
Nature Communications

Volume: 9, P: 1-12
Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries

Circulating lipoprotein(a) is an important risk factor for cardiovascular disease and shows variability between different ethnic groups. Here, Zekavat et al. perform whole-genome sequencing in individuals of European and African ancestries and find ancestry-specific genetic determinants for lipoprotein(a) levels.

Seyedeh M. Zekavat
Sanni Ruotsalainen
Sebastian Zoellner
ResearchOpen Access04 Jul 2018
Nature Communications

Volume: 9, P: 1-14
COMPARISON OF MEASURED AND CALCUIATED SERUM BILIRUBIN BINDING CAPACITY (BBC)-A DANGER EXPOSED

Catherine M P Kierney
Eugene Ainbender
Jeffrey A Whitsett
Research01 Apr 1977
Pediatric Research

Volume: 11, P: 536
Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31

Most confirmed susceptibility variants for epithelial ovarian cancer lie in non-protein-coding sequences. Here Permuth-Wey and colleagues investigate variants in 3′ untranslated regions (UTRs) and uncover a new susceptibility locus.

Jennifer Permuth-Wey
Kate Lawrenson
Simon A. Gayther
ResearchOpen Access27 Mar 2013
Nature Communications

Volume: 4, P: 1-12
Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer

HNF1B is overexpressed in the clear cell subtype and epigenetically silenced in the serous subtype of ovarian cancer. Pearce and colleagues now show that genetic variants in HNF1B are differentially associated with risks of developing these two cancer subtypes, possibly through an epigenetic mechanism.

Hui Shen
Brooke L. Fridley
Celeste Leigh Pearce
ResearchOpen Access27 Mar 2013
Nature Communications

Volume: 4, P: 1-10
Thermodynamic, isotherm and kinetic studies lead ions adsorption onto Manihot esculenta chaff surface

Ali El-Rayyes
Ibrahim Arogundade
Ezekiel Folorunso Sodiya
ResearchOpen Access29 Jul 2025
Scientific Reports

Volume: 15, P: 1-21
Preclinical evaluation of ribociclib and its synergistic effect in combination with alpelisib in non-keratinizing nasopharyngeal carcinoma

Chi-Hang Wong
Brigette B. Y. Ma
Anthony T. C. Chan
ResearchOpen Access22 May 2018
Scientific Reports

Volume: 8, P: 1-8
Cellulose nanofibrils and silver nanoparticles enhances the mechanical and antimicrobial properties of polyvinyl alcohol nanocomposite film

Edwin Shigwenya Madivoli
Patrick Gachoki Kareru
Mostafa M. Elbagoury
ResearchOpen Access08 Nov 2022
Scientific Reports

Volume: 12, P: 1-13
Clinical genomic profiling in the management of patients with soft tissue and bone sarcoma

Comprehensive molecular profiles are required to understand and treat sarcomas, which comprise more than 70 different subtypes. Here, the authors profile the genomic landscape of 7494 sarcomas across 44 histologies using targeted panel sequencing and identify potential therapeutic targets.

Mrinal M. Gounder
Narasimhan P. Agaram
Dexter X. Jin
ResearchOpen Access15 Jun 2022
Nature Communications

Volume: 13, P: 1-15
Lower-body parkinsonism: reconsidering the threshold for external lumbar drainage

This Case Study describes a 80-year-old patient with lower-body parkinsonism who was diagnosed with vascular parkinsonism on the basis of clinical and neuroimaging findings, but whose gait and, to a lesser extent, cognitive impairments improved following external lumbar drainage. Postmortem neuropathology confirmed a diagnosis of normal pressure hydrocephalus.

Alberto J Espay
Raj K Narayan
Gabrielle de Courten-Myers
Reviews01 Jan 2008
Nature Clinical Practice Neurology

Volume: 4, P: 50-55
Nde1-mediated inhibition of ciliogenesis affects cell cycle re-entry

Ciliogenesis starts as cells enter quiescence and primary cilium resorption precedes mitosis. The centrosomal protein Nde1 is shown to regulate cilia length during the cell cycle. Loss of Nde1 in zebrafish leads to developmental patterning defects reflecting impaired control of cilium formation.

Sehyun Kim
Norann A. Zaghloul
Leonidas Tsiokas
Research13 Mar 2011
Nature Cell Biology

Volume: 13, P: 351-360
Durability of single-dose HPV vaccination in young Kenyan women: randomized controlled trial 3-year results

In a prespecified 3-year analysis of the KEN SHE trial, single-dose HPV vaccination was shown to be well tolerated and provided durable protection against cervical HPV infection in Kenyan women aged 15–20 years.

Ruanne V. Barnabas
Elizabeth R. Brown
Torin T. Schaafsma
ResearchOpen Access04 Dec 2023
Nature Medicine

Volume: 29, P: 3224-3232
Gene expression elucidates functional impact of polygenic risk for schizophrenia

The CommonMind Consortium sequenced RNA from dorsolateral prefrontal cortex of subjects with schizophrenia (N = 258) and control subjects (N = 279), creating a resource of gene expression and its genetic regulation. Using this resource, they found that ∼20% of schizophrenia loci have variants that may contribute to altered gene expression and liability.

Menachem Fromer
Panos Roussos
Pamela Sklar
Research26 Sept 2016
Nature Neuroscience

Volume: 19, P: 1442-1453
A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response

A high-resolution reference panel based on whole-genome sequencing data enables accurate imputation of HLA alleles across diverse populations and fine-mapping of HLA association signals for HIV-1 host response.

Yang Luo
Masahiro Kanai
Soumya Raychaudhuri
Research05 Oct 2021
Nature Genetics

Volume: 53, P: 1504-1516
GROWTH HORMONE RELEASING FACTOR GENE STRUCTURE IN GROWTH HORMONE DEFICIENCY

John S Parks
Laura C Sexton
John A Phillips III
Research01 Apr 1984
Pediatric Research

Volume: 18, P: 172
AORTIC CONTRAST ECHOCARDIOGRAM AND LA/AO RATIO IN THE DIAGNOSIS OF PATENT DUCTUS ARTERIOSUS

Edwin Soto
Nakul Chandra
Thomas Hegyi
Research01 Apr 1984
Pediatric Research

Volume: 18, P: 130
The normal oxygen consumption and respiratory quotient of the mammalian fetus

Elizabeth J James
John R Raye
Frederick C Battaglia
Research01 Aug 1971
Pediatric Research

Volume: 5, P: 419
Gβγs and the Ras binding domain of p110γ are both important regulators of PI3Kγ signalling in neutrophils

Sabine Suire
Alison M. Condliffe
Len Stephens
Research15 Oct 2006
Nature Cell Biology

Volume: 8, P: 1303-1309
Synergistic effects of nanosecond pulsed plasma and electric field on inactivation of pancreatic cancer cells in vitro

Edwin A. Oshin
Zobia Minhas
Chunqi Jiang
ResearchOpen Access09 Jan 2024
Scientific Reports

Volume: 14, P: 1-12
Bone metabolism during strict head-down tilt bed rest and exposure to elevated levels of ambient CO₂

Emily R. McGrath
Petra Frings-Meuthen
Sara R. Zwart
ResearchOpen Access16 Dec 2022
npj Microgravity

Volume: 8, P: 1-9
1348 IN-VIVO CALIBRATION IMPROVES THE RELIABILITY OF TRANSCUTANEOUS (Tc) OXYGEN MONITORING

Richard W Krouskop
Eresvita E Cabatu
Edwin G Brown
Research01 Apr 1981
Pediatric Research

Volume: 15, P: 668
Author Correction: GWAS of multiple neuropathology endophenotypes identifies new risk loci and provides insights into the genetic risk of dementia

Lincoln M. P. Shade
Yuriko Katsumata
David W. Fardo
Amendments and CorrectionsOpen Access17 Jun 2025
Nature Genetics

Volume: 57, P: 1788
Publisher Correction: GWAS of multiple neuropathology endophenotypes identifies new risk loci and provides insights into the genetic risk of dementia

Lincoln M. P. Shade
Yuriko Katsumata
David W. Fardo
Amendments and CorrectionsOpen Access17 Jun 2025
Nature Genetics

Volume: 57, P: 1791
Linking habitat preferences and fitness across scales for a relict bird species of the southern Andes

Tomás A. Altamirano
Fernando J. Novoa
José Tomás Ibarra
ResearchOpen Access06 Oct 2025
Scientific Reports

Volume: 15, P: 1-12
Oral 8-aminoguanine against age-related retinal degeneration

Oral treatment of a purine metabolite, 8-aminoguanine (8-AG) protects the retinal morphology and function during aging by mitigating hallmarks of aging, highlighting its potential in treating age-related retinal degeneration.

Abhishek Vats
Yibo Xi
Yuanyuan Chen
ResearchOpen Access26 May 2025
Communications Biology

Volume: 8, P: 1-18
The candidate tumour suppressor protein ING4 regulates brain tumour growth and angiogenesis

Igor Garkavtsev
Sergey V. Kozin
Rakesh K. Jain
Research18 Mar 2004
Nature

Volume: 428, P: 328-332
Brain and body energy metabolism and potential for treatment of psychiatric disorders

This Perspective highlights the important role of energy metabolism in psychiatric disorders and sets the groundwork for future studies in the emerging field of metabolic psychiatry.

Ana C. Andreazza
L. Felipe Barros
Corey Weistuch
Reviews25 Jun 2025
Nature Mental Health

Volume: 3, P: 763-771
Imprinting in the brain

A gene is considered to be imprinted if only the copy inherited from the mother or from the father is expressed throughout life. But one imprinted gene, Dlk1, disobeys this rule during postnatal neurodevelopment. See Letter p.381

Edwin C. Oh
Nicholas Katsanis
News & Views20 Jul 2011
Nature

Volume: 475, P: 299-300
A covalent chemical probe for Chikungunya nsP2 cysteine protease with antialphaviral activity and proteome-wide selectivity

Anirban Ghoshal
Edwin G. Tse
Timothy M. Willson
ResearchOpen Access01 Mar 2025
Scientific Reports

Volume: 15, P: 1-14
Human mitochondrial pyruvate carrier 2 as an autonomous membrane transporter

Raghavendra Sashi Krishna Nagampalli
José Edwin Neciosup Quesñay
Andre Luis Berteli Ambrosio
ResearchOpen Access22 Feb 2018
Scientific Reports

Volume: 8, P: 1-13
A comparative study of PCS and PAM50 prostate cancer classification schemes

Junhee Yoon
Minhyung Kim
Sungyong You
ResearchOpen Access02 Feb 2021
Prostate Cancer and Prostatic Diseases

Volume: 24, P: 733-742
Nano round polycrystalline adsorbent of chicken bones origin for Congo red dye adsorption

Edwin Andrew Ofudje
Khairia Mohammed Al-Ahmary
Abdullah G. Al-Sehemi
ResearchOpen Access02 Apr 2024
Scientific Reports

Volume: 14, P: 1-15
Redefining respiratory sinus arrhythmia as respiratory heart rate variability: an international Expert Recommendation for terminological clarity

The physiological phenomenon whereby heart rate varies in phase with breathing in vertebrates has been known as ‘respiratory sinus arrhythmia’. In this Expert Recommendation, the authors argue that this terminology is potentially misleading and propose replacing it with the term ‘respiratory heart rate variability’, which avoids pathological connotations.

Clément Menuet
Alona Ben-Tal
Alexander V. Gourine
Reviews06 May 2025
Nature Reviews Cardiology

Volume: 22, P: 978-984
Universal DNA methylation age across mammalian tissues

This study identifies and characterizes evolutionarily conserved cytosine methylation patterns related to age across mammals and establishes pan-mammalian epigenetic clocks.

A. T. Lu
Z. Fei
S. Horvath
ResearchOpen Access10 Aug 2023
Nature Aging

Volume: 3, P: 1144-1166
Evolution of SARS-CoV-2 spike trimers towards optimized heparan sulfate cross-linking and inter-chain mobility

Jurij Froese
Marco Mandalari
Kay Grobe
ResearchOpen Access31 Dec 2024
Scientific Reports

Volume: 14, P: 1-16
Proteins Associated with Cardiac Neural Crest in the Pharyngeal Region of Early Chick Embryos

Ra-Id Abdulla
Edwin F Slott
Margaret L Kirby
Research01 Jan 1993
Pediatric Research

Volume: 33, P: 43-47
Author Correction: Clonal haematopoiesis and risk of chronic liver disease

Waihay J. Wong
Connor Emdin
Pradeep Natarajan
Amendments and Corrections03 Jul 2023
Nature

Volume: 619, P: E47
Conspecific and heterospecific pheromones stimulate dispersal of entomopathogenic nematodes during quiescence

Fatma Kaplan
Abigail Perret-Gentil
David Shapiro-Ilan
ResearchOpen Access31 Mar 2020
Scientific Reports

Volume: 10, P: 1-12
Author Correction: Inherited causes of clonal haematopoiesis in 97,691 whole genomes

Alexander G. Bick
Joshua S. Weinstock
Pradeep Natarajan
Amendments and Corrections11 Mar 2021
Nature

Volume: 591, P: E27
DISC1-dependent switch from progenitor proliferation to migration in the developing cortex

Koko Ishizuka
Atsushi Kamiya
Akira Sawa
Research06 Apr 2011
Nature

Volume: 473, P: 92-96
KCTD13 is a major driver of mirrored neuroanatomical phenotypes of the 16p11.2 copy number variant

Overexpression of all 29 human transcripts of a region of the 16p11.2 chromosome in zebrafish embryos identifies KCTD13 as the message inducing the microcephaly phenotype associated with 16p11.2 duplication, whereas its suppression yields the macrocephalic phenotype associated with the reciprocal deletion, suggesting that KCTD13 is a major driver for the neurodevelopmental phenotypes associated with the 16p11.2 copy number variants.

Christelle Golzio
Jason Willer
Nicholas Katsanis
Research16 May 2012
Nature

Volume: 485, P: 363-367
Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis

Michael Cho and colleagues report a genome-wide association study of risk for chronic obstructive pulmonary disease (COPD) in a large, multi-ancestry cohort. They identify 22 genome-wide significant loci, including 13 not previously associated with COPD and 4 not previously associated with any lung function trait.

Brian D Hobbs
Kim de Jong
Michael H Cho
Research06 Feb 2017
Nature Genetics

Volume: 49, P: 426-432
Author Correction: Universal DNA methylation age across mammalian tissues

A. T. Lu
Z. Fei
S. Horvath
Amendments and CorrectionsOpen Access06 Sept 2023
Nature Aging

Volume: 3, P: 1462
Toughness amplification in copper/epoxy joints through pulsed laser micro-machined interface heterogeneities

Edwin Hernandez
Marco Alfano
Gilles Lubineau
ResearchOpen Access27 Nov 2017
Scientific Reports

Volume: 7, P: 1-12
Shigella virulence protein VirG is a broadly protective antigen and vaccine candidate

Girmay Desalegn
Chitradevi S. Tamilselvi
Marcela F. Pasetti
ResearchOpen Access02 Jan 2024
npj Vaccines

Volume: 9, P: 1-11
Host-Guest Self-assembly in Block Copolymer Blends

Woon Ik Park
YongJoo Kim
Yeon Sik Jung
ResearchOpen Access12 Nov 2013
Scientific Reports

Volume: 3, P: 1-10
Outdoor malaria vector species profile in dryland ecosystems of Kenya

Fiona Kinya
Clifford M. Mutero
David P. Tchouassi
ResearchOpen Access03 May 2022
Scientific Reports

Volume: 12, P: 1-10
A loss of function variant in AGPAT3 underlies intellectual disability and retinitis pigmentosa (IDRP) syndrome

Madiha Amin Malik
Muhammad Arif Nadeem Saqib
Muhammad Ansar
Research11 Oct 2023
European Journal of Human Genetics

Volume: 31, P: 1447-1454
Strain-dependence of the Angelman Syndrome phenotypes in Ube3a maternal deficiency mice

Heather A. Born
An T. Dao
Anne E. Anderson
ResearchOpen Access16 Aug 2017
Scientific Reports

Volume: 7, P: 1-15

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