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Experimental & Molecular Medicine (2)
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Showing 1–6 of 6 results

Advanced filters: Author: Fengdong Zhao Clear advanced filters

Pla2g7 regulates bone homeostasis via Alox12/12-HETE/Gpr31 signaling axis

Pla2g7 is a secreted enzyme mainly produced by myeloid cells and exerts a significant role in a spectrum of metabolic and inflammatory disorders. Here they show that Pla2g7 expression is enriched in osteoclasts and is associated with bone resorption, revealing an important role in bone homeostasis.

Jiayan Jin
Zeyu Zheng
Jian Chen
ResearchOpen Access10 Dec 2025
Nature Communications

Volume: 16, P: 1-19
RKIP regulates bone marrow macrophage differentiation to mediate osteoclastogenesis and H-type vessel formation

Differentiation of bone niche macrophages regulates bone homeostasis. Here the authors show that Raf kinase inhibitor protein RKIP regulates differentiation of bone niche macrophages to mediate osteoclastogenesis and H-type vessel formation.

Zeyu Zheng
Siyue Tao
Fengdong Zhao
ResearchOpen Access15 Aug 2025
Nature Communications

Volume: 16, P: 1-17
Mrgprb2-mediated mast cell activation exacerbates Modic changes by regulating immune niches

Zhongyin Ji
Jie Li
Fengdong Zhao
ResearchOpen Access01 May 2024
Experimental & Molecular Medicine

Volume: 56, P: 1178-1192
Multiomics identify the gene expression signature of the spinal cord during aging process

Multiomics sheds light on the gene expression signature of the spinal cord during the ageing process-resistance to ferroptosis via the upregulation of Fth1.

Lintao Xu
Jingyu Wang
Ying-ying Chen
ResearchOpen Access07 Feb 2025
Communications Biology

Volume: 8, P: 1-12
The RCAN1.4-calcineurin/NFAT signaling pathway is essential for hypoxic adaption of intervertebral discs

Bao Huang
Yongqing He
Fengdong Zhao
ResearchOpen Access29 May 2020
Experimental & Molecular Medicine

Volume: 52, P: 865-875
Site-1 protease controls osteoclastogenesis by mediating LC3 transcription

Zeyu Zheng
Xuyang Zhang
Jian Chen
Research19 Jan 2021
Cell Death & Differentiation

Volume: 28, P: 2001-2018