Nature Search

Chemistry-informed deep learning model for predicting stereoselectivity and absolute configuration in asymmetric hydrogenation

This study introduces ChemAHNet, a deep learning model that predicts stereoselectivity and absolute configurations in the asymmetric hydrogenation of olefins with two prochiral centers, providing a broadly applicable tool for catalyst and substrate design.

Li Cheng
Pan-Lin Shao
Bo Zhang
Research05 Dec 2025
Nature Computational Science

P: 1-11
The CLASSY family controls tissue-specific DNA methylation patterns in Arabidopsis

CLASSY (CLSY) proteins regulate DNA methylation at specific loci in the Arabidopsis genome. Here the authors show that the CLSYs also control tissue-specific DNA methylation, including at siren loci in ovules, and that the lack of an individual CLSYs can shift the epigenetic landscape between tissues.

Ming Zhou
Ceyda Coruh
Julie A. Law
ResearchOpen Access11 Jan 2022
Nature Communications

Volume: 13, P: 1-16
Histone acetyltransferase 1 promotes postinfarction inflammatory response by regulation of monocyte histone succinylation

Myocardial infarction triggers inflammation driven by immune cell reprogramming, but the epigenetic regulators involved remain unclear. Here, the authors show that histone acetyltransferase 1 enhances postinfarction inflammation by promoting histone succinylation in monocytes.

Yutong Guo
Jie Xiong
Yingfeng Tu
ResearchOpen Access28 Nov 2025
Nature Communications

Volume: 16, P: 1-22
Chromosomal-level genome assembly of two dominant desert shrub species in Haloxylon (Amaranthaceae)

Fang Yang
Di Gao
Guanghui Lv
ResearchOpen Access30 Dec 2025
Scientific Data

P: 1-8
Cold-induced FOXO1 nuclear transport aids cold survival and tissue storage

How tissues adapt to extreme cold is not well understood. Here, the authors discover a mechanism that promotes FOXO1-mediated cold survival gene transcription at low temperatures, with potential implications for long-term tissue storage for transplantation.

Xiaomei Zhang
Lihao Ge
Jingxing Ou
ResearchOpen Access03 Apr 2024
Nature Communications

Volume: 15, P: 1-17
DNMT1 modulation of RASSF1A methylation enhances breast cancer brain metastasis

Qianqian Cao
Gongwen Xu
Xiaomei Li
ResearchOpen Access11 Dec 2025
Cell Death & Disease

Volume: 17, P: 1-16
Knockdown of EGFR inhibits growth and invasion of gastric cancer cells

Y Zhen
L Guanghui
Z Xiefu
Research14 Nov 2014
Cancer Gene Therapy

Volume: 21, P: 491-497
Generation of whole tumor cell vaccine for on-demand manipulation of immune responses against cancer under near-infrared laser irradiation

Whole autologous tumor cell vaccine (TCV) has been proposed as a tool for cancer immunotherapy. Here the authors describe the design of a TCV platform based on photothermal nanoparticle-loaded tumor cells, triggering NIR laser irradiation induced anti-tumor immune responses at the vaccination site.

Jiaqi Meng
Yanlin Lv
Wei Wei
ResearchOpen Access26 Jul 2023
Nature Communications

Volume: 14, P: 1-17
Upregulation of MiR-205 transcriptionally suppresses SMAD4 and PTEN and contributes to human ovarian cancer progression

Juanni Li
Kuan Hu
Xiaoying Wu
ResearchOpen Access01 Feb 2017
Scientific Reports

Volume: 7, P: 1-9
Multiplexed discrimination of SARS-CoV-2 variants via plasmonic-enhanced fluorescence in a portable and automated device

A portable multiplexed assay allows for the rapid detection, via plasmonic-gold-enhanced near-infrared fluorescence, of SARS-CoV-2 RNA at single-copy sensitivity and single-nucleotide specificity for the discrimination of variants of the virus.

Ying Liu
Yang Yang
Bo Zhang
Research21 Sept 2023
Nature Biomedical Engineering

Volume: 7, P: 1636-1648
Role of GPX3+ astrocytes in breast cancer brain metastasis activated by circulating tumor cell exosomes

Guanghui Huang
Gongwen Xu
Xiaomei Li
ResearchOpen Access07 Mar 2025
npj Precision Oncology

Volume: 9, P: 1-19
Mangrove reforestation provides greater blue carbon benefit than afforestation for mitigating global climate change

Blue carbon benefit has not been compared among mangrove reforestation and afforestation pathways at the global scale. This study shows that mangrove reforestation could perform a greater carbon storage potential per hectare than afforestation as its higher nitrogen availability and lower salinity.

Shanshan Song
Yali Ding
Guanghui Lin
ResearchOpen Access10 Feb 2023
Nature Communications

Volume: 14, P: 1-11
Introgressing the Aegilops tauschii genome into wheat as a basis for cereal improvement

An introgression platform for transferring genetic variations of Aegilops tauschii to hexaploid wheat is established based on synthetic octoploid wheat. Combined with newly generated genome resources of A. tauschii, it represents a powerful tool for wheat gene discovery and breeding.

Yun Zhou
Shenglong Bai
Chun-Peng Song
Research27 May 2021
Nature Plants

Volume: 7, P: 774-786
Exosomes secreted from cardiomyocytes suppress the sensitivity of tumor ferroptosis in ischemic heart failure

Ye Yuan
Zhongting Mei
Baofeng Yang
ResearchOpen Access27 Mar 2023
Signal Transduction and Targeted Therapy

Volume: 8, P: 1-15
Histamine H3 receptors aggravate cerebral ischaemic injury by histamine-independent mechanisms

Histamine H3 receptor dysregulation is a hallmark of pathological conditions in the central nervous system, and H3 receptor antagonism is neuroprotective. Here Chen et al.show that histamine-independent H3 receptor activation can enhance neuronal cell death during cerebral ischaemia by suppressing autophagy.

Haijing Yan
Xiangnan Zhang
Zhong Chen
ResearchOpen Access25 Feb 2014
Nature Communications

Volume: 5, P: 1-12
FGF1^ΔHBS prevents diabetic cardiomyopathy by maintaining mitochondrial homeostasis and reducing oxidative stress via AMPK/Nur77 suppression

Dezhong Wang
Yuan Yin
Zhifeng Huang
ResearchOpen Access24 Mar 2021
Signal Transduction and Targeted Therapy

Volume: 6, P: 1-12
A multi-paradigm EEG dataset for studying upper limb rehabilitation exercises

Wenwen Chang
Weixuan Kong
Xuan Liu
ResearchOpen Access28 Nov 2025
Scientific Data

Volume: 12, P: 1-15
ZBTB16 inhibits DNA replication and induces cell cycle arrest by targeting WDHD1 transcription in lung adenocarcinoma

Kai Wang
Deyu Guo
Jiajun Du
Research23 Apr 2024
Oncogene

Volume: 43, P: 1796-1810
Evaluation of a micro/nanofluidic chip platform for diagnosis of central nervous system infections: a multi-center prospective study

Guanghui Zheng
Yan Zhang
Guojun Zhang
ResearchOpen Access31 Jan 2020
Scientific Reports

Volume: 10, P: 1-9
Kawasaki disease: ubiquitin-specific protease 5 promotes endothelial inflammation via TNFα-mediated signaling

Chengcheng Huang
Wang Wang
Haitao Lv
Research03 Nov 2022
Pediatric Research

Volume: 93, P: 1883-1890
Influence of aridity and salinity on plant nutrients scales up from species to community level in a desert ecosystem

Yanming Gong
Guanghui Lv
Jing Cao
ResearchOpen Access28 Jul 2017
Scientific Reports

Volume: 7, P: 1-12
Neutrophil heterogeneity in Kawasaki disease and multisystem inflammatory syndrome in children

Nana Wang
Ling Sun
Zhiheng Liu
Reviews19 Jun 2025
Pediatric Research

P: 1-12
Vitamin D sensitizes cervical cancer to radiation-induced apoptosis by inhibiting autophagy through degradation of Ambra1

Zhaoming zhang
Xinyue Yu
Guanghui Cheng
ResearchOpen Access04 Jan 2025
Cell Death Discovery

Volume: 11, P: 1-11
Study on the fastening characteristics of preformed helical fittings considering the surface effect of transmission lines

Lv Zhongbin
Liu Guanghui
Yan Bo
ResearchOpen Access06 Jul 2023
Scientific Reports

Volume: 13, P: 1-21
Indoleamine 2,3-dioxygenase 1 limits hepatic inflammatory cells recruitment and promotes bile duct ligation-induced liver fibrosis

Chan Mo
Shuwen Xie
Zhiping Lv
ResearchOpen Access07 Jan 2021
Cell Death & Disease

Volume: 12, P: 1-15
Impact of groundwater depth and soil salinity on riparian plant diversity and distribution in an arid area of China

Yong Zeng
Chengyi Zhao
Yan Li
ResearchOpen Access29 Apr 2020
Scientific Reports

Volume: 10, P: 1-10
Risk-prediction models for intravenous immunoglobulin resistance in Kawasaki disease: Risk-of-Bias Assessment using PROBAST

Shuhui Wang
Hongbiao Huang
Haitao Lv
ResearchOpen Access24 Mar 2023
Pediatric Research

Volume: 94, P: 1125-1135

Search

Chemistry-informed deep learning model for predicting stereoselectivity and absolute configuration in asymmetric hydrogenation

The CLASSY family controls tissue-specific DNA methylation patterns in Arabidopsis

Histone acetyltransferase 1 promotes postinfarction inflammatory response by regulation of monocyte histone succinylation

Chromosomal-level genome assembly of two dominant desert shrub species in Haloxylon (Amaranthaceae)

Cold-induced FOXO1 nuclear transport aids cold survival and tissue storage

DNMT1 modulation of RASSF1A methylation enhances breast cancer brain metastasis

Knockdown of EGFR inhibits growth and invasion of gastric cancer cells

Generation of whole tumor cell vaccine for on-demand manipulation of immune responses against cancer under near-infrared laser irradiation

Upregulation of MiR-205 transcriptionally suppresses SMAD4 and PTEN and contributes to human ovarian cancer progression

Multiplexed discrimination of SARS-CoV-2 variants via plasmonic-enhanced fluorescence in a portable and automated device

Role of GPX3+ astrocytes in breast cancer brain metastasis activated by circulating tumor cell exosomes

Mangrove reforestation provides greater blue carbon benefit than afforestation for mitigating global climate change

Introgressing the Aegilops tauschii genome into wheat as a basis for cereal improvement

Exosomes secreted from cardiomyocytes suppress the sensitivity of tumor ferroptosis in ischemic heart failure

Histamine H3 receptors aggravate cerebral ischaemic injury by histamine-independent mechanisms

FGF1^ΔHBS prevents diabetic cardiomyopathy by maintaining mitochondrial homeostasis and reducing oxidative stress via AMPK/Nur77 suppression

A multi-paradigm EEG dataset for studying upper limb rehabilitation exercises

ZBTB16 inhibits DNA replication and induces cell cycle arrest by targeting WDHD1 transcription in lung adenocarcinoma

Evaluation of a micro/nanofluidic chip platform for diagnosis of central nervous system infections: a multi-center prospective study

Kawasaki disease: ubiquitin-specific protease 5 promotes endothelial inflammation via TNFα-mediated signaling

Influence of aridity and salinity on plant nutrients scales up from species to community level in a desert ecosystem

Neutrophil heterogeneity in Kawasaki disease and multisystem inflammatory syndrome in children

Vitamin D sensitizes cervical cancer to radiation-induced apoptosis by inhibiting autophagy through degradation of Ambra1

Study on the fastening characteristics of preformed helical fittings considering the surface effect of transmission lines

Indoleamine 2,3-dioxygenase 1 limits hepatic inflammatory cells recruitment and promotes bile duct ligation-induced liver fibrosis

Impact of groundwater depth and soil salinity on riparian plant diversity and distribution in an arid area of China

Risk-prediction models for intravenous immunoglobulin resistance in Kawasaki disease: Risk-of-Bias Assessment using PROBAST

Search

Quick links

Search

Filter By:

Search

Quick links