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Showing 1–19 of 19 results

Advanced filters: Author: Guillermo Horga Clear advanced filters

The parieto-occipital cortex is a candidate neural substrate for the human ability to approximate Bayesian inference

Analysis of fMRI data from participants in a probability estimation task suggests that the parieto-occipital cortex is a neural substrate for humans’ ability to approximate Bayesian inference by integrating prior beliefs with new information.

Nicholas M. Singletary
Jacqueline Gottlieb
Guillermo Horga
ResearchOpen Access09 Feb 2024
Communications Biology

Volume: 7, P: 1-18
Neural Dysfunction in Cognitive Control Circuits in Persons at Clinical High-Risk for Psychosis

Tiziano Colibazzi
Guillermo Horga
Bradley S Peterson
Research10 Sept 2015
Neuropsychopharmacology

Volume: 41, P: 1241-1250
Refining mechanistic models of hallucinations for enhanced translatability

Justin Buck
Kiyohito Iigaya
Guillermo Horga
ReviewsOpen Access03 Dec 2025
Translational Psychiatry

Volume: 16, P: 1-10
Publisher Correction: An integrative framework for perceptual disturbances in psychosis

Guillermo Horga
Anissa Abi-Dargham
Amendments and Corrections10 Mar 2020
Nature Reviews Neuroscience

Volume: 21, P: 297
Retraction Note: Association between neuromelanin-sensitive MRI signal and psychomotor slowing in late-life depression

Kenneth Wengler
Brandon K. Ashinoff
Bret R. Rutherford
Amendments and Corrections28 Mar 2024
Neuropsychopharmacology

Volume: 49, P: 1202
Associations of neuromelanin in the substantia nigra with antipsychotic response in schizophrenia

Ryosuke Tarumi
Shiori Honda
Shinichiro Nakajima
Research07 Nov 2025
Neuropsychopharmacology

Volume: 51, P: 682-690
An integrative framework for perceptual disturbances in psychosis

Emerging data suggest a key role for dopamine in the perceptual disturbances that occur in psychotic disorders. In this Review, Horga and Abi-Dargham discuss a framework focused on perceptual inference, emphasizing the role of dopamine and the relevant associative cortico–striatal circuits.

Guillermo Horga
Anissa Abi-Dargham
Reviews11 Nov 2019
Nature Reviews Neuroscience

Volume: 20, P: 763-778
Widespread temporal coding of cognitive control in the human prefrontal cortex

Using intracranial recordings in humans, the authors found decision conflict-related effects on firing rate in the dorsal anterior cingulate cortex (dACC), on spike-phase coupling in the dACC, and on spike-field coherence in the dorsolateral prefrontal cortex.

Elliot H. Smith
Guillermo Horga
Sameer A. Sheth
Research30 Sept 2019
Nature Neuroscience

Volume: 22, P: 1883-1891
Neuromelanin-sensitive MRI for mechanistic research and biomarker development in psychiatry

Kenneth Wengler
Paula Trujillo
Guillermo Horga
Reviews19 Aug 2024
Neuropsychopharmacology

Volume: 50, P: 137-152
A neural code supporting prospective probabilistic reasoning for instrumental information demand in humans

Functional neuroimaging reveals multidimensional encodings of expected posterior certainty, possibly supporting humans’ ability to anticipate the value of gathering information before making a choice.

Nicholas M. Singletary
Guillermo Horga
Jacqueline Gottlieb
ResearchOpen Access02 Oct 2024
Communications Biology

Volume: 7, P: 1-15
The search for imaging biomarkers in psychiatric disorders

Abi-Dargham and Horga discuss the challenges of developing and standardizing brain-imaging technologies to aid with the diagnosis and treatment of psychiatric disorders.

Anissa Abi-Dargham
Guillermo Horga
Reviews26 Oct 2016
Nature Medicine

Volume: 22, P: 1248-1255
Replication of a neuroimaging biomarker for striatal dysfunction in psychosis

Jose M. Rubio
Todd Lencz
Anil K. Malhotra
Research04 Jan 2024
Molecular Psychiatry

Volume: 29, P: 929-938
RETRACTED ARTICLE: Association between neuromelanin-sensitive MRI signal and psychomotor slowing in late-life depression

Kenneth Wengler
Brandon K. Ashinoff
Bret R. Rutherford
Research12 Sept 2020
Neuropsychopharmacology

Volume: 46, P: 1233-1239
Introspective inference counteracts perceptual distortion

People can have perceptual illusions that they realize are not real. Here, the authors show that this type of reality testing can be explained by a Bayesian inference model that incorporates introspective knowledge.

Andra Mihali
Marianne Broeker
Guillermo Horga
ResearchOpen Access29 Nov 2023
Nature Communications

Volume: 14, P: 1-24
Kappa opioid receptor availability predicts severity of anhedonia in schizophrenia

Mark Slifstein
Wenchao Qu
Anissa Abi-Dargham
Research31 Aug 2024
Neuropsychopharmacology

Volume: 49, P: 2087-2093
Probing midbrain dopamine function in pediatric obsessive-compulsive disorder via neuromelanin-sensitive magnetic resonance imaging

David Pagliaccio
Kenneth Wengler
Rachel Marsh
Research17 May 2023
Molecular Psychiatry

Volume: 28, P: 3075-3082
Neuromelanin detection by magnetic resonance imaging (MRI) and its promise as a biomarker for Parkinson’s disease

David Sulzer
Clifford Cassidy
Luigi Zecca
ReviewsOpen Access10 Apr 2018
npj Parkinson's Disease

Volume: 4, P: 1-13
Proof of mechanism and target engagement of glutamatergic drugs for the treatment of schizophrenia: RCTs of pomaglumetad and TS-134 on ketamine-induced psychotic symptoms and pharmacoBOLD in healthy volunteers

Joshua T. Kantrowitz
Jack Grinband
Jeffrey A. Lieberman
ResearchOpen Access13 May 2020
Neuropsychopharmacology

Volume: 45, P: 1842-1850
Influences of dopaminergic system dysfunction on late-life depression

Warren D. Taylor
David H. Zald
Bret R. Rutherford
Reviews17 Aug 2021
Molecular Psychiatry

Volume: 27, P: 180-191