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The authors found esterified pectin localized at the stiff poles of maize stomata, modulating stomatal opening. These results reveal novel targets for stomatal engineering and breeding crops with higher water use efficiency.

The reactive nitrogen (Nr)-driven atmospheric multiphase buffering can induce unintended Concomitant Pollution. Given the importance of NH₃ in this process, rising global NH₃ emissions has positioned Concomitant Pollution as an urgent challenge.

Li et al. demonstrate mitochondrial fission in macrophages as key for phagocytosis induced by therapeutic antibodies. They identify overexpression of GFPT2 as an inhibitor of the process and phase transition of the phagocytic machinery as its regulator.

The benchmark fullerene-based electron-transporting materials (ETMs) for inverted perovskite solar cells are often limited by thermal evaporation or stability issues. Here the authors report solution-processable non-fullerene ETMs with improved device stability and efficiency.

Drought and cold in northern China during the 2.8 ka cold event contributed to the collapse of the Western Zhou Dynasty and subsequent significant southward migration, according to analyses of stalagmite records from Northeast and Southeast China.

The growth of monolayer hexagonal boron nitride (hBN) on insulating substrates could promote high-end applications of 2D (opto-)electronic devices, but remains difficult to achieve. Here, the authors report a stamp-like growth-transfer technique to produce inch-sized single-crystal hBN and graphene monolayers on various insulating substrates.

The role of type I interferons in bacterial infection is less clear than it is in viral infection. Here, the authors show that genetic variation of the human IFNAR1 gene is associated with decreased susceptibility to tuberculosis and identify a role for the IFNAR1 inter-domain region in the cytokine response.

Bacterial allosteric transcription factors can sense and respond to a variety of small molecules. Here the authors present CaT-SMelor which uses Cas12a and allosteric transcription factors to detect small molecules in the nanomolar range.

The oxidation of sulfur dioxide to sulfate by hydrogen peroxide in aerosol water significantly impacts global continental regions. Abating oxidants can facilitate the benefit of sulfur dioxide reduction and positive feedback in sulfate mitigation.

Materials with higher-order multistates are desired for non-Boolean high-density storage. Here the authors realized sextuple intrinsic polarization states in vdW CuInP₂S₆, and reversible transformation among sextuple-, quadruple-, and double-polarization orders.

The SARS-CoV-2 papain-like protease (PLpro) is of interest as a drug target. Here, the authors identify GRL0617 as a PPI (protein–protein interaction) inhibitor of SARS-CoV-2 PLpro that inhibits its deISGylating activity and present the mechanism of action of the compound through the GRL0617-bound PLpro crystal structure and NMR studies.

Utilizing the immense osmotic energy in membrane separation processes enables spontaneous lithium extraction while generating net energy, offering a promising method for carbon-negative resource recovery.

High mass loading and fast charge transport are two crucial but often mutually exclusive characteristics of pseudocapacitors. Here, the authors address this challenge by making use of block copolymer phase separation in the synthesis of porous carbon fibres as carbon supports for pseudocapacitors.

Colonoscopy is the most commonly used tool to screen for colorectal cancer (CRC). Here, the authors develop a deep learning model to perform optical diagnosis of CRC by training on a large data set of white-light colonoscopy images and achieve endoscopist-level performance on three independent datasets.

Listeria monocytogenes isolates are highly heterogeneous and exhibit different levels of virulence. Here, the authors identify hypervirulent isolates that represent a hybrid sub-lineage of the major lineage II harbouring virulence factors from Listeria ivanovii and wall teichoic acids found in major lineage I.

The ELI-TriScope advances cryo-CLEM by focusing light, electron and ion beams on cryopreserved samples for markedly improved preparation of cryo-lamellae containing target structures.

The bound loci and functions of chromatin-associated RNAs remain unclear in rice. This study develops an RNA–DNA mapping method to reveal the identity and interaction patterns around active promoters within hierarchical genome architecture.

How structural features on oocytes regulate mammalian female reproduction is unclear. Here, the authors provide imaging and physiological evidence (for example on Radixin knockout) to identify oocyte-derived mushroom-like microvilli that control the female reproductive lifespan by governing the fate of follicles.

The stereoselective synthesis of polyesters has been achieved via various methods; however, all routes show limited side-chain group functionality. Here the authors synthesize stereoblock polyesters by photoredox ring-opening polymerization of racemic O-carboxyanhydrides that have abundant side-chain functionality.

The codling moth, Cydia pomonella, is one of the major pests of pome fruit (apples and pears) and walnuts. Here, the authors sequence and analyze its genome, providing insights on olfactory and detoxification processes that may underlie its worldwide expansion.

T-acute lymphoblastic leukemia is an aggressive cancer. Here the authors provide insights into the functional role of SHQ1, an H/ACA snoRNP assembly factor involved in snRNA pseudouridylation, in T-lymphoblastic leukemia cell survival through regulating the maturation of MYC mRNA.

While photoelectrochemical devices combine light-absorption with fuel and electricity generation, their implementation is hampered by high costs and low output. Here, the authors synthesized acetylene-rich carbon fibers by copper-mediated polymerization for high-activity, metal-free photocathodes.

Xiaowen Sun and colleagues report the whole-genome sequencing of the common carp, Cyprinus carpio. They also resequenced 33 representative accessions from a worldwide collection and provide insights into population structure and evolution.

A dual-coupling-guided growth mechanism enables the realization of wafer-scale single-crystal WS₂ on vicinal a-plane sapphire.

Isoprene, temperature, and nitrogen oxides are the key drivers of ozone formation in Tianjin, China, according to a machine learning coupled structure mining method that could help inform local ozone pollution mitigation.

Existing healing experiments on self-healing bulk materials typically rely on manual contact of fracture interfaces. Development of 3D-architected lattice structures that can autonomously heal fractures or damages is still an outstanding engineering challenge. This paper presents a class of additively manufactured lattice structures that can autonomously heal fractures by first aligning fracture interfaces through a shape-memory process and then repairing fracture interfaces through a fracture-healing process. Through harnessing the coupling of shape-memory and self-healing, this paper also demonstrates reversible configuration transformations of lattice structures among states of different stiffnesses, vibration transmittances, and acoustic absorptions.