Nature Search

Alterations of HLA class I and class II antigen expressions in borderline, invasive and metastatic ovarian cancers

Youn Soo Lee
Tae Eung Kim
Jin Woo Kim
ResearchOpen Access01 Mar 2002
Experimental & Molecular Medicine

Volume: 34, P: 18-26
A SARS-CoV-2 M^pro mutation conferring ensitrelvir resistance paradoxically increases nirmatrelvir susceptibility

SARS-CoV-2 variants resistant to current antivirals pose a significant threat, especially to high-risk patients. The authors identify a deletion mutation in M^pro that confers resistance to ensitrelvir but increases susceptibility to nirmatrelvir, suggesting potential for sequential or alternative therapeutic strategies in prolonged antiviral treatments.

Seong Cheol Min
Jin-Ju Seo
Min-Suk Song
ResearchOpen Access22 Nov 2025
Nature Communications

Volume: 16, P: 1-15
Differential effects of lithium on metabolic dysfunctions in astrocytes derived from bipolar disorder patients

Gyu Hyeon Baek
Dayeon Kim
Jinju Han
ResearchOpen Access22 Aug 2025
Molecular Psychiatry

Volume: 30, P: 5833-5848
O-GlcNAc modification of leucyl-tRNA synthetase 1 integrates leucine and glucose availability to regulate mTORC1 and the metabolic fate of leucine

Leucyl-tRNA synthetase 1 (LARS1) is a leucine sensor for mTORC1 signaling and regulates leucine utilization depending on glucose availability. Here, the author show that O-GlcNAcylation of LARS1 is crucial for its ability to regulate mTORC1 activity and leucine metabolism upon glucose starvation.

Kibum Kim
Hee Chan Yoo
Jung Min Han
ResearchOpen Access25 May 2022
Nature Communications

Volume: 13, P: 1-19
Characterising acute and chronic care needs: insights from the Global Burden of Disease Study 2019

Chronic care manages long-term, progressive conditions, while acute care handles short-term ones. Here, authors show chronic conditions account for most of the global health burden, with 68% of DALYs and 93% of YLDs attributed to chronic care needs.

Cecilia Anza-Ramirez
J. Jaime Miranda
Yves Miel H. Zuniga
ResearchOpen Access07 May 2025
Nature Communications

Volume: 16, P: 1-36
CD99 type II is a determining factor for the differentiation of primitive neuroectodermal cells

Eun Jung Lee
Hyun Gyu Lee
Seong Hoe Park
ResearchOpen Access01 Oct 2003
Experimental & Molecular Medicine

Volume: 35, P: 438-447
Phospholipase C isozymes selectively couple to specific neurotransmitter receptors

Daesoo Kim
Ki Sun Jun
Hee-Sup Shin
Research18 Sept 1997
Nature

Volume: 389, P: 290-293
AIMP2-DX2 provides therapeutic interface to control KRAS-driven tumorigenesis

Direct targeting of oncogenic KRAS activity is a challenge. Here the authors report that a splice variant of AIMP2, AIMP2-DX2, enhances KRAS stability by blocking ubiquitin-mediated degradation of KRAS via the E3 ligase, Smurf2, and identify a chemical that can hinder AIMP2-DX2 from interacting with KRAS.

Dae Gyu Kim
Yongseok Choi
Sunghoon Kim
ResearchOpen Access11 May 2022
Nature Communications

Volume: 13, P: 1-17
Engineering N-glycosylation mutations in IL-12 enhances sustained cytotoxic T lymphocyte responses for DNA immunization

Sang J. Ha
Jun Chang
Young C. Sung
Research01 Apr 2002
Nature Biotechnology

Volume: 20, P: 381-386
Discovery and genomic characterization of Ulleung virus harbored by Crocidura utsuryoensis on Ulleung Island in Republic of Korea

Kyungmin Park
Jaeyeon Lee
Jin-Won Song
ResearchOpen Access01 Jul 2025
Scientific Reports

Volume: 15, P: 1-11
Vibrio sp. dhg as a platform for the biorefinery of brown macroalgae

Brown macroalgae is a good candidate feedstock for biorefinery, but the major carbohydrate alginate cannot be digested by current industrial microbes. Here, the authors isolate Vibrio sp. dhg and engineer it to produce value-added biochemicals from alginate using newly developed genetic tools.

Hyun Gyu Lim
Dong Hun Kwak
Gyoo Yeol Jung
ResearchOpen Access06 Jun 2019
Nature Communications

Volume: 10, P: 1-9
Asymmetric optical camouflage: tuneable reflective colour accompanied by the optical Janus effect

Taehyun Kim
Eui-Sang Yu
Yong-Sang Ryu
ResearchOpen Access19 Oct 2020
Light: Science & Applications

Volume: 9, P: 1-10
Author Correction: A cross-sectional study of ophthalmologic examination findings in 5385 Koreans presenting with intermittent exotropia

Dae Hee Kim
Jae Ho Jung
Soon Young Cho
Amendments and CorrectionsOpen Access14 Feb 2023
Scientific Reports

Volume: 13, P: 1
Healthcare utilization among children and young people with life-limiting conditions: Exploring palliative care needs using National Health Insurance claims data

Cho Hee Kim
In Gyu Song
Hee Young Shin
ResearchOpen Access14 Feb 2020
Scientific Reports

Volume: 10, P: 1-10
Targeting the interaction of AIMP2-DX2 with HSP70 suppresses cancer development

The cellular stability of an oncogenic factor, AIMP2-DX2, is increased via association with HSP70. Interference with this interaction by a small-molecule compound promotes ubiquitin-mediated degradation of AIMP2-DX2 and reduces cancer cell growth.

Semi Lim
Hye Young Cho
Sunghoon Kim
Research02 Dec 2019
Nature Chemical Biology

Volume: 16, P: 31-41
Electrochemically initiated synthesis of ethylene carbonate from CO₂

Electrochemical methods have great potential to help achieve net-zero emissions. Here, a method to synthesize ethylene carbonate is reported, which is electrochemically initiated and enables the concurrent production of hydrogen, capture of CO₂ and subsequent conversion of the captured CO₂ during ethylene carbonate synthesis.

Jun Ho Jang
Changsoo Kim
Ki Tae Nam
Research23 May 2024
Nature Synthesis

Volume: 3, P: 846-857
A cross-sectional study of ophthalmologic examination findings in 5385 Koreans presenting with intermittent exotropia

Dae Hee Kim
Jae Ho Jung
Soon Young Cho
ResearchOpen Access24 Jan 2023
Scientific Reports

Volume: 13, P: 1-8
The self-activated radical doping effects on the catalyzed surface of amorphous metal oxide films

Hong Jae Kim
Young Jun Tak
Hyun Jae Kim
ResearchOpen Access29 Sept 2017
Scientific Reports

Volume: 7, P: 1-9
Genome-wide expression profiling of 8-chloroadenosine- and 8-chloro-cAMP-treated human neuroblastoma cells using radioactive human cDNA microarray

Gil Hong Park
Jaegol Choe
Meyoung-Kon Kim
ResearchOpen Access01 Jul 2002
Experimental & Molecular Medicine

Volume: 34, P: 184-193
Molecular evolution and reassortment dynamics of Orthohantavirus hantanense revealed through longitudinal genomic surveillance in the Republic of Korea

Kyungmin Park
Jongwoo Kim
Jin-Won Song
ResearchOpen Access09 Jul 2025
Scientific Reports

Volume: 15, P: 1-11
Bioinformatic analysis of peripheral blood RNA-sequencing sensitively detects the cause of late graft loss following overt hyperglycemia in pig-to-nonhuman primate islet xenotransplantation

Hyun-Je Kim
Ji Hwan Moon
Chung-Gyu Park
ResearchOpen Access11 Dec 2019
Scientific Reports

Volume: 9, P: 1-11
Inactivation of farnesyltransferase and geranylgeranyltransferase I by caspase-3: Cleavage of the common α subunit during apoptosis

Ki-Woo Kim
Hyun-Ho Chung
Yong-Keun Jung
Research12 Mar 2001
Oncogene

Volume: 20, P: 358-366
Author Correction: Healthcare utilization among children and young people with life-limiting conditions: Exploring palliative care needs using National Health Insurance claims data

Cho Hee Kim
In Gyu Song
Hee Young Shin
Amendments and CorrectionsOpen Access11 Aug 2020
Scientific Reports

Volume: 10, P: 1-3
Recombinant adenoviruses expressing dominant negative insulin-like growth factor-I receptor demonstrate antitumor effects on lung cancer

Choon-Taek Lee
Kyung-Ho Park
David P Carbone
Research18 Dec 2002
Cancer Gene Therapy

Volume: 10, P: 57-63
Gestational diabetes mellitus and the role of intercurrent type 2 diabetes on long-term risk of cardiovascular events

Jiyu Sun
Gyu Ri Kim
Hyeon Chang Kim
ResearchOpen Access27 Oct 2021
Scientific Reports

Volume: 11, P: 1-9
Impact of organic liquid fertilizer on plant growth of Chinese cabbage and soil bacterial communities

Junkyung Lee
Na-Yeon Jo
Sun-Goo Hwang
ResearchOpen Access26 Mar 2025
Scientific Reports

Volume: 15, P: 1-12
Pathway optimization by re-design of untranslated regions for L-tyrosine production in Escherichia coli

Seong Cheol Kim
Byung Eun Min
Gyoo Yeol Jung
ResearchOpen Access08 Sept 2015
Scientific Reports

Volume: 5, P: 1-8
Cell-surface major vault protein promotes cancer progression through harboring mesenchymal and intermediate circulating tumor cells in hepatocellular carcinomas

Hyun Min Lee
Jae Won Joh
Chun Jeih Ryu
ResearchOpen Access16 Oct 2017
Scientific Reports

Volume: 7, P: 1-15
ANO9/TMEM16J promotes tumourigenesis via EGFR and is a novel therapeutic target for pancreatic cancer

Ikhyun Jun
Hyung Soon Park
Min Goo Lee
ResearchOpen Access12 Oct 2017
British Journal of Cancer

Volume: 117, P: 1798-1809
Sirt6 cooperates with Blimp1 to positively regulate osteoclast differentiation

So Jeong Park
Jeong-Eun Huh
Soo Young Lee
ResearchOpen Access18 May 2016
Scientific Reports

Volume: 6, P: 1-10
An effective peptide vaccine strategy circumventing clonal MHC heterogeneity of murine myeloid leukaemia

A-Ri Shin
Sang-Eun Lee
Tai-Gyu Kim
ResearchOpen Access29 Jun 2020
British Journal of Cancer

Volume: 123, P: 919-931
Uric acid level and kidney function: a cross-sectional study of the Korean national health and nutrition examination survey (2016–2017)

Hye Jin Joo
Gyu Ri Kim
Eun-Cheol Park
ResearchOpen Access10 Dec 2020
Scientific Reports

Volume: 10, P: 1-11
Synergistic association of high-sensitivity C-reactive protein and body mass index with insulin resistance in non-diabetic adults

Gyu Ri Kim
Dong-Woo Choi
Eun-Cheol Park
ResearchOpen Access28 Oct 2020
Scientific Reports

Volume: 10, P: 1-8
Integrin α6β4-Src-AKT signaling induces cellular senescence by counteracting apoptosis in irradiated tumor cells and tissues

Seung Hee Jung
Minyoung Lee
Jae-Seon Lee
Research21 May 2018
Cell Death & Differentiation

Volume: 26, P: 245-259
The effect of pupil transmittance on axial resolution of reflection phase microscopy

Min Gyu Hyeon
Kwanjun Park
Youngwoon Choi
ResearchOpen Access23 Nov 2021
Scientific Reports

Volume: 11, P: 1-9
A novel Epstein–Barr virus-latent membrane protein-1-specific T-cell receptor for TCR gene therapy

Hyun-Il Cho
Un-Hee Kim
Tai-Gyu Kim
ResearchOpen Access23 Jan 2018
British Journal of Cancer

Volume: 118, P: 534-545

Search

Alterations of HLA class I and class II antigen expressions in borderline, invasive and metastatic ovarian cancers

A SARS-CoV-2 M^pro mutation conferring ensitrelvir resistance paradoxically increases nirmatrelvir susceptibility

Differential effects of lithium on metabolic dysfunctions in astrocytes derived from bipolar disorder patients

O-GlcNAc modification of leucyl-tRNA synthetase 1 integrates leucine and glucose availability to regulate mTORC1 and the metabolic fate of leucine

Characterising acute and chronic care needs: insights from the Global Burden of Disease Study 2019

CD99 type II is a determining factor for the differentiation of primitive neuroectodermal cells

Phospholipase C isozymes selectively couple to specific neurotransmitter receptors

AIMP2-DX2 provides therapeutic interface to control KRAS-driven tumorigenesis

Engineering N-glycosylation mutations in IL-12 enhances sustained cytotoxic T lymphocyte responses for DNA immunization

Discovery and genomic characterization of Ulleung virus harbored by Crocidura utsuryoensis on Ulleung Island in Republic of Korea

Vibrio sp. dhg as a platform for the biorefinery of brown macroalgae

Asymmetric optical camouflage: tuneable reflective colour accompanied by the optical Janus effect

Author Correction: A cross-sectional study of ophthalmologic examination findings in 5385 Koreans presenting with intermittent exotropia

Healthcare utilization among children and young people with life-limiting conditions: Exploring palliative care needs using National Health Insurance claims data

Targeting the interaction of AIMP2-DX2 with HSP70 suppresses cancer development

Electrochemically initiated synthesis of ethylene carbonate from CO₂

A cross-sectional study of ophthalmologic examination findings in 5385 Koreans presenting with intermittent exotropia

The self-activated radical doping effects on the catalyzed surface of amorphous metal oxide films

Genome-wide expression profiling of 8-chloroadenosine- and 8-chloro-cAMP-treated human neuroblastoma cells using radioactive human cDNA microarray

Molecular evolution and reassortment dynamics of Orthohantavirus hantanense revealed through longitudinal genomic surveillance in the Republic of Korea

Bioinformatic analysis of peripheral blood RNA-sequencing sensitively detects the cause of late graft loss following overt hyperglycemia in pig-to-nonhuman primate islet xenotransplantation

Inactivation of farnesyltransferase and geranylgeranyltransferase I by caspase-3: Cleavage of the common α subunit during apoptosis

Author Correction: Healthcare utilization among children and young people with life-limiting conditions: Exploring palliative care needs using National Health Insurance claims data

Recombinant adenoviruses expressing dominant negative insulin-like growth factor-I receptor demonstrate antitumor effects on lung cancer

Gestational diabetes mellitus and the role of intercurrent type 2 diabetes on long-term risk of cardiovascular events

Impact of organic liquid fertilizer on plant growth of Chinese cabbage and soil bacterial communities

Pathway optimization by re-design of untranslated regions for L-tyrosine production in Escherichia coli

Cell-surface major vault protein promotes cancer progression through harboring mesenchymal and intermediate circulating tumor cells in hepatocellular carcinomas

ANO9/TMEM16J promotes tumourigenesis via EGFR and is a novel therapeutic target for pancreatic cancer

Sirt6 cooperates with Blimp1 to positively regulate osteoclast differentiation

An effective peptide vaccine strategy circumventing clonal MHC heterogeneity of murine myeloid leukaemia

Uric acid level and kidney function: a cross-sectional study of the Korean national health and nutrition examination survey (2016–2017)

Synergistic association of high-sensitivity C-reactive protein and body mass index with insulin resistance in non-diabetic adults

Integrin α6β4-Src-AKT signaling induces cellular senescence by counteracting apoptosis in irradiated tumor cells and tissues

The effect of pupil transmittance on axial resolution of reflection phase microscopy

A novel Epstein–Barr virus-latent membrane protein-1-specific T-cell receptor for TCR gene therapy

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