Nature Search

Angle-resolved phase-sensitive determination of the in-plane gap symmetry in YBa₂Cu₃O_7−δ

J. R. Kirtley
C. C. Tsuei
H. Hilgenkamp
Research05 Feb 2006
Nature Physics

Volume: 2, P: 190-194
Pure $d_{x^{2} - y^{2}}$ order-parameter symmetry in the tetragonal superconductor TI₂Ba₂CuO_6+δ

C. C. Tsuei
J. R. Kirtley
Z. Z. Li
Research29 May 1997
Nature

Volume: 387, P: 481-483
A novel coenzyme from bacterial primary alcohol dehydrogenases

S. A. SALISBURY
H. S. FORREST
O. KENNARD
Research30 Aug 1979
Nature

Volume: 280, P: 843-844
Pathogenic UNC13A variants cause a neurodevelopmental syndrome by impairing synaptic function

Pathogenic variants in UNC13A underlie a novel neurodevelopmental syndrome, with three subtypes defined by distinct genotypes with varying clinical and functional impacts characterized in cellular and animal models.

Reza Asadollahi
Aisha Ahmad
Noa Lipstein
ResearchOpen Access22 Oct 2025
Nature Genetics

Volume: 57, P: 2691-2704
Time-reversal symmetry-breaking superconductivity in Sr₂RuO₄

G. M. Luke
Y. Fudamoto
M. Sigrist
Research06 Aug 1998
Nature

Volume: 394, P: 558-561
Autophagy within the mushroom body protects from synapse aging in a non-cell autonomous manner

The role of macroautophagy in neuronal processes mediating brain maintenance remains enigmatic. Authors show here that impairing autophagy within the major learning related brain center of Drosophila, and not other regions, triggered a form of presynaptic metaplasticity that was invariably connected to the absence of the specific component of aversive olfactory memory, which normally only declines in the course of aging process

Anuradha Bhukel
Christine Brigitte Beuschel
Stephan J. Sigrist
ResearchOpen Access21 Mar 2019
Nature Communications

Volume: 10, P: 1-13
Spermidine is essential for fasting-mediated autophagy and longevity

Hofer et al. show that fasting promotes the synthesis of spermidine, which stimulates eIF5A hypusination to induce autophagy and increase lifespan in various species in a conserved manner.

Sebastian J. Hofer
Ioanna Daskalaki
Frank Madeo
ResearchOpen Access08 Aug 2024
Nature Cell Biology

Volume: 26, P: 1571-1584
Active zone scaffolds differentially accumulate Unc13 isoforms to tune Ca²⁺ channel–vesicle coupling

Coupling distances between synaptic vesicles and Ca²⁺ channels determine the efficacy of neurotransmission. Böhme et al. find that presynaptic scaffold complexes spatiotemporally control Unc13 isoforms to establish two independent release pathways at subsynaptic active zones: Unc13B defines nascent, loosely coupled synapses whereas Unc13A facilitates release at mature synapses by tight coupling between Ca²⁺ channels and synaptic vesicles.

Mathias A Böhme
Christina Beis
Stephan J Sigrist
Research15 Aug 2016
Nature Neuroscience

Volume: 19, P: 1311-1320
Presynaptic spinophilin tunes neurexin signalling to control active zone architecture and function

Synaptic assembly depends on trans-synaptic Neurexin/Neuroligin signalling. Here, Muhammad et al. show that Spinophilin, a pre-synaptic scaffolding protein, interacts with Neurexin, in competition with Syd-1, to regulate the formation and function of synaptic active zones at Drosophilaneuromuscular junctions.

Karzan Muhammad
Suneel Reddy-Alla
Stephan J. Sigrist
ResearchOpen Access16 Oct 2015
Nature Communications

Volume: 6, P: 1-15
Molecular genetic divergence analysis amongst high curcumin lines of Golden Crop (Curcuma longa L.) using SSR marker and use in trait-specific breeding

Anindita Gogoi
Sunita Munda
Mohan Lal
ResearchOpen Access11 Nov 2023
Scientific Reports

Volume: 13, P: 1-18
The flavonoid 4,4′-dimethoxychalcone promotes autophagy-dependent longevity across species

Although ageing is the most important risk factor for chronic ailments, effective interventions remain rare. Here, the authors identify the flavonoid 4,4’-dimethoxychalcone and demonstrate that it extends lifespan and promotes health in multiple organisms by inducing autophagy.

Didac Carmona-Gutierrez
Andreas Zimmermann
Frank Madeo
ResearchOpen Access19 Feb 2019
Nature Communications

Volume: 10, P: 1-17
Morphological flexibility in robotic systems through physical polygon meshing

Robots that can change their shape offer flexible functionality. A modular robotic platform is shown that implements physical polygon meshing, by combining triangles with sides of adjustable lengths, allowing flexible three-dimensional shape configurations.

Christoph H. Belke
Kevin Holdcroft
Jamie Paik
Research12 Jun 2023
Nature Machine Intelligence

Volume: 5, P: 669-675
The trispecific DARPin ensovibep inhibits diverse SARS-CoV-2 variants

Multiple variants of SARS-CoV-2 are inhibited by a trispecific DARPin.

Sylvia Rothenberger
Daniel L. Hurdiss
Jakob Trimpert
ResearchOpen Access21 Jul 2022
Nature Biotechnology

Volume: 40, P: 1845-1854
Liprin-α proteins are master regulators of human presynapse assembly

This paper identifies the evolutionarily conserved liprin-α protein family as key mediators of presynaptic assembly in human neurons. Their recruitment to sites formed by contacting neurons is the critical initial step that triggers presynaptic differentiation.

Berta Marcó de la Cruz
Joaquín Campos
Fredrik H. Sterky
ResearchOpen Access12 Mar 2024
Nature Neuroscience

Volume: 27, P: 629-642
Cardioprotection and lifespan extension by the natural polyamine spermidine

Spermidine, a naturally occurring polyamine, extends the lifespan of mice and is cardioprotective in both aged mice and hypertensive rats. In humans, high dietary spermidine intake is associated with reduced blood pressure and a lower incidence of cardiovascular disease.

Tobias Eisenberg
Mahmoud Abdellatif
Frank Madeo
Research14 Nov 2016
Nature Medicine

Volume: 22, P: 1428-1438
PKC-phosphorylation of Liprin-α3 triggers phase separation and controls presynaptic active zone structure

Liquid–liquid phase separation may be a mechanism for organizing the presynaptic nerve terminal. Here, the authors show that PKC-mediated phosphorylation of Liprin-α3 triggers phase separation in cell lines and modulates active zone structure and function in primary hippocampal neurons.

Javier Emperador-Melero
Man Yan Wong
Pascal S. Kaeser
ResearchOpen Access24 May 2021
Nature Communications

Volume: 12, P: 1-17
Interactions of branched-chain amino acids in mouse brain cell cultures

H P Schwarz
V Sigrist
T Schaefer
Research01 Aug 1984
Pediatric Research

Volume: 18, P: 804
The transcription factor cyclic AMP–responsive element–binding protein H regulates triglyceride metabolism

The transcription factor CREB-H has been found to regulate the expression of a suite of genes in mice that are involved in triglyceride metabolism, according to a new study by Ann-Hwee Lee and her colleagues. They also find loss-of-function mutations in the human gene for CREB-H that are associated with highly elevated levels of triglycerides, suggesting a similar role for the protein in humans.

Jung Hoon Lee
Petros Giannikopoulos
Ann-Hwee Lee
Research12 Jun 2011
Nature Medicine

Volume: 17, P: 812-815
Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1

Neal N. Iwakoshi
Ann-Hwee Lee
Laurie H. Glimcher
Research03 Mar 2003
Nature Immunology

Volume: 4, P: 321-329
LRRK2 regulates retrograde synaptic compensation at the Drosophila neuromuscular junction

Mutations in the protein LRRK2 have been associated with Parkinson's disease but little is still known about the basic functions of the protein in the brain. Here the authors show that in fruit flies, LRRK2 regulates retrograde homeostatic synaptic compensation at the larval neuromuscular junction.

Jay Penney
Kazuya Tsurudome
A. Pejmun Haghighi
ResearchOpen Access19 Jul 2016
Nature Communications

Volume: 7, P: 1-14
Bose–Einstein condensation of the triplet states in the magnetic insulator TlCuCl₃

Ch. Rüegg
N. Cavadini
P. Vorderwisch
Research01 May 2003
Nature

Volume: 423, P: 62-65
Plasma cell differentiation requires the transcription factor XBP-1

Andreas M. Reimold
Neal N. Iwakoshi
Laurie H. Glimcher
Research19 Jul 2001
Nature

Volume: 412, P: 300-307
Serine phosphorylation of ephrinB2 regulates trafficking of synaptic AMPA receptors

The shuttling of AMPA receptors to and from the synaptic membrane determines the strength of synaptic transmission. This study shows that ephrinB2 is part of the mechanism that stabilizes AMPA receptors at the synaptic surface. EphrinB2 and AMPA receptors are linked by two PDZ domains in the intracellular adaptor protein GRIP.

Clara L Essmann
Elsa Martinez
Amparo Acker-Palmer
Research10 Aug 2008
Nature Neuroscience

Volume: 11, P: 1035-1043
TRANSPLANTATION AND IN VITRO ANALYSIS OF SOYBEAN-AGGLUTININ SEPARATED MOUSE SPLEEN CELLS

W Mannhardt
J Düber
H Schulte-Wissermann
Research01 Aug 1984
Pediatric Research

Volume: 18, P: 804
Spin-triplet superconductivity in Sr₂RuO₄ identified by ¹⁷O Knight shift

K. Ishida
H. Mukuda
Y. Maeno
Research17 Dec 1998
Nature

Volume: 396, P: 658-660
Evidence of Andreev bound states as a hallmark of the FFLO phase in κ-(BEDT-TTF)₂Cu(NCS)₂

A Fulde–Ferrell–Larkin–Ovchinnikov superconductor comprises pairs of fermions with non-zero momentum, which form alternating superconducting and normal regions in a magnetic field. NMR measurements now provide microscopic evidence for such a state.

H. Mayaffre
S. Krämer
V. F. Mitrović
Research26 Oct 2014
Nature Physics

Volume: 10, P: 928-932
The E3 ubiquitin ligase Wwp2 regulates craniofacial development through mono-ubiquitylation of Goosecoid

Deletion of the E3 ubiquitin ligase Wwp2 in mice is shown to induce malformations in the craniofacial regions. Wwp2 mono-ubiquitylates Goosecoid, a modification found to be essential for Goosecoid effects on the transcription of the cartilage regulatory protein Sox6.

Weiguo Zou
Xi Chen
Dallas Jones
Research19 Dec 2010
Nature Cell Biology

Volume: 13, P: 59-65
In vivo genome editing using novel AAV-PHP variants rescues motor function deficits and extends survival in a SOD1-ALS mouse model

Yi A. Chen
Mark W. Kankel
Shih-Ching Lo
Research01 Dec 2022
Gene Therapy

Volume: 30, P: 443-454
23 INDICATIONS AND RESULTS OF BONE MARROW TRANSPLANTATION IN CHILDHOOD ACUTE LEUKEMIA (AL)

H J Plüss
J Sigrist
W H Hitzig
Research01 Aug 1979
Pediatric Research

Volume: 13, P: 952
MTSS1, a novel target of DNA methyltransferase 3B, functions as a tumor suppressor in hepatocellular carcinoma

H Fan
L Chen
X-Y Guan
Research12 Sept 2011
Oncogene

Volume: 31, P: 2298-2308
Contribution of Cystine–Glutamate Antiporters to the Psychotomimetic Effects of Phencyclidine

David A Baker
Aric Madayag
Ilangovan Raju
Research29 Aug 2007
Neuropsychopharmacology

Volume: 33, P: 1760-1772
173 COMPARISON OF FRUCTOSAMINE AND GLYCATED HAEMOGLOBIN IN CHILDREN WITH TYPE 1 DIABETES MELLITUS

P Mullis
H Völkle
K Zuppinger
Research01 Oct 1988
Pediatric Research

Volume: 24, P: 546
Climate change, tropical fisheries and prospects for sustainable development

Stressors arising from anthropogenic climate change threaten tropical fisheries and, in turn, those extratropical nations reliant on them. This Review discusses the impact of climate change on tropical fish stocks and catch potential, the corresponding telecoupling and subsequent adaptation measures.

Vicky W. Y. Lam
Edward H. Allison
U. Rashid Sumaila
Reviews04 Aug 2020
Nature Reviews Earth & Environment

Volume: 1, P: 440-454
Altered emotionality and neuronal excitability in mice lacking KCTD12, an auxiliary subunit of GABA_B receptors associated with mood disorders

F Cathomas
M Stegen
C R Pryce
ResearchOpen Access17 Feb 2015
Translational Psychiatry

Volume: 5, P: e510
AK2 deficiency compromises the mitochondrial energy metabolism required for differentiation of human neutrophil and lymphoid lineages

E Six
C Lagresle-Peyrou
M Cavazzana
ResearchOpen Access13 Aug 2015
Cell Death & Disease

Volume: 6, P: e1856

Search

Angle-resolved phase-sensitive determination of the in-plane gap symmetry in YBa₂Cu₃O_7−δ

Pure $d_{x^{2} - y^{2}}$ order-parameter symmetry in the tetragonal superconductor TI₂Ba₂CuO_6+δ

A novel coenzyme from bacterial primary alcohol dehydrogenases

Pathogenic UNC13A variants cause a neurodevelopmental syndrome by impairing synaptic function

Time-reversal symmetry-breaking superconductivity in Sr₂RuO₄

Autophagy within the mushroom body protects from synapse aging in a non-cell autonomous manner

Spermidine is essential for fasting-mediated autophagy and longevity

Active zone scaffolds differentially accumulate Unc13 isoforms to tune Ca²⁺ channel–vesicle coupling

Presynaptic spinophilin tunes neurexin signalling to control active zone architecture and function

Molecular genetic divergence analysis amongst high curcumin lines of Golden Crop (Curcuma longa L.) using SSR marker and use in trait-specific breeding

The flavonoid 4,4′-dimethoxychalcone promotes autophagy-dependent longevity across species

Morphological flexibility in robotic systems through physical polygon meshing

The trispecific DARPin ensovibep inhibits diverse SARS-CoV-2 variants

Liprin-α proteins are master regulators of human presynapse assembly

Cardioprotection and lifespan extension by the natural polyamine spermidine

PKC-phosphorylation of Liprin-α3 triggers phase separation and controls presynaptic active zone structure

Interactions of branched-chain amino acids in mouse brain cell cultures

The transcription factor cyclic AMP–responsive element–binding protein H regulates triglyceride metabolism

Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1

LRRK2 regulates retrograde synaptic compensation at the Drosophila neuromuscular junction

Bose–Einstein condensation of the triplet states in the magnetic insulator TlCuCl₃

Plasma cell differentiation requires the transcription factor XBP-1

Serine phosphorylation of ephrinB2 regulates trafficking of synaptic AMPA receptors

TRANSPLANTATION AND IN VITRO ANALYSIS OF SOYBEAN-AGGLUTININ SEPARATED MOUSE SPLEEN CELLS

Spin-triplet superconductivity in Sr₂RuO₄ identified by ¹⁷O Knight shift

Evidence of Andreev bound states as a hallmark of the FFLO phase in κ-(BEDT-TTF)₂Cu(NCS)₂

The E3 ubiquitin ligase Wwp2 regulates craniofacial development through mono-ubiquitylation of Goosecoid

In vivo genome editing using novel AAV-PHP variants rescues motor function deficits and extends survival in a SOD1-ALS mouse model

23 INDICATIONS AND RESULTS OF BONE MARROW TRANSPLANTATION IN CHILDHOOD ACUTE LEUKEMIA (AL)

MTSS1, a novel target of DNA methyltransferase 3B, functions as a tumor suppressor in hepatocellular carcinoma

Contribution of Cystine–Glutamate Antiporters to the Psychotomimetic Effects of Phencyclidine

173 COMPARISON OF FRUCTOSAMINE AND GLYCATED HAEMOGLOBIN IN CHILDREN WITH TYPE 1 DIABETES MELLITUS

Climate change, tropical fisheries and prospects for sustainable development

Altered emotionality and neuronal excitability in mice lacking KCTD12, an auxiliary subunit of GABA_B receptors associated with mood disorders

AK2 deficiency compromises the mitochondrial energy metabolism required for differentiation of human neutrophil and lymphoid lineages

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