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Advanced filters: Author: Hadas Biran Clear advanced filters

lncRNA NORAD modulates STAT3/STAT1 balance and innate immune responses in human cells via interaction with STAT3

Long non-coding RNA (lncRNA) has diverse functions. Here the authors show that a lncRNA, NORAD, interacts with an immune transcription factor, STAT3, to facilitate STAT3 nuclear import and thereby modulating the intranuclear balance between STAT3 and STAT1 and the downstream activation of anti-viral immunity in vitro.

Amir Argoetti
Dor Shalev
Yael Mandel-Gutfreund
ResearchOpen Access10 Jan 2025
Nature Communications

Volume: 16, P: 1-14
Detecting significant expression patterns in single-cell and spatial transcriptomics with a flexible computational approach

Hadas Biran
Tamar Hashimshony
Zohar Yakhini
ResearchOpen Access30 Oct 2024
Scientific Reports

Volume: 14, P: 1-21
Inferring single-cell and spatial microRNA activity from transcriptomics data

This study introduces miTEA-HiRes, a method designed to facilitate the evaluation of miRNA activity at high resolution. The method applies to single cell transcriptomics, type-specific single cell populations, and spatial transcriptomics data.

Efrat Herbst
Yael Mandel-Gutfreund
Hadas Biran
ResearchOpen Access18 Jan 2025
Communications Biology

Volume: 8, P: 1-18
New ARCHITECT plasma pro-gastrin-releasing peptide assay for diagnosing and monitoring small-cell lung cancer

Benjamin Nisman
Hovav Nechushtan
Tamar Peretz
ResearchOpen Access26 Jan 2016
British Journal of Cancer

Volume: 114, P: 469-476

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