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Showing 1–7 of 7 results
Advanced filters: Author: Hananeh Aliee Clear advanced filters

  • Glial cells and their crosstalk after injury are crucial for brain regeneration. Here, the authors show the spatial, temporal, and single-cell responses of glial cells after injury and identify shared pathways controlling glial reactivity.

    • Christina Koupourtidou
    • Veronika Schwarz
    • Jovica Ninkovic
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-22

  • Single-cell RNA sequencing and spatiotemporal analysis of the regenerating zebrafish heart identify transient proregenerative fibroblast-like cells that are derived from the epicardium and the endocardium. Wnt signalling regulates the endocardial fibroblast response.

    • Bo Hu
    • Sara Lelek
    • Jan Philipp Junker
    ResearchOpen Access
    Nature Genetics
    Volume: 54, P: 1227-1237

  • The molecular basis and gene regulatory networks driving pharyngeal endoderm development remain poorly understood. Here the authors report single cell transcriptomic and chromatin landscapes to delineate regulatory programs driving this process and to define the immunodeficiency-associated developmental defects resulting from Foxn1 dysfunction.

    • Margaret E. Magaletta
    • Macrina Lobo
    • René Maehr
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-16

  • An integrated analysis of over 100 single-cell and single-nucleus transcriptomics studies illustrates severe acute respiratory syndrome coronavirus 2 viral entry gene coexpression patterns across different human tissues, and shows association of age, smoking status and sex with viral entry gene expression in respiratory cell populations.

    • Christoph Muus
    • Malte D. Luecken
    • Xiaohui Zhang
    Research
    Nature Medicine
    Volume: 27, P: 546-559

  • This Perspective explores causal machine learning in single-cell genomics, addressing challenges such as generalization, interpretability and cell dynamics, while highlighting advances and the potential to uncover new insights into cellular mechanisms.

    • Alejandro Tejada-Lapuerta
    • Paul Bertin
    • Fabian J. Theis
    Reviews
    Nature Genetics
    Volume: 57, P: 797-808

  • Practitioners in the field of single-cell omics are now faced with diverse options for analytical tools to process and integrate data from various molecular modalities. In an Expert Recommendation article, the authors provide guidance on robust single-cell data analysis, including choices of best-performing tools from benchmarking studies.

    • Lukas Heumos
    • Anna C. Schaar
    • Fabian J. Theis
    Reviews
    Nature Reviews Genetics
    Volume: 24, P: 550-572