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Showing 1–12 of 12 results

Advanced filters: Author: Haonan Zhong Clear advanced filters

Nucleophosmin 1 lactylation in graft kidney induces ferroptotic trigger waves that exacerbate delayed graft function

Ferroptotic propagation aggravates kidney ischemia-reperfusion injury and causes delayed graft function. Here, the authors show that inhibiting lactate shuttle and AARS1-mediated NPM1 lactylation protects graft function by blocking ferroptotic waves.

Haitao Yu
Hubin Yin
Xinyuan Li
ResearchOpen Access05 Dec 2025
Nature Communications

Volume: 17, P: 1-20
Identification of splenic IRF7 as a nanotherapy target for tele-conditioning myocardial reperfusion injury

Treating myocardial reperfusion injury via nanotherapy is challenging due to clearance by the mononuclear phagocyte system. Here, the authors target the spleen to reduce acute heart injury and improve long-term cardiac function via transient IRF7 inhibition.

Qiang Long
Kristina Rabi
Xiaofeng Ye
ResearchOpen Access24 Feb 2025
Nature Communications

Volume: 16, P: 1-20
Structural basis for the evolution and antibody evasion of SARS-CoV-2 BA.2.86 and JN.1 subvariants

Here, the authors evaluate the neutralization susceptibilities of BA.2.86 and JN.1 and determine the structural basis for binding to the ACE2 receptor and monoclonal neutralizing antibodies, revealing their evolution and antibody evasion mechanism.

Haonan Yang
Huimin Guo
Zheng Zhang
ResearchOpen Access04 Sept 2024
Nature Communications

Volume: 15, P: 1-14
Long-term monitoring of ultratrace nucleic acids using tetrahedral nanostructure-based NgAgo on wearable microneedles

Monitoring of biomarkers with wearable devices holds potential for personal health management. Here the authors demonstrate a wearable device based on tetrahedral DNA nanostructures and prokaryotic argonaute to monitor real-time sepsis-associated nucleic acid

Bin Yang
Haonan Wang
Xueen Fang
ResearchOpen Access02 Mar 2024
Nature Communications

Volume: 15, P: 1-15
Unveiling the atomistic mechanism of oxide scale spalling in heat-resistant alloys

The good adhesion of scales is crucial for safe service of alloys. This study reveals that trace sulfur impurities can cause severe interface segregation and premature cracking, and such a detrimental effect can be prevented by micro alloying.

Congcong Li
Wenjin Zheng
Zhaoping Lu
ResearchOpen Access07 Mar 2025
Nature Communications

Volume: 16, P: 1-7
Structure of the full-length glucagon class B G-protein-coupled receptor

The crystal structure of the full-length human glucagon receptor reveals the essential role of the 12-residue ‘stalk’ segment and an extracellular loop in the regulation of ligand binding and receptor activation.

Haonan Zhang
Anna Qiao
Beili Wu
Research17 May 2017
Nature

Volume: 546, P: 259-264
An experimental study on the synergic damage of chemical solutions and stress to coal

Yaoyu Shi
Xiangchun Li
Qingdong Qu
ResearchOpen Access23 Jan 2025
Scientific Reports

Volume: 15, P: 1-17
Evaluation on coupling coordinated development of population economy and eco-geological environment in the twin-city economic circle of Chengdu–Chongqing region

Dong Han
Liang Chen
Ming Chang
ResearchOpen Access18 Aug 2023
Scientific Reports

Volume: 13, P: 1-17
The associations of physical activity patterns and the triglyceride-glucose index in US adults: a secondary data analysis of NHANES (2007–2018)

JinYe Zhang
YiLin Yang
Bin Yu
ResearchOpen Access18 Jan 2025
Scientific Reports

Volume: 15, P: 1-13
Structure of the glucagon receptor in complex with a glucagon analogue

The crystal structure of the full-length glucagon receptor in complex with a glucagon analogue NNC1702 reveals how the peptide ligand interacts with its target and shows the conformational changes required for receptor activation.

Haonan Zhang
Anna Qiao
Beili Wu
Research04 Jan 2018
Nature

Volume: 553, P: 106-110
Endothelial CDS2 deficiency causes VEGFA-mediated vascular regression and tumor inhibition

Wencao Zhao
Le Cao
Weijun Pan
ResearchOpen Access09 Sept 2019
Cell Research

Volume: 29, P: 895-910
Association of gastrointestinal microbiome and obesity with gestational diabetes mellitus-an updated globally based review of the high-quality literatures

Jiahui Li
Min Wang
Shuli Yang
ReviewsOpen Access21 May 2024
Nutrition & Diabetes

Volume: 14, P: 1-11