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Showing 1–50 of 190 results

Advanced filters: Author: Hiroshi Tamura Clear advanced filters

Author Correction: Photoproximity labeling of endogenous receptors in the live mouse brain in minutes

Mikiko Takato
Seiji Sakamoto
Itaru Hamachi
Amendments and Corrections29 Jan 2026
Nature Chemical Biology

P: 1
Formation of silver mirror by photolysis of thin films of high molecular weight silver compounds

YOSHIAKI KONISHI
HIROSHI SAIJO
MIKIO TAMURA
Research25 Aug 1977
Nature

Volume: 268, P: 709-710
Heterogeneous photocatalytic reduction of dichromate on n-type semiconductor catalysts

Hiroshi Yoneyama
Yukiyasu Yamashita
Hideo Tamura
Research20 Dec 1979
Nature

Volume: 282, P: 817-818
Disentangling multiple gas kinematic drivers in the Perseus galaxy cluster

Kinematic measurements of the Perseus galaxy cluster reveal two drivers of gas motions: a small-scale driver in the inner core associated with black-hole feedback and a large-scale driver in the outer core powered by mergers.

Marc Audard
Hisamitsu Awaki
Elena Bellomi
Research28 Jan 2026
Nature

P: 1-5
Chlorine and potassium enrichment in the Cassiopeia A supernova remnant

XRISM observations show the presence of odd-numbered elements chlorine and potassium in Cas A. These findings suggest that stellar activity plays an important role in cosmic chemical evolution, enriching space with elements vital for planets and life.

Marc Audard
Hisamitsu Awaki
Manan Agarwal
ResearchOpen Access04 Dec 2025
Nature Astronomy

Volume: 10, P: 144-153
DNA analysis of two patients with a non-fluorescent y chromosome

Takashi Sekine
Keiko Fukutani
Yasuo Nakagome
Research01 Jun 1992
Japanese journal of human genetics

Volume: 37, P: 157-162
Stratified wind from a super-Eddington X-ray binary is slower than expected

The XRISM Resolve spectrum of the galactic neutron star X-ray binary, GX 13+1, reveals one of the densest winds ever seen in absorption lines.

Marc Audard
Hisamitsu Awaki
Missagh Mehdipour
ResearchOpen Access17 Sept 2025
Nature

Volume: 646, P: 57-61
Lifetime risk, sex and age differences in annual incidence of ocular motor cranial nerve palsy in Japan for 2019

Miyata et al. examine the incidence rates and lifetime risk of ocular motor cranial nerve palsy (OMCNP) in in a nationwide, population-based cohort study in Japan for 2019. Finding reveals that OMCNP incidence rate increases with age and is higher in men, and that approximately one in 100 individuals is affected in their lifetime.

Manabu Miyata
Ai Kido
Akitaka Tsujikawa
ResearchOpen Access19 Jul 2025
Communications Medicine

Volume: 5, P: 1-6
Gut microbial factors predict disease severity in a mouse model of multiple sclerosis

Gut microbiota factors including IgA coating can predict disease severity in a mouse model of multiple sclerosis.

Alex Steimle
Mareike Neumann
Mahesh S. Desai
ResearchOpen Access15 Jul 2024
Nature Microbiology

Volume: 9, P: 2244-2261
Autonomous synchronization of the circadian KaiC phosphorylation rhythm

Hiroshi Ito
Hakuto Kageyama
Takao Kondo
Research28 Oct 2007
Nature Structural & Molecular Biology

Volume: 14, P: 1084-1088
Identification of an orally active small-molecule PTHR1 agonist for the treatment of hypoparathyroidism

Hypoparathyroidism and osteoporosis can be treated with parathyroid hormone, but frequent injections are required. Here the authors develop a small-molecule agonist for the parathyroid hormone type I receptor that can be administered orally, and demonstrate its efficacy in rats.

Tatsuya Tamura
Hiroshi Noda
Yoshiki Kawabe
ResearchOpen Access18 Nov 2016
Nature Communications

Volume: 7, P: 1-14
A New Method of Treating Light-Scattering Data on Dilute Polymer Solutions

Hiroshi Fujita
Research01 Sept 1970
Polymer Journal

Volume: 1, P: 537-541
Selective Inhibition of Acyl-CoA:cholesterol Acyltransferase 2 Isozyme by Flavasperone and Sterigmatocystin from Aspergillus Species

Kent Sakai
Satoshi Ohte
Hiroshi Tomoda
Research01 Sept 2008
The Journal of Antibiotics

Volume: 61, P: 568-572
Infrared Spectroscopic Approaches to Polymer Transitions. II. The Transition of Hydrogen Bonding in Styrene–Methacrylic Acid (St–MAA) Copolymers

Katsuyuki Ogura
Hiroshi Sobue
Research01 Mar 1972
Polymer Journal

Volume: 3, P: 153-158
Synthesis of the Polymer with Polar Side Groups. I. The Syntheses and Polymerizations of 2-(2, 2-Dicyanoethylene)-2, 3-dihydropyran, 2-2(-Cyano-2-carboethoxyethylene)-2, 3-dihydropyran and 2-(2, 2-Dicarboalkoxyethylene)-2, 3-dihydropyran

Yasuo Oshiro
Yasuhiko Shirota
Hiroshi Mikawa
Research01 Mar 1972
Polymer Journal

Volume: 3, P: 217-225
Structured ionized winds shooting out from a quasar at relativistic speeds

Observations of a luminous quasar from the high-resolution spectrometer Resolve aboard XRISM revealed highly inhomogeneous wind structure outflowing from a supermassive black hole, which probably consists of up to a million clumps.

Marc Audard
Hisamitsu Awaki
Yerong Xu
Research14 May 2025
Nature

Volume: 641, P: 1132-1136
Loss of NDRG2 expression activates PI3K-AKT signalling via PTEN phosphorylation in ATLL and other cancers

The PI3K pathway that encompasses the tumour suppressor PTEN contributes to tumourigenesis in adult T-cell leukaemia-lymphoma (ATLL). In this study, Nakahata et al. show that PTEN is dephosphorylated by NDRG2, and that loss of NDGR2 in ATLL results in the activation of the PI3K pathway.

Shingo Nakahata
Tomonaga Ichikawa
Kazuhiro Morishita
Research26 Feb 2014
Nature Communications

Volume: 5, P: 1-15
Spatial dynamics of CD39⁺CD8⁺ exhausted T cell reveal tertiary lymphoid structures-mediated response to PD-1 blockade in esophageal cancer

Immune checkpoint blockade (ICB) benefits esophageal squamous cell cancer, but the immune cell mediators remain unclear. Here the author show, by imaging mass cytometry, that CD39⁺CD8⁺ exhausted cells are present abundantly in both tertiary lymphoid tissue and tumor and correlate with responses to ICB.

Kenro Tanoue
Hirofumi Ohmura
Eishi Baba
ResearchOpen Access19 Oct 2024
Nature Communications

Volume: 15, P: 1-18
Translational genomics of osteoarthritis in 1,962,069 individuals

A genome-wide association study meta-analysis combined with multiomics data of osteoarthritis identifies 700 effector genes as well as biological processes with a convergent involvement of multiple effector genes; 10% of these genes express the target of approved drugs.

Konstantinos Hatzikotoulas
Lorraine Southam
Eleftheria Zeggini
ResearchOpen Access09 Apr 2025
Nature

Volume: 641, P: 1217-1224
Photoproximity labeling of endogenous receptors in the live mouse brain in minutes

Takato et al. developed a light-driven, singlet oxygen-mediated proximity labeling method termed PhoxID to identify the local proteomes of endogenously expressed neuronal receptors in the genetically intact live mouse brain.

Mikiko Takato
Seiji Sakamoto
Itaru Hamachi
Research01 Aug 2024
Nature Chemical Biology

Volume: 21, P: 109-119
RNA-binding proteins of KHDRBS and IGF2BP families control the oncogenic activity of MLL-AF4

The establishment of a mouse model of MLL-AF4-induced leukaemia is a challenge as the introduction of fusion gene of human MLL-AF4 does not cause leukaemia in mice. Here the authors reveal that MLL-AF4 is post-transcriptionally regulated by RNA-binding proteins that inhibits MLL-AF4 translation, thus, hampering MLL-AF4-mediated leukemic transformation.

Hiroshi Okuda
Ryo Miyamoto
Akihiko Yokoyama
ResearchOpen Access05 Nov 2022
Nature Communications

Volume: 13, P: 1-15
Food odor perception promotes systemic lipid utilization

Prior to consuming a meal, food-odor perception is sufficient to trigger systemic lipid utilization in male mice.

Hiroshi Tsuneki
Masanori Sugiyama
Toshiyasu Sasaoka
Research14 Nov 2022
Nature Metabolism

Volume: 4, P: 1514-1531
The bulk motion of gas in the core of the Centaurus galaxy cluster

X-ray spectroscopic observations of the Centaurus galaxy cluster with the X-Ray Imaging and Spectroscopy Mission satellite show that the hot gas flows along the line of sight relative to the central galaxy.

Marc Audard
Hisamitsu Awaki
Anwesh Majumder
Research12 Feb 2025
Nature

Volume: 638, P: 365-369
Direct Copolymerization of CO₂ and Diols

Masazumi Tamura
Kazuki Ito
Keiichi Tomishige
ResearchOpen Access14 Apr 2016
Scientific Reports

Volume: 6, P: 1-9
Pallister-Killian syndrome: Cytogenetic and biochemical studies

Kouji Narahara
Yoshiharu Wakita
Hiroshi Kimoto
Research01 Sept 1988
Japanese journal of human genetics

Volume: 33, P: 339-347
Subnuclear gene positioning through lamina association affects copper tolerance

The nuclear lamina regulates chromatin organization and gene positioning. Here the authors show that CROWDED NUCLEI proteins contribute to the meshwork lamina structure in Arabidopsis nuclei and regulate copper tolerance by promoting lamina association and expression of copper response genes.

Yuki Sakamoto
Mayuko Sato
Sachihiro Matsunaga
ResearchOpen Access20 Nov 2020
Nature Communications

Volume: 11, P: 1-12
A circumstellar disk associated with a massive protostellar object

Zhibo Jiang
Motohide Tamura
Ji Yang
Research01 Sept 2005
Nature

Volume: 437, P: 112-115
Deletion of skeletal muscle Akt1/2 causes osteosarcopenia and reduces lifespan in mice

Sasako et al. show that disruption of the insulin/IGF-1 signaling by suppressing Akt activity in mouse skeletal muscle can accelerate osteosarcopenia and shortens lifespan, which is reversed by inactivation of FoxOs rather than activation of mTOR, suggesting FoxOs as therapeutic targets.

Takayoshi Sasako
Toshihiro Umehara
Kohjiro Ueki
ResearchOpen Access05 Oct 2022
Nature Communications

Volume: 13, P: 1-18
Mutational spectrum of hepatitis C virus in patients with chronic hepatitis C determined by single molecule real-time sequencing

Fumiyasu Nakamura
Haruhiko Takeda
Hiroshi Seno
ResearchOpen Access30 Apr 2022
Scientific Reports

Volume: 12, P: 1-13
Differences between pathologic and non-pathologic high myopia in 4-year outcomes of anti-VEGF therapy for macular neovascularization

Yuki Honda
Manabu Miyata
Akitaka Tsujikawa
ResearchOpen Access11 Jun 2024
Scientific Reports

Volume: 14, P: 1-7
Altered sulfation status of FAM20C-dependent chondroitin sulfate is associated with osteosclerotic bone dysplasia

Raine syndrome is associated with loss-of-function mutations of FAM20C. Here we show that Raine-originated mutations abrogate the interaction between FAM20C and C4ST-1 to alter chondroitin sulfate sulfation status and impact biomineralization in vitro and bone mineral density in vivo in mouse models, thereby serving clues for Raine syndrome etiology.

Toshiyasu Koike
Tadahisa Mikami
Hiroshi Kitagawa
ResearchOpen Access26 Dec 2022
Nature Communications

Volume: 13, P: 1-15
Comparative analysis of necrotizing enterocolitis in preterm infants born in Japan and born to mothers of Japanese ethnicity in California

Satoshi Kusuda
Mihoko V. Bennett
Asao Yara
ResearchOpen Access22 Mar 2025
Scientific Reports

Volume: 15, P: 1-11
Nuclear actin assembly is an integral part of decidualization in human endometrial stromal cells

Nuclear actin assembly occurs during decidualization of human endometrial stromal cells. This contributes to cell differentiation by inducing cell cycle arrest for establishing the decidualized state of endometrial stromal cells.

Isao Tamura
Kei Miyamoto
Norihiro Sugino
ResearchOpen Access11 Jul 2024
Communications Biology

Volume: 7, P: 1-14
Formation and branch migration of Holliday junctions mediated by eukaryotic recombinases

Although the bacterial RecA protein has been previously described to facilitate reciprocal duplex DNA exchange, here the first eukaryotic proteins, yeast Rhp51 and human Rad51, are demonstrated to catalyse this process.

Yasuto Murayama
Yumiko Kurokawa
Hiroshi Iwasaki
Research06 Feb 2008
Nature

Volume: 451, P: 1018-1021
NIRS external dose estimation system for Fukushima residents after the Fukushima Dai-ichi NPP accident

Keiichi Akahane
Shunsuke Yonai
Makoto Akashi
ResearchOpen Access17 Apr 2013
Scientific Reports

Volume: 3, P: 1-6
Common dysfunctional variants of ABCG2 have stronger impact on hyperuricemia progression than typical environmental risk factors

Akiyoshi Nakayama
Hirotaka Matsuo
Nariyoshi Shinomiya
ResearchOpen Access09 Jun 2014
Scientific Reports

Volume: 4, P: 1-5
Synthesis and Polymerization of New Spirophosphoranes Having Five- and Six-Membered Rings

Shiro Kobayashi
Jun-ichi Kadokawa
Hiroshi Uyama
Research01 Jul 1992
Polymer Journal

Volume: 24, P: 699-702
Secondary Stress Relaxation Mechanism in Ion-Containing Polymers I. A New Analytical Method

Hiroshi Matsuura
Research01 Dec 1986
Polymer Journal

Volume: 18, P: 1027-1035
Hydrogen-Transfer Alternating Copolymerization of P-Ethenyl-N-n-propylphosphonamidic Acid Ethyl Ester with Cyclic Phosphonites Involving Oxidation-Reduction Process

Shiro Kobayashi
Jun-ichi Kadokawa
Shin-ichiro Shoda
Research01 Sept 1991
Polymer Journal

Volume: 23, P: 1099-1104
Equations of State for Poly(vinylidene fluoride)

Hiroshi Tanaka
Koichi Takayama
Tetuo Takemura
Research01 Sept 1982
Polymer Journal

Volume: 14, P: 719-727
Synthesis of Polydimethylsiloxane-Grafted Fluoropolymers and Properties for Hydrophobic Materials

Hiroshi Suzuki
Toru Kobayashi
Makoto Takeishi
Research01 May 2000
Polymer Journal

Volume: 32, P: 447-451
Effects of sacubitril/valsartan according to daily salt intake and comparison with thiazide add-on treatment in patients with uncontrolled hypertension

Kyoji Chiba
Mari Sotozawa
Akira Kanamori
Research14 Nov 2025
Hypertension Research

Volume: 49, P: 486-498
Annual trends of ophthalmic surgeries in Japan’s super-aged society, 2014–2020: a national claims database study

Saori Wada
Masahiro Miyake
Akitaka Tsujikawa
ResearchOpen Access18 Dec 2023
Scientific Reports

Volume: 13, P: 1-8
Therapeutic effects of faricimab on aflibercept-refractory age-related macular degeneration

Ryosuke Tamiya
Masayuki Hata
Akitaka Tsujikawa
ResearchOpen Access30 Nov 2023
Scientific Reports

Volume: 13, P: 1-8
Glycan sulfation patterns define autophagy flux at axon tip via PTPRσ-cortactin axis

Sulfation of chondroitin sulfate and heparan sulfate dictates their abilities to promote axon growth via regulating the binding to the phosphatase PTPRσ and the consequences on phosphorylation of the cortactin component of the autophagy machinery.

Kazuma Sakamoto
Tomoya Ozaki
Kenji Kadomatsu
Research06 May 2019
Nature Chemical Biology

Volume: 15, P: 699-709
High-throughput functional evaluation of BRCA2 variants of unknown significance

Many germline variants are found in the BRCA2 gene, some of which pre-dispose women to breast and ovarian cancer. Here, the authors develop a method to determine the functional significance of BRCA2 variants and show that it is comparable to the IARC system of classifying variants.

Masachika Ikegami
Shinji Kohsaka
Hiroyuki Mano
ResearchOpen Access22 May 2020
Nature Communications

Volume: 11, P: 1-13
Parkinson’s disease-associated ATP13A2/PARK9 functions as a lysosomal H⁺,K⁺-ATPase

Mutations in the human ATP13A2, a lysosomal ATPase, is associated with pathogenesis of Parkinson’s disease. Here, the authors show that ATP13A2 functions as H + /K + transporting protein, preventing lysosomal alkalinization and α-synuclein accumulation.

Takuto Fujii
Shushi Nagamori
Hideki Sakai
ResearchOpen Access20 Apr 2023
Nature Communications

Volume: 14, P: 1-11
An NEFH founder mutation causes broad phenotypic spectrum in multiple Japanese families

Masahiro Ando
Yujiro Higuchi
Hiroshi Takashima
Research28 Jan 2022
Journal of Human Genetics

Volume: 67, P: 399-403
Macular atrophy at 5 years after photodynamic therapy for polypoidal choroidal vasculopathy

Kentaro Kawai
Manabu Miyata
Akitaka Tsujikawa
Research14 Apr 2022
Eye

Volume: 37, P: 1067-1072
Differentiation between non-small cell lung cancer and radiation pneumonitis after carbon-ion radiotherapy by ¹⁸F-FDG PET/CT texture analysis

Makito Suga
Ryuichi Nishii
Tatsuya Higashi
ResearchOpen Access01 Jun 2021
Scientific Reports

Volume: 11, P: 1-9

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