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Showing 1–50 of 354 results

Advanced filters: Author: J Waxman Clear advanced filters

CD4⁺ T cells mediate CAR-T cell-associated immune-related adverse events after BCMA CAR-T cell therapy

An in-depth analysis of tissue biopsies from patients with multiple myeloma and CAR T cell therapy-associated immune-related adverse events (CirAEs) after treatment with commercial BCMA-targeted CAR T cell therapy shows that CD4⁺ CAR T cells mediate off-tumor toxicities and that high CD4:CD8 ratio at apheresis, robust early CAR T cell expansion, ICANS and ciltacabtagene autoleuce treatment are independently associated with the development of CirAEs.

Matthew Ho
Luca Paruzzo
Joseph A. Fraietta
Research15 Jan 2026
Nature Medicine

P: 1-15
Correction: Mucosal ablation of Barrett esophagus

Irving Waxman
Vani J. A. Konda
Amendments and Corrections01 Apr 2010
Nature Reviews Gastroenterology & Hepatology

Volume: 7, P: 182
Identity of the 19S 'prosome' particle with the large multifunctional protease complex of mammalian cells (the proteasome)

Andre-Patrick Arrigo
Keiji Tanaka
William J. Welch
Research01 Jan 1988
Nature

Volume: 331, P: 192-194
Conduction properties of central demyelinated and remyelinated axons, and their relation to symptom production in demyelinating disorders

Kenneth J Smith
Research01 Mar 1994
Eye

Volume: 8, P: 224-237
Impact of liver P450 reductase suppression on cyclophosphamide activation, pharmacokinetics and antitumoral activity in a cytochrome P450-based cancer gene therapy model

Zeqi Huang
Malay K Raychowdhury
David J Waxman
Research15 Jul 2000
Cancer Gene Therapy

Volume: 7, P: 1034-1042
Proteome-wide association study of prostate cancer risk across populations

Prostate cancer incidence and mortality rates vary across males from diverse populations. Here, the authors perform a proteome-wide association study across different populations and establish population-specific genetic prediction models.

Hua Zhong
Jingjing Zhu
Lang Wu
ResearchOpen Access06 Dec 2025
Nature Communications

P: 1-11
Clustering of ion channels at the node of Ranvier

L.C. Fritz
J.P. Brockes
News & Views21 May 1981
Nature

Volume: 291, P: 190-191
Pharmaceutical patent challenges — time for reassessment?

Gregory Glass
Reviews01 Dec 2004
Nature Reviews Drug Discovery

Volume: 3, P: 1057-1062
Tertiary structural similarity between a class A β-lactamase and a penicillin-sensitive D-alanyl carboxypeptidase-transpeptidase

B. Samraoui
B. J. Sutton
D. C. Phillips
Research27 Mar 1986
Nature

Volume: 320, P: 378-380
Sodium channel density in hypomyelinated brain increased by myelin basic protein gene deletion

J. L. Noebels
P. K. Marcom
M. H. Jalilian-Tehrani
Research01 Aug 1991
Nature

Volume: 352, P: 431-434
Chondrodysplasia and neurological abnormalities in ATF-2-deficient mice

Andreas M. Reimold
Michael J. Grusby
Laurie H. Glimcher
Research18 Jan 1996
Nature

Volume: 379, P: 262-265
Sr isotopic fractionation in Ca–Al inclusions from the Allende meteorite

P. J. Patchett
Research31 Jan 1980
Nature

Volume: 283, P: 438-441
Popovic rebuts

Barbara J. Culliton
News26 Sept 1991
Nature

Volume: 353, P: 288-289
Human lung-cancer-cell radioresistance investigated through 2D network topology

Luca Tirinato
Valentina Onesto
Francesco Gentile
ResearchOpen Access28 Jul 2022
Scientific Reports

Volume: 12, P: 1-14
Recent Orange and Purple Book legislation suggests a need to bridge drug and biologic patent regimes

Additional changes could make the registries of drug patents published by the FDA, called the Orange and Purple Books, more useful and reduce barriers to effective competition from generic and biosimilar drugs.

Bryan S. Walsh
Jonathan J. Darrow
Aaron S. Kesselheim
Comments & Opinion15 Feb 2022
Nature Biotechnology

Volume: 40, P: 167-169
CCR5-targeted allogeneic gamma–delta CD19 chimeric antigen receptor T cells for HIV-associated B cell-malignancy immunotherapy

CCR5-deficient gamma–delta CD19 CAR T cells show resistance to HIV-mediated depletion and antitumour efficacy in B cell malignancies.

Ángel Ramírez-Fernández
Alexander J. Dimitri
Joseph A. Fraietta
Research21 Oct 2025
Nature Biomedical Engineering

P: 1-15
Fetal-Tissue Research: Abortion Politics Slow Advances to a Crawl

B.J. Spalding
Research01 Jul 1991
Bio/Technology

Volume: 9, P: 615-616
Genome-scale CRISPR screens identify PTGES3 as a direct modulator of androgen receptor function in advanced prostate cancer

Genome-wide CRISPRi screens for modulators of androgen receptor (AR) protein levels using live-cell quantitative endogenous AR fluorescence reporters identify PTGES3 as a new regulator of AR stability and function in prostate cancer.

Haolong Li
James E. Melnyk
Felix Y. Feng
ResearchOpen Access05 Nov 2025
Nature Genetics

Volume: 57, P: 3027-3038
The effects of gonadotrophin releasing hormone analogues in prostate cancer are mediated through specific tumour receptors

A Qayum
W Gullick
J Waxman
Research01 Jul 1990
British Journal of Cancer

Volume: 62, P: 96-99
The current status of scientific research and hormonal treatments for carcinoma of the prostate

J Waxman
A Saini
Editorial01 Sept 1991
British Journal of Cancer

Volume: 64, P: 419-421
Apoptosis and delayed degeneration after spinal cord injury in rats and monkeys

Maria J. Crowe
Jacqueline C. Bresnahan
Michael S. Beattie
Research01 Jan 1997
Nature Medicine

Volume: 3, P: 73-76
Respiratory viral infections awaken metastatic breast cancer cells in lungs

Mouse models show that respiratory infections from viruses such as influenza and SARS-CoV-2 can trigger metastasis of dormant breast cancer cells in the lungs, a finding supported by epidemiological data from two large human cohorts.

Shi B. Chia
Bryan J. Johnson
James DeGregori
ResearchOpen Access30 Jul 2025
Nature

Volume: 645, P: 496-506
SpaceBar enables single-cell-resolution clone tracing with imaging-based spatial transcriptomics

SpaceBar is a cellular barcoding strategy for simultaneous analysis of cell clonal and spatial identities.

Grant Kinsler
Caitlin Fagan
Yael Heyman
Research18 Dec 2025
Nature Methods

P: 1-6
Prevention of HIV-1 IIIB infection in chimpanzees by CD4 immunoadhesin

Rebecca H. R. Ward
Daniel J. Capon
Jorg W. Eichberg
Research01 Aug 1991
Nature

Volume: 352, P: 434-436
Political strategies for climate and environmental solutions

Many of the barriers to progress in addressing environmental problems, such as climate change, are political. This Review illustrates how insight into politics can help policymakers craft strategies to address the ambition gap, the implementation gap and the international action gap.

Jonas Meckling
Valerie J. Karplus
Reviews04 May 2023
Nature Sustainability

Volume: 6, P: 742-751
The energetic afterglow of the γ-ray burst of 14 December 1997

A. N. Ramaprakash
S. R. Kulkarni
L. Nicastro
Research07 May 1998
Nature

Volume: 393, P: 43-46
Effects of induced hypothermia on somatosensory evoked potentials in patients with chronic spinal cord injury

K C Hayes
J T C Hsieh
A R Blight
Research01 Nov 1993
Spinal Cord

Volume: 31, P: 730-741
Radio emission from the unusual supernova 1998bw and its association with the γ-ray burst of 25 April 1998

S. R. Kulkarni
D. A. Frail
J. S. Bloom
Research15 Oct 1998
Nature

Volume: 395, P: 663-669
Biceps vs extensor carpi radialis recovery in Frankel grades A and B in spinal cord injury patients

L M Kornsgold
G J Herbison
J F Ditunno
Research01 May 1994
Spinal Cord

Volume: 32, P: 340-348
Experimental demonstration of logical magic state distillation

Magic state distillation is achieved with logical qubits on a neutral-atom quantum computer using a dynamically reconfigurable architecture for parallel quantum operations.

Pedro Sales Rodriguez
John M. Robinson
Sergio H. Cantú
Research14 Jul 2025
Nature

Volume: 645, P: 620-625
The induction of tumour immunity in mice using glutaraldehyde-treated tumour cells

C. J. SANDERSON
P. FROST
Research19 Apr 1974
Nature

Volume: 248, P: 690-691
X-ray pulses from globular clusters

J. N. BAHCALL
J. P. OSTRIKER
Research01 Jul 1976
Nature

Volume: 262, P: 37-38
Structure of a Zn²⁺-containing D-alanyl-D-alanine-cleaving carboxypeptidase at 2.5 Å resolution

O. Dideberg
P. Charlier
J. M. Ghuysen
Research30 Sept 1982
Nature

Volume: 299, P: 469-470
Effect of zinc on haemoglobin binding by red blood cell membranes

SUMITRA DASH
GEORGE J. BREWER
FRED J. OELSHLEGEL JUN.
Research19 Jul 1974
Nature

Volume: 250, P: 251-252
Early chemotherapy in prostate cancer

Despite substantial improvement in the survival data for patients with prostate cancer, almost half of men with localized disease are not cured by surgery or radiation. In this Review Mazhar and Waxman assess the potential of using chemotherapy early in the natural history of prostate cancer.

Danish Mazhar
Jonathan Waxman
Reviews01 Sept 2008
Nature Clinical Practice Urology

Volume: 5, P: 486-493
Zoladex: Endocrine and therapeutic effects in post-menopausal breast cancer

AL Harris
J Carmichael
M Dowsett
Research01 Jan 1989
British Journal of Cancer

Volume: 59, P: 97-99
Direction of self-motion is perceived from optical flow

William H. Warren Jr
Daniel J. Hannon
Research10 Nov 1988
Nature

Volume: 336, P: 162-163
Isolation by molecular cloning of a fragment of the split ovalbumin gene

A. C. Garapin
J. P Lepennec
P. Kourilsky
Research01 Jun 1978
Nature

Volume: 273, P: 349-354
Are reverse payments and pay-for-delay settlements business as usual or an anticompetitive practice?

Cash payments and other arrangements between patent holders and their competitors in exchange for a delayed market entry interfere with free-market principles and keep product prices at a premium, which affects payers, governments, healthcare providers and especially patients.

Swati Shah
Matthew A Silva
Michael J Malloy
Comments & Opinion12 Jul 2016
Nature Biotechnology

Volume: 34, P: 716-719
Integra v. Merck: A mixed bag for research tool patents

Although the decision is good news for owners of patents relating to discovery tools, it is too early to predict the full impact of the case.

Charles Raubicheck
Barry S White
Pamela Fekete
Comments & Opinion01 Sept 2003
Nature Biotechnology

Volume: 21, P: 1099-1101
Atypical response to all-trans retinoic acid in a der(5)t(5;17) acute promyelocytic leukemia

M-J Mozziconacci
C Liberatore
M Lafage-Pochitaloff
Research12 Jun 1999
Leukemia

Volume: 13, P: 862-868
Demonstration of intermolecular forces in cell adhesion using a new electrochemical technique

D. GINGELL
J. A. FORNES
Research17 Jul 1975
Nature

Volume: 256, P: 210-211
The emergence of agbiogenerics

Although the first major agbiotech product patent has expired, regulatory requirements could continue to allot a significant degree of control to the original right holder.

David J Jefferson
Gregory D Graff
Alan B Bennett
Comments & Opinion07 Aug 2015
Nature Biotechnology

Volume: 33, P: 819-823
An absence of neutrinos associated with cosmic-ray acceleration in γ-ray bursts

An upper limit has been placed on the flux of energetic neutrinos associated with γ-ray bursts that is at least a factor of 3.7 below the predictions, implying either that γ-ray bursts are not the only sources of high-energy cosmic rays or that the efficiency of neutrino production is much lower than has been predicted.

R. Abbasi
Y. Abdou
M. Zoll
Research18 Apr 2012
Nature

Volume: 484, P: 351-354
Remission of postmenopausal breast cancer during treatment with the luteinising hormone releasing hormone agonist ICI 118630

P N Plowman
R I Nicholson
K J Walker
Research01 Dec 1986
British Journal of Cancer

Volume: 54, P: 903-909
Clinton courts research hospitals

Barbara J. Culliton
News31 Mar 1994
Nature

Volume: 368, P: 381
Preclinical trial of 4-aminopyridine in patients with chronic spinal cord injury

K C Hayes
A R Blight
J T Hamilton
Research01 Apr 1993
Spinal Cord

Volume: 31, P: 216-224
Serum metalloproteinases and their inhibitors: markers for malignant potential

T Baker
S Tickle
J Waxman
Research01 Sept 1994
British Journal of Cancer

Volume: 70, P: 506-512
Apoptosis-associated signaling pathways are required for chemotherapy-mediated female germ cell destruction

Gloria I. Perez
C. Michael Knudson
Jonathan L. Tilly
Research01 Nov 1997
Nature Medicine

Volume: 3, P: 1228-1232
Bcl-2 Family Gene Expression during Severe Hyperoxia Induced Lung Injury

Michael A O'Reilly
Rhonda J Staversky
Gloria S Pryhuber
Research01 Dec 2000
Laboratory Investigation

Volume: 80, P: 1845-1854

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