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Showing 551–600 of 720 results

Advanced filters: Author: JOHN A. FREEMAN Clear advanced filters

Wild birds prefer to eat the more familiar of artificial morphs that are similar in colour

John A Allen
Research01 Dec 1984
Heredity

Volume: 53, P: 705-715
Oscillations of frequency in batesian mimics, hawks and doves, and other simple frequency dependent polymorphisms

John R G Turner
Research01 Aug 1980
Heredity

Volume: 45, P: 113-126
Lung microbiota associations with clinical features of COPD in the SPIROMICS cohort

Kristopher Opron
Lesa A. Begley
Yvonne J. Huang
ResearchOpen Access05 Feb 2021
npj Biofilms and Microbiomes

Volume: 7, P: 1-10
The role of fecal elastase-1 in detecting exocrine pancreatic disease

Exocrine pancreatic disease is thought to be uncommon; however, several conditions are associated with exocrine pancreatic insufficiency and it perhaps occurs more frequently than is conventionally expected. A reliable, patient-friendly, cheap and easy to use test for exocrine pancreatic disease is yet to be established. This Review examines the role of fecal-elastase 1 testing in detecting exocrine pancreatic insufficiency in a number of conditions and determines the value of pancreatic enzyme supplementation in these settings.

John S. Leeds
Kofi Oppong
David S. Sanders
Reviews31 May 2011
Nature Reviews Gastroenterology & Hepatology

Volume: 8, P: 405-415
Intracellular zinc protects tumours from T cell-mediated cytotoxicity

Emily J. Lelliott
Jonathan Naddaf
Jane Oliaro
ResearchOpen Access11 Sept 2024
Cell Death & Differentiation

Volume: 31, P: 1707-1716
Heritabilities for antler characteristics and body weight in yearling white-tailed deer

John D Williams
W F Krueger
Donnie H Harmel
Research01 Jul 1994
Heredity

Volume: 73, P: 78-83
Eukaryotic initiation factor-4E in superficial and muscle invasive bladder cancer and its correlation with vascular endothelial growth factor expression and tumour progression

J P Crew
S Fuggle
A L Harris
ResearchOpen Access10 Dec 1999
British Journal of Cancer

Volume: 82, P: 161-166
Selection component analysis of the Mpi locus in the amphipod Platorchestia platensis

John H McDonald
Research01 Apr 1989
Heredity

Volume: 62, P: 243-249
Non-reversible tissue fixation retains extracellular vesicles for in situ imaging

Tissue fixation with formaldehyde and a water-soluble carbodiimide crosslinker (EDC) leads to retention of extracellular vesicles within tissues and allows for reliable extracellular vesicle imaging for semiquantitative imaging applications.

Mrinali P. Gupta
Sangeetha Tandalam
John T. G. Pena
Research11 Nov 2019
Nature Methods

Volume: 16, P: 1269-1273
Endothelial cell–based systemic gene therapy of metastatic melanoma

John O Ojeifo
Hyeran R Lee
James A Zwiebel
Research11 Oct 2001
Cancer Gene Therapy

Volume: 8, P: 636-648
Variation in wild populations of Papaver dubium VI. Dominance relationships for genes controlling metrical characters

A E Arthur
M S Rana
M J Lawrence
Research01 Apr 1973
Heredity

Volume: 30, P: 177-187
Human BAG-1/RAP46 protein is generated as four isoforms by alternative translation initiation and overexpressed in cancer cells

Xiaolong Yang
Garry Chernenko
Shou-Ching Tang
Research04 Sept 1998
Oncogene

Volume: 17, P: 981-989
731 PRENATAL DIAGNOSIS OF β-THALASSEMIA BY AMNIO-CENTESIS

Halg H Kazazian Jr.
Corlnne D Boehm
Maurice J Mahoney
Research01 Apr 1981
Pediatric Research

Volume: 15, P: 564
Size-related and geographic variation at two enzyme loci in Megalorchestia californiana (Amphipoda: Talitridae)

John H McDonald
Research01 Jun 1985
Heredity

Volume: 54, P: 359-366
Genome size variation among north american minnows (Cyprinidae). I. distribution of the variation in five species

John R Gold
H James Price
Research01 Jun 1985
Heredity

Volume: 54, P: 297-305
Microgeographic genetic variation in the haploid and diploid stages of the moss Polytrichum juniperinum Hedw.

David J Innes
Research01 Jun 1990
Heredity

Volume: 64, P: 331-340
Increased sensitivity to the prodrug 5'-deoxy-5-fluorouridine and modulation of 5-fluoro-2'-deoxyuridine sensitivity in MCF-7 cells transfected with thymidine phosphorylase

AV Patterson
H Zhang
AL Harris
Research01 Sept 1995
British Journal of Cancer

Volume: 72, P: 669-675
C3G is tyrosine-phosphorylated after integrin-mediated cell adhesion in normal but not in Bcr/Abl expressing cells

Ron de Jong
Arnoud van Wijk
John Groffen
Research24 Nov 1998
Oncogene

Volume: 17, P: 2805-2810
Urine-free response criteria predict progression-free survival in multiple myeloma: a post hoc analysis of BMT CTN 0702

Rahul Banerjee
Amber R. Fritz
Marcelo C. Pasquini
Research24 Feb 2025
Leukemia

Volume: 39, P: 1001-1004
NIH Centers for Accelerated Innovations Program: principles, practices, successes and challenges

Commercializing innovations in academic environments is notoriously challenging. Here, we describe the progress of the NIH Centers for Accelerated Innovations program — initiated in 2013 to address these challenges — which we believe could help set a new standard for the early-stage commercialization of biomedical innovations in academic environments.

Elliott M. Antman
Paul E. Di Corleto
Lesley Watts
Comments & Opinion04 Aug 2017
Nature Reviews Drug Discovery

Volume: 16, P: 663-664
Author Correction: c-Rel orchestrates energy-dependent epithelial and macrophage reprogramming in fibrosis

Jack Leslie
Marina García Macia
Fiona Oakley
Amendments and Corrections10 Dec 2020
Nature Metabolism

Volume: 3, P: 118-119
Genomic analysis of early-stage lung cancer reveals a role for TP53 mutations in distant metastasis

Debra Van Egeren
Khushi Kohli
Zenta Walther
ResearchOpen Access09 Nov 2022
Scientific Reports

Volume: 12, P: 1-6
Author Correction: Germline variation at 8q24 and prostate cancer risk in men of European ancestry

Marco Matejcic
Edward J. Saunders
Christopher A. Haiman
Amendments and CorrectionsOpen Access17 Jan 2019
Nature Communications

Volume: 10, P: 1-5
Comparative performances of machine learning methods for classifying Crohn Disease patients using genome-wide genotyping data

Alberto Romagnoni
Simon Jégou
Pamela Whittaker
ResearchOpen Access17 Jul 2019
Scientific Reports

Volume: 9, P: 1-18
Simulated deep space exposure on seeds utilizing the MISSE flight facility

Jeffrey T. Richards
Todd E. Mortenson
Ye Zhang
ResearchOpen Access17 Jan 2025
npj Microgravity

Volume: 11, P: 1-11
Genome-wide association study of glioma subtypes identifies specific differences in genetic susceptibility to glioblastoma and non-glioblastoma tumors

Beatrice Melin, Richard Houlston, Melissa Bondy and colleagues report results of a large-scale genome-wide association study of glioma. They identify five new risk loci for glioblastoma and eight new risk loci for non-glioblastoma tumors, highlighting distinct genetic etiologies for these two glioma subtypes.

Beatrice S Melin
Jill S Barnholtz-Sloan
Melissa L Bondy
Research27 Mar 2017
Nature Genetics

Volume: 49, P: 789-794
E2F and STAT3 provide transcriptional synergy for histone variant H2AZ activation to sustain glioblastoma chromatin accessibility and tumorigenicity

Jeehyun Yoon
Oleg V. Grinchuk
Derrick Sek Tong Ong
ResearchOpen Access20 Jan 2022
Cell Death & Differentiation

Volume: 29, P: 1379-1394
The impact of transient air pollution exposure on worker performance in Chinese soccer players

Ning Zhang
Xiahai Wei
Richard B. Freeman
ResearchOpen Access28 Dec 2024
Scientific Reports

Volume: 14, P: 1-10
Biologic therapies in non-rheumatic diseases: lessons for rheumatologists?

The use of biologic agents has revolutionized treatment in a number of rheumatic and non-rheumatic autoimmune and inflammatory disorders. In this Review, the authors discuss whether rheumatologists can learn lessons from the application of biologic agents in non-rheumatic diseases such as psoriasis, asthma and multiple sclerosis.

Gillian M. Bell
Gary Reynolds
John D. Isaacs
Reviews02 Aug 2011
Nature Reviews Rheumatology

Volume: 7, P: 507-516
Reviews

B John
Reviews01 Nov 1962
Heredity

Volume: 17, P: 593-594
The germinal center kinase (GCK)-related protein kinases HPK1 and KHS are candidates for highly selective signal transducers of Crk family adapter proteins

Wolf Oehrl
Christian Kardinal
Stephan M Feller
Research14 Oct 1998
Oncogene

Volume: 17, P: 1893-1901
Adenovirus-mediated expression of HSV1-TK or Fas ligand induces cell death in primary human glioma-derived cell cultures that are resistant to the chemotherapeutic agent CCNU

Tricia C Maleniak
John L Darling
Maria G Castro
Research11 Sept 2001
Cancer Gene Therapy

Volume: 8, P: 589-598
Partial self-fertilization and inbreeding depression in two populations of Mimulus guttatus

John H Willis
Research01 Aug 1993
Heredity

Volume: 71, P: 145-154
A composite critical-size rabbit mandibular defect for evaluation of craniofacial tissue regeneration

This protocol describes the study design, surgical procedure, postoperative care and analysis techniques necessary to produce a preclinical rabbit model of large bone and tooth defects in the mandible, for use in a wide range of areas in craniofacial tissue engineering.

Sarita R Shah
Simon Young
Antonios G Mikos
Protocols22 Sept 2016
Nature Protocols

Volume: 11, P: 1989-2009
A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1

Richard Trembath, Peter Donnelly and colleagues report a genome-wide association study identifying six new psoriasis susceptibility loci. They also identify a statistical interaction between HLA-C and ERAP1 in psoriasis susceptibility.

Amy Strange
Francesca Capon
Richard C Trembath
Research17 Oct 2010
Nature Genetics

Volume: 42, P: 985-990
A new stress sensor and risk factor for suicide: the T allele of the functional genetic variant in the GABRA6 gene

Xenia Gonda
Jane Sarginson
Gyorgy Bagdy
ResearchOpen Access10 Oct 2017
Scientific Reports

Volume: 7, P: 1-13
The National Human Activity Pattern Survey (NHAPS): a resource for assessing exposure to environmental pollutants

NEIL E KLEPEIS
WILLIAM C NELSON
WILLIAM H ENGELMANN
Research26 Jul 2001
Journal of Exposure Science & Environmental Epidemiology

Volume: 11, P: 231-252
BAP1: a novel ubiquitin hydrolase which binds to the BRCA1 RING finger and enhances BRCA1-mediated cell growth suppression

David E Jensen
Monja Proctor
Frank J Rauscher III
Research10 Mar 1998
Oncogene

Volume: 16, P: 1097-1112
Coupling of the murine protein tyrosine phosphatase PEST to the epidermal growth factor (EGF) receptor through a Src homology 3 (SH3) domain-mediated association with Grb2

Alain Charest
John Wagner
Michel L Tremblay
Research10 Apr 1997
Oncogene

Volume: 14, P: 1643-1651
Upregulation of GALNT7 in prostate cancer modifies O-glycosylation and promotes tumour growth

Emma Scott
Kirsty Hodgson
Jennifer Munkley
ResearchOpen Access01 Feb 2023
Oncogene

Volume: 42, P: 926-937
Targeting the ERG oncogene with splice-switching oligonucleotides as a novel therapeutic strategy in prostate cancer

Ling Li
Lisa Hobson
Michael Ladomery
ResearchOpen Access25 Jun 2020
British Journal of Cancer

Volume: 123, P: 1024-1032
A polygenic resilience score moderates the genetic risk for schizophrenia

Jonathan L. Hess
Daniel S. Tylee
Stephen J. Glatt
ResearchOpen Access06 Sept 2019
Molecular Psychiatry

Volume: 26, P: 800-815
COVID-19 due to the B.1.617.2 (Delta) variant compared to B.1.1.7 (Alpha) variant of SARS-CoV-2: a prospective observational cohort study

Kerstin Kläser
Erika Molteni
Emma L. Duncan
ResearchOpen Access28 Jun 2022
Scientific Reports

Volume: 12, P: 1-17
Genomic epidemiology of SARS-CoV-2 in a university outbreak setting and implications for public health planning

Sema Nickbakhsh
Joseph Hughes
Alison Smith-Palmer
ResearchOpen Access19 Jul 2022
Scientific Reports

Volume: 12, P: 1-17
Rare germline copy number variants (CNVs) and breast cancer risk

Dennis et al. investigate potential breast cancer associations with rare germline copy number variants (CNVs) by conducting a genome-wide analysis in a large breast cancer case-control dataset. The authors detected associations with exonic deletions in established breast cancer susceptibility genes and suggestive associations for a number of non-coding CNVs.

Joe Dennis
Jonathan P. Tyrer
Douglas F. Easton
ResearchOpen Access18 Jan 2022
Communications Biology

Volume: 5, P: 1-15
Book reviews

John Gosden
Books & Arts01 Dec 1994
Heredity

Volume: 73, P: 681-682
The Cancer Genome Atlas Pan-Cancer analysis project

Current clinical practice is organized according to tissue or organ of origin of tumors. Now, The Cancer Genome Atlas (TCGA) Research Network has started to identify genomic and other molecular commonalities among a dozen different types of cancer. Emerging similarities and contrasts will form the basis for targeted therapies of the future and for repurposing existing therapies by molecular rather than histological similarities of the diseases.

Kyle Chang
Chad J Creighton
Joshua M Stuart
Comments & OpinionOpen Access26 Sept 2013
Nature Genetics

Volume: 45, P: 1113-1120
Regulatory gene adaptation: An evolutionary model

Philip W Hedrick
John F McDonald
Research01 Aug 1980
Heredity

Volume: 45, P: 83-97
Reactive astrocyte nomenclature, definitions, and future directions

Good–bad binary classifications fail to describe reactive astrocytes in CNS disorders. Here, 81 researchers reach consensus on widespread misconceptions and provide definitions and recommendations for future research on reactive astrocytes.

Carole Escartin
Elena Galea
Alexei Verkhratsky
Reviews15 Feb 2021
Nature Neuroscience

Volume: 24, P: 312-325
Characterization by Electrospray Mass Spectrometry of Human Ca²⁺–sensitive Cytosolic Phospholipase A₂ Produced in Baculovirus–infected Insect Cells

Gerald W. Becker
James R. Miller
Ruth M. Kramer
Research01 Jan 1994
Bio/Technology

Volume: 12, P: 69-74

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