Trujillo et al. identify scavenger receptor class B type I (SR-B1) as a keratinocyte marker of skin inflammation and a potential therapeutic target. Topically delivered HDL-like nanoparticles target SR-B1, reduce inflammatory signaling in keratinocytes, and improve imiquimod-induced inflammation in murine models.
- Jacquelyn Trujillo
- Andrea E. Calvert
- C. Shad Thaxton
