Nature Search

Virus-inspired lipopeptide-derived nucleic acid delivery to cartilage for osteoarthritis therapy

Cartilage-targeted gene therapy is dependent on delivery efficiency. Here, the authors develop non-pathogenic, virus-inspired lipopeptide-based nanoplatforms to deliver nucleic acids to cartilage with increased transfection efficiency over conventional lipid nanoparticles.

Yu Fu
Yulan Huang
Chong Li
ResearchOpen Access16 Oct 2025
Nature Communications

Volume: 16, P: 1-18
Extracellular traps from activated vascular smooth muscle cells drive the progression of atherosclerosis

Vascular smooth muscle cells (VSMCs) are known for their fate plasticity in atherosclerosis plaque progression. Here, Zhai et al. show that extracellular traps generated from CD68 ⁺ VSMCs adversely contribute to plaque progression and highlight their unexpected role in plaque stability by regulating the direction of VSMC trans-differentiation.

Ming Zhai
Shiyu Gong
Wenhui Peng
ResearchOpen Access06 Dec 2022
Nature Communications

Volume: 13, P: 1-15
Publisher Correction: Small molecule agonist of mitochondrial fusion repairs mitochondrial dysfunction

Yingjie Guo
Huan Zhang
Quan Chen
Amendments and Corrections22 Feb 2023
Nature Chemical Biology

Volume: 19, P: 530
Analytical study on steady seepage of a foundation pit adjacent to a structure

Jiayun Liang
Hai Liu
Xilian Wen
ResearchOpen Access08 May 2025
Scientific Reports

Volume: 15, P: 1-18
Sclerothrapy of giant lymphatic malformation in neonates

Fan Hu
Fan Ma
Jiayun Yu
ResearchOpen Access23 Sept 2024
Journal of Perinatology

Volume: 45, P: 213-217
A chromosome-level genome assembly of the Chinese herbal medicine Chelidonium majus

Xialian Bu
Xianqi Peng
Jiayun Yao
ResearchOpen Access14 Oct 2025
Scientific Data

Volume: 12, P: 1-8
Small molecule agonist of mitochondrial fusion repairs mitochondrial dysfunction

Guo et al. report a small molecule agonist of mitochondrial fusion that activates MFN1, an outer mitochondrial membrane protein, and protects cells from mitochondrial damage and ischemia/reperfusion injury in a mouse model.

Yingjie Guo
Huan Zhang
Quan Chen
Research12 Jan 2023
Nature Chemical Biology

Volume: 19, P: 468-477
Technology adoption and extreme stock risk: Evidence from digital tax reform in China

Kangqi Jiang
Xiaofeng Chen
Mengling Zhou
ResearchOpen Access06 Feb 2025
Humanities and Social Sciences Communications

Volume: 12, P: 1-20
The risk effects of corporate digitalization: exacerbate or mitigate?

Kangqi Jiang
Lulu Chen
Xinyi Du
ResearchOpen Access05 Mar 2025
Humanities and Social Sciences Communications

Volume: 12, P: 1-19
Perovskite superlattices with efficient carrier dynamics

Fabrication of a low-dimensional metal halide perovskite superlattice by chemical epitaxy is reported, with a criss-cross two-dimensional network parallel to the substrate, leading to efficient carrier transport in three dimensions.

Yusheng Lei
Yuheng Li
Sheng Xu
Research10 Aug 2022
Nature

Volume: 608, P: 317-323
Insights and approaches using deep learning to classify wildlife

Zhongqi Miao
Kaitlyn M. Gaynor
Wayne M. Getz
ResearchOpen Access31 May 2019
Scientific Reports

Volume: 9, P: 1-9
TREM2 macrophage promotes cardiac repair in myocardial infarction by reprogramming metabolism via SLC25A53

Shiyu Gong
Ming Zhai
Wenhui Peng
ResearchOpen Access05 Jan 2024
Cell Death & Differentiation

Volume: 31, P: 239-253
Implantation underneath the abdominal anterior rectus sheath enables effective and functional engraftment of stem-cell-derived islets

A new transplantation site in the abdomen, the subanterior rectus sheath, is shown to allow for functional maturation of stem-cell-derived islet cells and improved glycemic control in a proof-of-principle study involving four nonhuman primates.

Zhen Liang
Dong Sun
Hongkui Deng
Research09 Jan 2023
Nature Metabolism

Volume: 5, P: 29-40
Relumino mode may provide video terminal assistance for the amblyopic patients

Jiayun Yu
Yiting Sun
Xiuming Jin
ResearchOpen Access01 Jul 2025
Scientific Reports

Volume: 15, P: 1-9
Shanxi province food security evaluation research

Jiayun Wang
Mingyu Tong
ResearchOpen Access06 Jan 2025
Scientific Reports

Volume: 15, P: 1-13
Artificial intelligence models utilize lifestyle factors to predict dry eye related outcomes

Andrew D. Graham
Jiayun Wang
Meng C. Lin
ResearchOpen Access18 Apr 2025
Scientific Reports

Volume: 15, P: 1-10
Author Correction: Inhibition of A20 expression in tumor microenvironment exerts anti-tumor effect through inducing myeloid-derived suppressor cells apoptosis

Bin Shao
Xiawei Wei
Yuquan Wei
Amendments and CorrectionsOpen Access16 Mar 2023
Scientific Reports

Volume: 13, P: 1-2
Knowledge mapping of vocational education and training research (2004–2020): a visual analysis based on CiteSpace

Yumi Tian
Jiayun Liu
Xueshi Wu
ResearchOpen Access15 Dec 2023
Scientific Reports

Volume: 13, P: 1-15
Inhibition of A20 expression in tumor microenvironment exerts anti-tumor effect through inducing myeloid-derived suppressor cells apoptosis

Bin Shao
Xiawei Wei
Yuquan Wei
ResearchOpen Access12 Nov 2015
Scientific Reports

Volume: 5, P: 1-13
Predicting demographics from meibography using deep learning

Jiayun Wang
Andrew D. Graham
Meng C. Lin
ResearchOpen Access20 Sept 2022
Scientific Reports

Volume: 12, P: 1-11
Metagenome and metabolome insights into the energy compensation and exogenous toxin degradation of gut microbiota in high-altitude rhesus macaques (Macaca mulatta)

Junsong Zhao
Yongfang Yao
Huailiang Xu
ResearchOpen Access20 Apr 2023
npj Biofilms and Microbiomes

Volume: 9, P: 1-17
Carotid plaque and bone density and microarchitecture in psoriatic arthritis: the correlation with soluble ST2

Jiayun Shen
Qing Shang
Lai-Shan Tam
ResearchOpen Access24 Aug 2016
Scientific Reports

Volume: 6, P: 1-8
Dynamic Covalent Chemistry-based Sensing: Pyrenyl Derivatives of Phenylboronic Acid for Saccharide and Formaldehyde

Xingmao Chang
Jiayun Fan
Yu Fang
ResearchOpen Access08 Aug 2016
Scientific Reports

Volume: 6, P: 1-9
Mapping of 10-km daily diffuse solar radiation across China from reanalysis data and a Machine-Learning method

Qinghai Qi
Jinyang Wu
Ming Zhang
ResearchOpen Access11 Jul 2024
Scientific Data

Volume: 11, P: 1-13

Search

Virus-inspired lipopeptide-derived nucleic acid delivery to cartilage for osteoarthritis therapy

Extracellular traps from activated vascular smooth muscle cells drive the progression of atherosclerosis

Publisher Correction: Small molecule agonist of mitochondrial fusion repairs mitochondrial dysfunction

Analytical study on steady seepage of a foundation pit adjacent to a structure

Sclerothrapy of giant lymphatic malformation in neonates

A chromosome-level genome assembly of the Chinese herbal medicine Chelidonium majus

Small molecule agonist of mitochondrial fusion repairs mitochondrial dysfunction

Technology adoption and extreme stock risk: Evidence from digital tax reform in China

The risk effects of corporate digitalization: exacerbate or mitigate?

Perovskite superlattices with efficient carrier dynamics

Insights and approaches using deep learning to classify wildlife

TREM2 macrophage promotes cardiac repair in myocardial infarction by reprogramming metabolism via SLC25A53

Implantation underneath the abdominal anterior rectus sheath enables effective and functional engraftment of stem-cell-derived islets

Relumino mode may provide video terminal assistance for the amblyopic patients

Shanxi province food security evaluation research

Artificial intelligence models utilize lifestyle factors to predict dry eye related outcomes

Author Correction: Inhibition of A20 expression in tumor microenvironment exerts anti-tumor effect through inducing myeloid-derived suppressor cells apoptosis

Knowledge mapping of vocational education and training research (2004–2020): a visual analysis based on CiteSpace

Inhibition of A20 expression in tumor microenvironment exerts anti-tumor effect through inducing myeloid-derived suppressor cells apoptosis

Predicting demographics from meibography using deep learning

Metagenome and metabolome insights into the energy compensation and exogenous toxin degradation of gut microbiota in high-altitude rhesus macaques (Macaca mulatta)

Carotid plaque and bone density and microarchitecture in psoriatic arthritis: the correlation with soluble ST2

Dynamic Covalent Chemistry-based Sensing: Pyrenyl Derivatives of Phenylboronic Acid for Saccharide and Formaldehyde

Mapping of 10-km daily diffuse solar radiation across China from reanalysis data and a Machine-Learning method

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