Nature Search

Author Correction: UKB-MDRMF: a multi-disease risk and multimorbidity framework based on UK biobank data

Yukang Jiang
Bingxin Zhao
Hongtu Zhu
Amendments and CorrectionsOpen Access28 Jan 2026
Nature Communications

Volume: 17, P: 1
Concerted 1,3-migration through regiodivergent consecutive 1,2-rearrangements using palladium catalysis

Concerted 1,3-alkyl shifts are often challenging due to antiaromatic transition states and geometric strain. Now, a formal 1,3-migration can be achieved through two consecutive 1,2-shifts—a Pd(II)-catalysed semi-pinacol rearrangement followed by a 1,2-C/Pd(IV) dyotropic rearrangement. This two-step process transforms 1-vinylcyclobutanols into fluorinated cyclohexanones or cyclohexenones, depending on the reaction conditions.

Jing Gong
Qian Wang
Jieping Zhu
Research30 Jan 2026
Nature Synthesis

P: 1-9
Elucidating the role of interfacial charge transfer on the oxygen incorporation/evolution reactions for solid oxide cells

Solid oxide cells are limited by slow oxygen exchange reaction kinetics at the oxygen electrode. Operando X-ray absorption and electrochemical analysis show that surface modification with a praseodymium oxide layer induces interfacial charge transfer and accelerates the surface kinetics.

Kaichuang Yang
Jieping Zheng
Qiyang Lu
ResearchOpen Access11 Dec 2025
Nature Communications

Volume: 16, P: 1-10
Unified divergent strategy towards the total synthesis of the three sub-classes of hasubanan alkaloids

Several Hasubanan alkaloids have been synthesized in the past decades, however a divergent approach to access the 3 subclasses of such natural products has not been reported yet. Here, the authors show the enantioselective total syntheses of four representative members via a unified strategy leading to the three topologically different classes of alkaloids.

Guang Li
Qian Wang
Jieping Zhu
ResearchOpen Access04 Jan 2021
Nature Communications

Volume: 12, P: 1-7
UKB-MDRMF: a multi-disease risk and multimorbidity framework based on UK biobank data

The accumulation of biomedical cohort data offers opportunities to better understand disease mechanisms. Here, the authors present UKB-MDRMF, a framework that predicts health risks for 1,560 diseases using data from the UK Biobank data.

Yukang Jiang
Bingxin Zhao
Hongtu Zhu
ResearchOpen Access22 Apr 2025
Nature Communications

Volume: 16, P: 1-16
N-alkylated polydithiocarbamates derived from thiocarbonyl fluoride as macro-photoiniferters for living 3D printing

Polydithiocarbamates represent a unique class of sulfur-containing polymers possessing advanced functionalities but their structural and functional exploration is limited by significant synthetic challenges. Here, the authors report a versatile synthetic strategy enabling access to previously inaccessible N-alkylated polydithiocarbamates.

Pengfei Ruan
Haonan Xiang
Jieping Wang
ResearchOpen Access01 Jul 2025
Nature Communications

Volume: 16, P: 1-8
Copper-catalyzed remote C(sp³)–H azidation and oxidative trifluoromethylation of benzohydrazides

Functionalization of carbon radicals formed via 1,5-hydrogen atom transfer of amidyl radicals is an underdeveloped protocol for remote C–H functionalization. Here, the authors report a Cu-catalyzed γ-azidation and oxidative δ-trifluoromethylation of benzohydrazides for the synthesis of more functionalized amides.

Xu Bao
Qian Wang
Jieping Zhu
ResearchOpen Access15 Feb 2019
Nature Communications

Volume: 10, P: 1-7
Functionalization of remote C(sp³)-H bonds enabled by copper-catalyzed coupling of O-acyloximes with terminal alkynes

Sonogashira cross-coupling is a powerful strategy to prepare functionalized internal alkynes. Here, the authors report a domino sequence for the generation of γ-/δ-alkynyl nitriles and γ-alkynyl ketones from the coupling of terminal alkynes with O-acyloximes derived from cycloalkanones and acylic ketones, respectively.

Zhaodong Li
Rubén O. Torres-Ochoa
Jieping Zhu
ResearchOpen Access21 Jan 2020
Nature Communications

Volume: 11, P: 1-7
CRX is an intrinsic suppressor of epithelial‒mesenchymal transition in retinal pigment epithelial cells: a promising therapeutic avenue for subretinal fibrosis

Dongli Li
Qingjian Ou
Haibin Tian
ResearchOpen Access31 Dec 2025
Cell Death & Disease

Volume: 17, P: 1-15
EMP1 safeguards hematopoietic stem cells by suppressing sphingolipid metabolism and alleviating endoplasmic reticulum stress

A new study shows EMP1 protects hematopoietic stem cells by suppressing sphingolipid metabolism and ER stress. EMP1 interacts with CERS2 to limit dihydroceramide production, which causes protein aggregation when elevated.

Lei Li
Yufei Lei
Yu Hou
ResearchOpen Access07 Jul 2025
Nature Communications

Volume: 16, P: 1-20
Generalized biological foundation model with unified nucleic acid and protein language

He and colleagues develop LucaOne, a biological foundation model pre-trained on nucleic acid and protein sequences from 169,861 species. It shows an emerging understanding of molecular biology’s central dogma, enhancing bioinformatics analysis and helping explore unknown aspects of molecular biology.

Yong He
Pan Fang
Zhaorong Li
ResearchOpen Access18 Jun 2025
Nature Machine Intelligence

Volume: 7, P: 942-953
Copper-catalyzed methylative difunctionalization of alkenes

While the trifluoromethylative difunctionalization of unactivated alkenes has been largely explored, methylative difunctionalization remains underinvestigated. Here, the authors report copper-catalyzed alkoxy- and azido-methylation reactions of alkenes leading to important synthetic building blocks and valuable O- and N-heterocycles.

Xu Bao
Takayuki Yokoe
Jieping Zhu
ResearchOpen Access13 Sept 2018
Nature Communications

Volume: 9, P: 1-8
Cordycepin prevents radiation ulcer by inhibiting cell senescence via NRF2 and AMPK in rodents

Radiation damage causes DNA foci to form and senescence, causing ulcers. Here, the authors show that a naturally occurring adenosine analogue, cordycepin, prevents cell senescence via an increase in AMPK/NRF2, so blocking ulcers caused by radiation on skin/intestine/tongue damage in rodents.

Ziwen Wang
Zelin Chen
Chunmeng Shi
ResearchOpen Access10 Jun 2019
Nature Communications

Volume: 10, P: 1-16
Clipping aneurysms via a fully endoscopic transcranial approach

Zhengxing Xie
Yan Zhuang
Jieping Liu
ResearchOpen Access30 Dec 2024
Scientific Reports

Volume: 14, P: 1-7
Taming the radical cation intermediate enabled one-step access to structurally diverse lignans

Lignans, in spite of their structural diversity, are all biosynthetically derived from coniferyl alcohol. Here, the authors describe a divergent and stereoselective chemical synthesis of three types of lignans from biomass-derived monolignols, exploiting the different reaction manifolds of highly reactive radical cation intermediate.

Jia-Chen Xiang
Cédric Fung
Jieping Zhu
ResearchOpen Access16 Jun 2022
Nature Communications

Volume: 13, P: 1-12
C–C bond activation enabled by dyotropic rearrangement of Pd(iv) species

Many C–C bond activation methods involve strain-releasing cleavage of small rings to compensate for unfavourable kinetics and thermodynamics. Now, the 1,2-positional interchange of vicinal C–C and C–Pd bonds has been reported, giving access to quaternary carbon–palladium bonds. This dyotropic rearrangement has been used for the enantioselective synthesis of functionalized fluorinated cyclopentanes.

Jian Cao
Hua Wu
Jieping Zhu
Research24 May 2021
Nature Chemistry

Volume: 13, P: 671-676
Synthesis and Characterization of Poly(ethylene-co-vinyl alcohol)-graft-poly(ε-caprolactone)

Hongjin Jiang
Junpo He
Yuliang Yang
Research01 Sept 2002
Polymer Journal

Volume: 34, P: 682-686
Crystallization and Morphology Development of Binary Crystalline Poly(ethylene succinate)/Poly(ethylene oxide) (PES/PEO) Blend with Non-Isothermal Crystallization

Shuangai He
Jieping Liu
Research17 Apr 2007
Polymer Journal

Volume: 39, P: 537-542
Genome-wide dissection of changes in maize root system architecture during modern breeding

The root-related changes in maize domestication, improvement and modern breeding were systematically investigated, and candidate genes related to maize root system architecture were identified for future genetic improvement.

Wei Ren
Longfei Zhao
Qingchun Pan
Research17 Nov 2022
Nature Plants

Volume: 8, P: 1408-1422
A novel LGALS1-depended and immune-associated fatty acid metabolism risk model in acute myeloid leukemia stem cells

Huanhuan Qin
Meixi Peng
Yu Hou
ResearchOpen Access05 Jul 2024
Cell Death & Disease

Volume: 15, P: 1-14
QTL analysis of modifiers for pigmentary disorder in rats carrying Ednrb^sl mutations

Jieping Huang
Ruihua Dang
Takashi Agui
ResearchOpen Access22 Jan 2016
Scientific Reports

Volume: 6, P: 1-8
Whole genome sequencing identifies pathogenic genetic variants in Han Chinese patients with familial venous thromboembolism

Whole-genome sequencing coupled with whole-exome sequencing validation in Han Chinese patients reveals a diverse genetic basis for venous thromboembolism, and identifies GP6, TET2, and JAK2 as novel risk factors in East Asian populations.

Zhu Zhang
Haobo Li
Chen Wang
ResearchOpen Access12 Apr 2025
Communications Biology

Volume: 8, P: 1-9
Combined use of a microbial restoration substrate and avirulent Ralstonia solanacearum for the control of tomato bacterial wilt

Xuefang Zheng
Yujing Zhu
Bo Liu
ResearchOpen Access27 Dec 2019
Scientific Reports

Volume: 9, P: 1-10
MEK inhibition prevents CAR-T cell exhaustion and differentiation via downregulation of c-Fos and JunB

Xiujian Wang
Xiao Tao
He Huang
ResearchOpen Access22 Oct 2024
Signal Transduction and Targeted Therapy

Volume: 9, P: 1-19
A spatiotemporal distribution prediction model for electric vehicles charging load in transportation power coupled network

Xiaolong Yang
Jingwen Yun
Zeqi Ge
ResearchOpen Access01 Feb 2025
Scientific Reports

Volume: 15, P: 1-30
Direct conversion of human umbilical cord mesenchymal stem cells into retinal pigment epithelial cells for treatment of retinal degeneration

Xiaoman Zhu
Zhiyang Chen
Haibin Tian
ResearchOpen Access12 Sept 2022
Cell Death & Disease

Volume: 13, P: 1-15
Genetic deconvolution of fetal and maternal cell-free DNA in maternal plasma enables next-generation non-invasive prenatal screening

Chenming Xu
Jianli Li
Jinglan Zhang
ResearchOpen Access13 Oct 2022
Cell Discovery

Volume: 8, P: 1-22
Mechanistic insights into manganese oxidation of a soil-borne Mn(II)-oxidizing Escherichia coli strain by global proteomic and genetic analyses

Zhiyong Wang
Jieping Wang
Lin Li
ResearchOpen Access02 May 2017
Scientific Reports

Volume: 7, P: 1-13
Effects of a microbial restoration substrate on plant growth and rhizosphere bacterial community in a continuous tomato cropping greenhouse

Xuefang Zheng
Ziran Wang
Bo Liu
ResearchOpen Access13 Aug 2020
Scientific Reports

Volume: 10, P: 1-11
Small molecules in the treatment of COVID-19

Sibei Lei
Xiaohua Chen
Ke Men
ReviewsOpen Access05 Dec 2022
Signal Transduction and Targeted Therapy

Volume: 7, P: 1-39
Glia maturation factor beta deficiency protects against diabetic osteoporosis by suppressing osteoclast hyperactivity

Si Shi
Huijie Gu
Lixia Lu
ResearchOpen Access01 May 2023
Experimental & Molecular Medicine

Volume: 55, P: 898-909
Cell-autonomous effect of cardiomyocyte branched-chain amino acid catabolism in heart failure in mice

Jia-yu Yu
Nancy Cao
Chen Gao
ResearchOpen Access29 Mar 2023
Acta Pharmacologica Sinica

Volume: 44, P: 1380-1390
Sox5 contributes to prostate cancer metastasis and is a master regulator of TGF-β-induced epithelial mesenchymal transition through controlling Twist1 expression

Jieping Hu
Jing Tian
Zhiqun Shang
ResearchOpen Access09 Nov 2017
British Journal of Cancer

Volume: 118, P: 88-97
Genomic architecture of fetal central nervous system anomalies using whole-genome sequencing

Ying Yang
Sheng Zhao
Xinlin Chen
ResearchOpen Access13 May 2022
npj Genomic Medicine

Volume: 7, P: 1-10
A missense mutation in Pitx2 leads to early-onset glaucoma via NRF2-YAP1 axis

Yeming Yang
Xiao Li
Xianjun Zhu
ResearchOpen Access29 Oct 2021
Cell Death & Disease

Volume: 12, P: 1-15
Integrated genomic analysis identifies deregulated JAK/STAT-MYC-biosynthesis axis in aggressive NK-cell leukemia

Liang Huang
Dan Liu
Qian-fei Wang
Research17 Nov 2017
Cell Research

Volume: 28, P: 172-186

Search

Author Correction: UKB-MDRMF: a multi-disease risk and multimorbidity framework based on UK biobank data

Concerted 1,3-migration through regiodivergent consecutive 1,2-rearrangements using palladium catalysis

Elucidating the role of interfacial charge transfer on the oxygen incorporation/evolution reactions for solid oxide cells

Unified divergent strategy towards the total synthesis of the three sub-classes of hasubanan alkaloids

UKB-MDRMF: a multi-disease risk and multimorbidity framework based on UK biobank data

N-alkylated polydithiocarbamates derived from thiocarbonyl fluoride as macro-photoiniferters for living 3D printing

Copper-catalyzed remote C(sp³)–H azidation and oxidative trifluoromethylation of benzohydrazides

Functionalization of remote C(sp³)-H bonds enabled by copper-catalyzed coupling of O-acyloximes with terminal alkynes

CRX is an intrinsic suppressor of epithelial‒mesenchymal transition in retinal pigment epithelial cells: a promising therapeutic avenue for subretinal fibrosis

EMP1 safeguards hematopoietic stem cells by suppressing sphingolipid metabolism and alleviating endoplasmic reticulum stress

Generalized biological foundation model with unified nucleic acid and protein language

Copper-catalyzed methylative difunctionalization of alkenes

Cordycepin prevents radiation ulcer by inhibiting cell senescence via NRF2 and AMPK in rodents

Clipping aneurysms via a fully endoscopic transcranial approach

Taming the radical cation intermediate enabled one-step access to structurally diverse lignans

C–C bond activation enabled by dyotropic rearrangement of Pd(iv) species

Synthesis and Characterization of Poly(ethylene-co-vinyl alcohol)-graft-poly(ε-caprolactone)

Crystallization and Morphology Development of Binary Crystalline Poly(ethylene succinate)/Poly(ethylene oxide) (PES/PEO) Blend with Non-Isothermal Crystallization

Genome-wide dissection of changes in maize root system architecture during modern breeding

A novel LGALS1-depended and immune-associated fatty acid metabolism risk model in acute myeloid leukemia stem cells

QTL analysis of modifiers for pigmentary disorder in rats carrying Ednrb^sl mutations

Whole genome sequencing identifies pathogenic genetic variants in Han Chinese patients with familial venous thromboembolism

Combined use of a microbial restoration substrate and avirulent Ralstonia solanacearum for the control of tomato bacterial wilt

MEK inhibition prevents CAR-T cell exhaustion and differentiation via downregulation of c-Fos and JunB

A spatiotemporal distribution prediction model for electric vehicles charging load in transportation power coupled network

Direct conversion of human umbilical cord mesenchymal stem cells into retinal pigment epithelial cells for treatment of retinal degeneration

Genetic deconvolution of fetal and maternal cell-free DNA in maternal plasma enables next-generation non-invasive prenatal screening

Mechanistic insights into manganese oxidation of a soil-borne Mn(II)-oxidizing Escherichia coli strain by global proteomic and genetic analyses

Effects of a microbial restoration substrate on plant growth and rhizosphere bacterial community in a continuous tomato cropping greenhouse

Small molecules in the treatment of COVID-19

Glia maturation factor beta deficiency protects against diabetic osteoporosis by suppressing osteoclast hyperactivity

Cell-autonomous effect of cardiomyocyte branched-chain amino acid catabolism in heart failure in mice

Sox5 contributes to prostate cancer metastasis and is a master regulator of TGF-β-induced epithelial mesenchymal transition through controlling Twist1 expression

Genomic architecture of fetal central nervous system anomalies using whole-genome sequencing

A missense mutation in Pitx2 leads to early-onset glaucoma via NRF2-YAP1 axis

Integrated genomic analysis identifies deregulated JAK/STAT-MYC-biosynthesis axis in aggressive NK-cell leukemia

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