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This study identifies viral poly(T) DNA as a key determinant of AIM2 inflammasome activation, revealing how viral genome variation shapes inflammatory responses and host survival during infection.

A cold-injection method based on pseudo-emulsion enables scalable synthesis of stable, pure-green perovskite nanocrystals with near-unity photoluminescence quantum yield, achieved through defect-suppressing slow polybromide plumbate assembly at cold temperatures.

Fluorine-containing binders in battery dry electrode processing raise environmental concerns regarding restrictions on per- and polyfluoroalkyl substances. Here, authors show that a fluorine-free binder, Parafilm, can be an alternative to enable primer-free high-loading electrodes with stable cycling for sustainable lithium-ion batteries.

An ultra-wide-field imaging Mueller matrix spectroscopic ellipsometry system with a 20 mm × 20 mm field of view was developed for semiconductor metrology. Over 10 million spectra were analyzed with machine learning, allowing wafer-scale variations to be identified and yield gains demonstrated.

Fabrication of fully stretchable organic light-emitting diodes incorporating an intrinsically stretchable exciplex-assisted phosphorescent layer along with MXene-contact stretchable electrodes is described, demonstrating high efficiency and mechanical compliance for applications in next-generation wearable and deformable displays.

Combining magnetic and optical control in a single system opens possibilities for spin-switchable optoelectronics. Herein, Dryzhakov et al. create a heterostructured magnetic/semiconducting system consisting of a 2D-superlattice perovskite (4,4-DFPD₂PbI₄) film with a cobalt layer and demonstrate a spin-switchable circularly polarized luminescence.

Perovskite nanocrystals are promising emitters but suffer from environmental instabilities. Here, Park et al. introduce aromatic nonpolar organogels as a soft passivating matrix of perovskites, demonstrating highly efficient and environmentally stable luminescent nanocomposites.

A new method ‘hypotaxy’ enables wafer-scale, single-crystal transition metal dichalcogenides growth directly on crystalline, lattice-mismatched and amorphous substrates.

Design of electrocatalyst in lithium sulfur batteries is important to improve electrochemical performance. Here, authors use protective carbon layer to modulate the metal p-band center and prevent undesirable phase change of electrocatalyst for realizing 1 A h level lithium sulfur pouch cell.

High-concentration lithium polysulfides in lean electrolyte lithium–sulfur batteries hinder stable cycling. Here, authors introduce a reversible calcium additive that regulates polysulfides chemistry and catalyzes sulfur redox reactions, improving energy density with stable cycling.

New two-dimensional semiconductors may exhibit properties beyond inherent semiconducting attributes. Here the authors report protonated semiconducting III–V-derived van der Waals crystals with memristive properties.

Using cryo-EM, authors reveal the structure and activation mechanism of GPR156, a class C orphan GPCR implicated in sound detection. They find that GPR156 is a transducer for phospholipid signaling and provide insights into the basis for its constitutive activation.

Quantification of supramolecular host–guest interactions is important for modulating supramolecular systems but accurately evaluating the adhesion energies of host–guest pairs remains challenging. Here, the authors directly quantify the interaction energies between cyclodextrin modified surfaces and ditopic adamantane using a surface force apparatus.

Engineering excitation wavelength of photosensitizers allows to enhanced reactive oxygen species but controlling the wavelength corresponding to operating conditions remains challenging. Here, the authors implement a wavelength-engineerable imidazolium-based porous organic polymer and demonstrate tuning of the optimal wavelength for maximum performance by modifying the linker system.

An electrodeposition method is proposed for the growth of elemental metal nanosheets with aligned grain orientation using a confined 2D template. Nucleation and growth are controlled within a confined 2D channel, resulting in nanosheets with high in-plane electrical anisotropy (>10³), highlighting their potential as switching elements.

A portable device integrating reverse transcription, fast thermocycling and in situ fluorescence detection accurately detects SARS-CoV-2 RNA in patient samples in 17 min.

Kim et al. report a strategy to reduce the dynamic disorder of the perovskite lattice by using CMMs that adsorb on the surface of PeNCs via van der Waals interactions and hydrogen bonding. The resulting pure green LEDs satisfying the Rec. 2020 color standard show a high EQE of 26.1%.

Minimally invasive cellular-level target-specific neuromodulation is needed to decipher brain function and neural circuitry. Here nano-magnetogenetics using magnetic force actuating nanoparticles has been reported, enabling wireless and remote stimulation of targeted deep brain neurons in freely behaving animals.

Magneto-gas vesicles, protein nanostructures with enhanced ultrasound signal and sensitivity, enable the non-invasive, long-term and quantitative monitoring of the mechanics of three-dimensional tissues and animals.

Photolithography is an established microfabrication technique but commonly uses costly shortwavelength light sources to achieve high resolution. Here the authors use metal patterns embedded in a flexible elastomer photomask with mechanical robustness for generation of subdiffraction patterns as a cost effective near-field optical printing approach.

Viologen-based 2D ionic covalent organic polymer (V-iCOP) thin films are synthesized via the Zincke reaction using three different linkers with varying electron affinities. The structural and electronic effects of the different linkers on the electrochromic device (ECD) performances are investigated and compared with theoretical DFT calculations. Due to the cationic viologen moiety, the V-iCOP films promote fast ionic diffusion with photocurable hydrogel electrolyte, with the ECD resulting in rapid switching (<10 s), high coloration efficiency (up to 836.08 cm² C⁻¹), low operating bias, multichromic behavior, and long-term cycling stability (92.5% retention after 2000 cycles).

The nanospace confinement of a magnetic nanoparticle within a porous cage, coupled with an encodable DNA clutch interface, enables a remotely powered and controlled rotary nanomotor that is autoresponsive to its microenvironment.

Neural systems are often bulky and heavy. Here, the authors produce a conformable neural interface for mice using liquid metals directly printed on the skull that can monitor neural activities with long-term stability.

A hybrid valley-centre tandem optical structure that combines perovskites and organic light-emitting diodes is demonstrated to obtain an efficient emitting device, showing the commercial potential of perovskite displays.

Conventional epitaxy is of limited application, but by placing a monolayer of graphene between the substrate and the so-called epilayer grown on top, its scope can be substantially extended.

On application of a focused magnetic field, zinc-doped iron oxide nanoparticles with targeting antibodies attached are shown to activate cell death signalling in a spatially controlled manner. This triggering of apoptosis signalling, via the magnetically activated aggregation of receptors, is observed in both in vitro and in vivo systems.

People living with HIV-1 are at an increased risk of developing various cancers. Here, the authors suggest that HIV-1-encoded Vpr can promote oncogenesis by forming a ternary complex with VprBP and Plk4 and inducing Plk4-dependent centriole overduplication and aneuploidy.

A modified bar-coating method enables the realization of efficient large-area perovskite light-emitting diodes with high uniformity.

Aerobic oxidation of propylene is a potential green route to propylene oxide production without the need for harmful oxidizing or wasteful sacrificial reagents. Here, a proof-of-concept integrated photo-electro-heterogeneous catalytic system performs this reaction using in situ-generated H₂O₂.

Multiple alternating layers of two-dimensional materials and epilayers are grown on III–N and III–V substrates in a single growth run. Then, each epilayer is harvested by mechanical exfoliation, producing multiple freestanding membranes from a single wafer.

Glucose oxidase (GOx) and horseradish peroxidase (HRP) are used as an enzymatic cascade for blood glucose monitoring. Here, the authors developed a metal-free, graphitic carbon nitride-based nanozyme with GOx- and HRP-like activities and combine it with a microfluidic reactor for real-time glucose monitoring.

A magnetic torque actuator has been developed and is capable of modulation of neurons expressing the mechanosensitive ion channel, Piezo1, resulting in long-distance control of locomotion of mice.

Replication-Factor-C (RFC) and RFC-like complexes (RLCs) mediate chromatin engagement of the proliferating cell nuclear antigen (PCNA). Here authors use biochemical and single molecule measurements to show that ATAD5-RLC has the most potent PCNA unloading activity and forms structurally distinct intermediates compared to RFC-PCNA.

The authors develop a method for the production of ultra-bright, efficient and stable perovskite light-emitting diodes, achieved with a simple in situ reaction process.

The properties of core–shell nanoparticles can be tuned so that they efficiently convert radiation into heat, leading to therapeutic results that are competitive with commercial drug treatments.