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Showing 1–14 of 14 results

Advanced filters: Author: Junfei Jin Clear advanced filters

Inhibiting macrophage-derived lactate transport restores cGAS–STING signalling and enhances antitumour immunity in glioblastoma

Li, Cui, Yang, Lu, Jiang, Zhang and colleagues identify a lactate transport mechanism from tumour-associated macrophages that regulates DNA repair and immune cell infiltration, which could be targeted to enhance immunotherapy efficacy in glioblastoma models.

Daqi Li
Gaoyuan Cui
Xiuxing Wang
Research06 Jan 2026
Nature Cell Biology

P: 1-14
Cancer, obesity, and diabetes: TKIs exert multiple effects on glucose homeostasis

Minglin Lin
Junfei Jin
Correspondence19 Apr 2017
Nature Reviews Clinical Oncology

Volume: 14, P: 268
The complement system is also important in immunogenic cell death

Junfei Jin
Songqing He
Correspondence28 Dec 2016
Nature Reviews Immunology

Volume: 17, P: 143
A structurally informed human protein–protein interactome reveals proteome-wide perturbations caused by disease mutations

Protein–protein interactomes incorporating structural data predict the functional consequences of disease mutations.

Dapeng Xiong
Yunguang Qiu
Haiyuan Yu
Research24 Oct 2024
Nature Biotechnology

Volume: 43, P: 1510-1524
Comprehensive characterization of protein–protein interactions perturbed by disease mutations

Human disease mutations affect protein–protein interfaces in a three-dimensional structurally resolved interaction network. Predicted oncoPPIs in cancer correlate with survival and drug sensitivity, and affect growth in vitro, supporting their relevance to disease pathogenesis.

Feixiong Cheng
Junfei Zhao
Joseph Loscalzo
Research08 Feb 2021
Nature Genetics

Volume: 53, P: 342-353
Opportunistic assessment of variations in tissue composition content using chest QCT

Jujia Li
Wei Zhang
Jian Zhao
ResearchOpen Access28 Jul 2025
Scientific Reports

Volume: 15, P: 1-11
Dissemination, divergence and establishment of H7N9 influenza viruses in China

Influenza surveillance over 15 cities across 5 provinces in China from October 2013 to July 2014 shows that the virus has diverged into distinct clades, becoming established in chickens and also disseminating to wider geographic regions.

Tommy Tsan-Yuk Lam
Boping Zhou
Huachen Zhu
Research11 Mar 2015
Nature

Volume: 522, P: 102-105
Aldo-keto Reductase Family 1 Member B 10 Mediates Liver Cancer Cell Proliferation through Sphingosine-1-Phosphate

Junfei Jin
Weijia Liao
Songqing He
ResearchOpen Access07 Mar 2016
Scientific Reports

Volume: 6, P: 1-11
Effects of enzymatic browning reaction on the usability of tobacco leaves and identification of components of reaction products

Yanjie Chen
Junfei Zhou
Yan Jin
ResearchOpen Access28 Nov 2019
Scientific Reports

Volume: 9, P: 1-24
Ceramide kinase-mediated C1P metabolism attenuates acute liver injury by inhibiting the interaction between KEAP1 and NRF2

Wei Dong
Qing Li
Junfei Jin
ResearchOpen Access01 Apr 2024
Experimental & Molecular Medicine

Volume: 56, P: 946-958
S1PR1 induces metabolic reprogramming of ceramide in vascular endothelial cells, affecting hepatocellular carcinoma angiogenesis and progression

Xuehong Wang
Zhidong Qiu
Junfei Jin
ResearchOpen Access06 Sept 2022
Cell Death & Disease

Volume: 13, P: 1-15
GBA1-dependent membrane glucosylceramide reprogramming promotes liver cancer metastasis via activation of the Wnt/β-catenin signalling pathway

Zhidong Qiu
Xuehong Wang
Junfei Jin
ResearchOpen Access30 May 2022
Cell Death & Disease

Volume: 13, P: 1-13
Trabid inhibits hepatocellular carcinoma growth and metastasis by cleaving RNF8-induced K63 ubiquitination of Twist1

Yuekun Zhu
Chao Qu
Zhiyong Zhang
ResearchOpen Access10 May 2018
Cell Death & Differentiation

Volume: 26, P: 306-320
A community effort to assess and improve drug sensitivity prediction algorithms

A community of researchers report the lessons learned from applying 44 algorithms to predict drug sensitivity in cancer cell lines using genomic, epigenetic and proteomic datasets

James C Costello
Laura M Heiser
Gustavo Stolovitzky
Research01 Jun 2014
Nature Biotechnology

Volume: 32, P: 1202-1212