Nature Search

Non-visual photoreceptive brain specification in sea urchin larvae

Here, they show that sea urchin larvae possess a non-visual, light-sensitive neural center with vertebrate-like molecular signatures, shedding light on the ancient origins of brain function in deuterostomes.

Junko Yaguchi
Koki Tsuyuzaki
Shunsuke Yaguchi
ResearchOpen Access19 Nov 2025
Nature Communications

Volume: 16, P: 1-13
A leukaemic cell mutant with a thermolabile alanyl-transfer RNA synthetase

KOKI SATO
Research30 Oct 1975
Nature

Volume: 257, P: 813-815
Associations of neuromelanin in the substantia nigra with antipsychotic response in schizophrenia

Ryosuke Tarumi
Shiori Honda
Shinichiro Nakajima
Research07 Nov 2025
Neuropsychopharmacology

Volume: 51, P: 682-690
TRBC1-CAR T cell therapy in peripheral T cell lymphoma: a phase 1/2 trial

In the dose-escalation part of the ongoing phase 1/2 LIBRA4 trial, patients with relapsed/refractory peripheral T cell lymphoma received T cell antigen receptor beta-chain constant domain 1 (TRBC1)-targeted chimeric antigen receptor T cell therapy, showing limited toxicity and encouraging preliminary clinical responses.

Kate Cwynarski
Gloria Iacoboni
Martin Pule
ResearchOpen Access11 Nov 2024
Nature Medicine

Volume: 31, P: 137-143
The DNA replication machinery transmits dual signals to prevent unscheduled licensing and execution of centrosome duplication

Cell division requires strict control of DNA replication and centrosome duplication. Here, the authors reveal that DNA replication machinery transmits dual signals to control proper timing of centrosome duplication for genome stability

Kyohei Matsuhashi
Kei K. Ito
Daiju Kitagawa
ResearchOpen Access08 Sept 2025
Nature Communications

Volume: 16, P: 1-18
CAR T or NK cells targeting mismatched HLA-DR molecules in acute myeloid leukemia after allogeneic hematopoietic stem cell transplant

Ikeda et al. report that HLA-DRB1 can serve as a leukemia-specific target for CAR T or natural killer cell-based therapy in patients with AML after allogeneic hematopoietic stem cell transplantation.

Shunya Ikeda
Kana Hasegawa
Naoki Hosen
Research24 Mar 2025
Nature Cancer

Volume: 6, P: 595-611
Immediate effect of physical activity on gut motility in healthy adults

Kento Katagiri
Soichiro Koyama
Shigeo Tanabe
ResearchOpen Access29 Sept 2025
Scientific Reports

Volume: 15, P: 1-9
PI3K-Akt signalling regulates Scx-lineage tenocytes and Tppp3-lineage paratenon sheath cells in neonatal tendon regeneration

While tendon healing is robust in children, adult tendon injuries are repaired with fibrotic scarring. Here they show that PI3K-Akt signaling plays a pivotal role in physiological neonatal tendon regeneration and regulates the stemness of both Scx-lineage tenocytes and Tppp3-lineage paratenon sheath cells.

Atsushi Goto
Shingo Komura
Haruhiko Akiyama
ResearchOpen Access20 Apr 2025
Nature Communications

Volume: 16, P: 1-18
Azilsartan causes natriuresis due to its sympatholytic action in kidney disease

Satoshi Kidoguchi
Naoki Sugano
Takashi Yokoo
Research28 May 2019
Hypertension Research

Volume: 42, P: 1507-1517
Genome-wide association study identifies 14 previously unreported susceptibility loci for adolescent idiopathic scoliosis in Japanese

Adolescent idiopathic scoliosis (AIS) is a common pediatric disease leading to spinal deformities. Here, the authors report GWAS followed by genome-wide meta-analysis in up to 79,211 Japanese individuals, identifying 20 genetic loci for AIS, 14 of which were previously unreported, and perform in vitro validation for rs1978060.

Ikuyo Kou
Nao Otomo
Shiro Ikegawa
ResearchOpen Access15 Aug 2019
Nature Communications

Volume: 10, P: 1-9
Safety and efficacy of laparoscopic repeat liver resection and re-operation for liver tumor

Koki Takase
Takuya Sakamoto
Kohei Murata
ResearchOpen Access02 Jun 2021
Scientific Reports

Volume: 11, P: 1-7
Sox2 is associated with cancer stem-like properties in colorectal cancer

Koki Takeda
Tsunekazu Mizushima
Hirofumi Yamamoto
ResearchOpen Access05 Dec 2018
Scientific Reports

Volume: 8, P: 1-9
The Cep57-pericentrin module organizes PCM expansion and centriole engagement

Centriole disengagement occurs towards mitotic exit and involves cleavage of pericentrin, a component of the pericentriolar material. Here the authors show that depletion of the centrosomal protein Cep57 leads to precocious centriole disengagement, and that Cep57 binds pericentrin.

Koki Watanabe
Daisuke Takao
Daiju Kitagawa
ResearchOpen Access25 Feb 2019
Nature Communications

Volume: 10, P: 1-13
Cep295 is a conserved scaffold protein required for generation of a bona fide mother centriole

Newly formed centrioles mature into functional mother centrioles. Here the authors show that the scaffolding protein Cep295 is recruited to the procentriole assembly site and assists daughter centriole assembly and daughter-to-mother centriole conversion.

Yuki Tsuchiya
Satoko Yoshiba
Daiju Kitagawa
ResearchOpen Access26 Aug 2016
Nature Communications

Volume: 7, P: 1-13
Association between amorphous calcium-phosphate ratios in circulating calciprotein particles and prognostic biomarkers in hemodialysis patients

Kimihiko Nakamura
Naohito Isoyama
Makoto Kuro-o
ResearchOpen Access29 Jul 2022
Scientific Reports

Volume: 12, P: 1-8
TRPV2 is critical for the maintenance of cardiac structure and function in mice

The TRPV2 calcium channel can be activated by mechanical stretch and may act as a mechanoreceptor in tissues. Here the authors deplete the TRPV2 calcium channel from the hearts of adult mice, showing that TRPV2 is important for the maintenance of cardiac structure and function.

Yuki Katanosaka
Keiichiro Iwasaki
Keiji Naruse
ResearchOpen Access29 May 2014
Nature Communications

Volume: 5, P: 1-14
Harnessing an integrated glyco-nanovaccine technology for enhanced cancer immunotherapy

Niimura et al. investigates the potential of an integrated glyco-nanovaccine (iGN) comprising gold nanoparticles conjugated with a synthetic Toll-like receptor 7 ligand, sugar chains, and peptide antigens for cancer immunotherapy. Treatment with iGN increases tumor-infiltrating CD8+ T cells and inhibits tumor growth.

Mayumi Niimura
Yasuhisa Sakamoto
Toshiro Moroishi
ResearchOpen Access29 Aug 2025
Communications Medicine

Volume: 5, P: 1-15
Unsupervised decomposition of natural monkey behavior into a sequence of motion motifs

Data-driven machine learning algorithm, Syntactic Motion Parser, automatically decomposes primate’s natural motion dynamics into its inherent component.

Koki Mimura
Jumpei Matsumoto
Takafumi Minamimoto
ResearchOpen Access03 Sept 2024
Communications Biology

Volume: 7, P: 1-11
Monoclonal antibody for phosphorylated TRIO Y2681 that helps predict prognosis of post-operative colorectal cancer patients

Taro Aoyama
Fumihiko Kakizaki
Makoto Mark Taketo
ResearchOpen Access25 Jul 2025
BJC Reports

Volume: 3, P: 1-8
A Kpna1-deficient psychotropic drug-induced schizophrenia model mouse for studying gene–environment interactions

Hirotaka Nomiya
Koki Sakurai
Masami Yamada
ResearchOpen Access09 Feb 2024
Scientific Reports

Volume: 14, P: 1-18
Analysis of the cells isolated from epithelial cell rests of Malassez through single-cell limiting dilution

Syed Taufiqul Islam
Yoshihito Kurashige
Masato Saitoh
ResearchOpen Access10 Jan 2022
Scientific Reports

Volume: 12, P: 1-15
A multiethnic meta-analysis defined the association of rs12946942 with severe adolescent idiopathic scoliosis

Kazuki Takeda
Ikuyo Kou
Shiro Ikegawa
Research21 Feb 2019
Journal of Human Genetics

Volume: 64, P: 493-498
Novel mutations in the SIL1 gene in a Japanese pedigree with the Marinesco–Sjögren syndrome

Taichi Takahata
Koki Yamada
Takashi Kitaoka
Research29 Jan 2010
Journal of Human Genetics

Volume: 55, P: 142-146
Predictors of early remission of proteinuria in adult patients with minimal change disease: a retrospective cohort study

Ryohei Yamamoto
Enyu Imai
Hiroyuki Komatsu
ResearchOpen Access13 Jun 2022
Scientific Reports

Volume: 12, P: 1-12
C-X-C domain ligand 14-mediated stromal cell–macrophage interaction as a therapeutic target for hand dermal fibrosis

Wnt/β-catenin signalling activation in the dermis cause fibrosis by cell-autonomous program and by a non-cell-autonomous program mediated by TGF-β niche formation based on Cxcl14-mediated interactions between stromal cells and M2 macrophages.

Atsushi Goto
Shingo Komura
Haruhiko Akiyama
ResearchOpen Access18 Nov 2023
Communications Biology

Volume: 6, P: 1-16
Upregulation of OASIS/CREB3L1 in podocytes contributes to the disturbance of kidney homeostasis

Upregulation of transcription factor OASIS in podocytes contributes to podocyte and/or tubular injury through decreased PRKCi expression and is a critical event for the disturbance of kidney homeostasis.

Yoshiaki Miyake
Masanori Obana
Yasushi Fujio
ResearchOpen Access22 Jul 2022
Communications Biology

Volume: 5, P: 1-14
Resistance to chemical carcinogenesis induction via a dampened inflammatory response in naked mole-rats

Naked mole rats are found to be resistant to cancer development through dampened inflammatory response due to genetically determined impaired necroptosis, with essential necroptosis genes RIPK3 and MLKL containing mutations causing premature stop codons.

Kaori Oka
Shusuke Fujioka
Kyoko Miura
ResearchOpen Access30 Mar 2022
Communications Biology

Volume: 5, P: 1-13
Experience-dependent learning of behavioral laterality in the scale-eating cichlid Perissodus microlepis occurs during the early developmental stage

Yuichi Takeuchi
Yuna Higuchi
Yoichi Oda
ResearchOpen Access14 Jan 2022
Scientific Reports

Volume: 12, P: 1-12
Determination of quasi-primary odors by endpoint detection

Hanxiao Xu
Koki Kitai
Ryo Tamura
ResearchOpen Access08 Jun 2021
Scientific Reports

Volume: 11, P: 1-12
Electrophysiological measurement of ion channels on plasma/organelle membranes using an on-chip lipid bilayer system

Koki Kamiya
Toshihisa Osaki
Shoji Takeuchi
ResearchOpen Access30 Nov 2018
Scientific Reports

Volume: 8, P: 1-9
A multi-ethnic meta-analysis confirms the association of rs6570507 with adolescent idiopathic scoliosis

Ikuyo Kou
Kota Watanabe
Shiro Ikegawa
ResearchOpen Access01 Aug 2018
Scientific Reports

Volume: 8, P: 1-8
An international meta-analysis confirms the association of BNC2 with adolescent idiopathic scoliosis

Yoji Ogura
Kazuki Takeda
Shiro Ikegawa
ResearchOpen Access16 Mar 2018
Scientific Reports

Volume: 8, P: 1-7
Epigenetic status and aberrant expression of the maspin gene in human hepato-biliary tract carcinomas

Kentaro Fujisawa
Chihaya Maesawa
Tomoyuki Masuda
Research20 Dec 2004
Laboratory Investigation

Volume: 85, P: 214-224

Search

Non-visual photoreceptive brain specification in sea urchin larvae

A leukaemic cell mutant with a thermolabile alanyl-transfer RNA synthetase

Associations of neuromelanin in the substantia nigra with antipsychotic response in schizophrenia

TRBC1-CAR T cell therapy in peripheral T cell lymphoma: a phase 1/2 trial

The DNA replication machinery transmits dual signals to prevent unscheduled licensing and execution of centrosome duplication

CAR T or NK cells targeting mismatched HLA-DR molecules in acute myeloid leukemia after allogeneic hematopoietic stem cell transplant

Immediate effect of physical activity on gut motility in healthy adults

PI3K-Akt signalling regulates Scx-lineage tenocytes and Tppp3-lineage paratenon sheath cells in neonatal tendon regeneration

Azilsartan causes natriuresis due to its sympatholytic action in kidney disease

Genome-wide association study identifies 14 previously unreported susceptibility loci for adolescent idiopathic scoliosis in Japanese

Safety and efficacy of laparoscopic repeat liver resection and re-operation for liver tumor

Sox2 is associated with cancer stem-like properties in colorectal cancer

The Cep57-pericentrin module organizes PCM expansion and centriole engagement

Cep295 is a conserved scaffold protein required for generation of a bona fide mother centriole

Association between amorphous calcium-phosphate ratios in circulating calciprotein particles and prognostic biomarkers in hemodialysis patients

TRPV2 is critical for the maintenance of cardiac structure and function in mice

Harnessing an integrated glyco-nanovaccine technology for enhanced cancer immunotherapy

Unsupervised decomposition of natural monkey behavior into a sequence of motion motifs

Monoclonal antibody for phosphorylated TRIO Y2681 that helps predict prognosis of post-operative colorectal cancer patients

A Kpna1-deficient psychotropic drug-induced schizophrenia model mouse for studying gene–environment interactions

Analysis of the cells isolated from epithelial cell rests of Malassez through single-cell limiting dilution

A multiethnic meta-analysis defined the association of rs12946942 with severe adolescent idiopathic scoliosis

Novel mutations in the SIL1 gene in a Japanese pedigree with the Marinesco–Sjögren syndrome

Predictors of early remission of proteinuria in adult patients with minimal change disease: a retrospective cohort study

C-X-C domain ligand 14-mediated stromal cell–macrophage interaction as a therapeutic target for hand dermal fibrosis

Upregulation of OASIS/CREB3L1 in podocytes contributes to the disturbance of kidney homeostasis

Resistance to chemical carcinogenesis induction via a dampened inflammatory response in naked mole-rats

Experience-dependent learning of behavioral laterality in the scale-eating cichlid Perissodus microlepis occurs during the early developmental stage

Determination of quasi-primary odors by endpoint detection

Electrophysiological measurement of ion channels on plasma/organelle membranes using an on-chip lipid bilayer system

A multi-ethnic meta-analysis confirms the association of rs6570507 with adolescent idiopathic scoliosis

An international meta-analysis confirms the association of BNC2 with adolescent idiopathic scoliosis

Epigenetic status and aberrant expression of the maspin gene in human hepato-biliary tract carcinomas

Search

Quick links

Search

Filter By:

Search

Quick links