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Showing 301–350 of 395 results

Advanced filters: Author: Kyle Jackson Clear advanced filters

convertibleCARs: A chimeric antigen receptor system for flexible control of activity and antigen targeting

Landgraf et al. developed a chimeric antigen receptor (CAR) platform that functions as a modular system. convertible^TM-T cells are designed to kill antigen-expressing target cells only in the presence of ligands fused to antigen-targeting antibodies (MicAbody^TM). This method provides a wide dosing window while minimizing toxicity.

Kyle E. Landgraf
Steven R. Williams
Kaman Chan Kim
ResearchOpen Access09 Jun 2020
Communications Biology

Volume: 3, P: 1-13
Fire effects on the persistence of soil organic matter and long-term carbon storage

Fires reduce plant biomass, which should deplete soil carbon stocks, but a review of recent literature shows that fires also slow decomposition rates and increase soil organic matter stability, offsetting aboveground biomass carbon losses.

Adam F. A. Pellegrini
Jennifer Harden
Robert B. Jackson
Reviews23 Dec 2021
Nature Geoscience

Volume: 15, P: 5-13
In situ imaging reveals disparity between prostaglandin localization and abundance of prostaglandin synthases

Duncan et al. use a mass spectrometry imaging method to assess the localization and concentration of prostaglandins (PGs) in mouse tissues during pregnancy. This study brings new biological insights into the spatial evaluation of PGs in tissues, which could reveal the functional significance of each PGs during different stages of embryo development/pregnancy.

Kyle D. Duncan
Xiaofei Sun
Ingela Lanekoff
ResearchOpen Access13 Aug 2021
Communications Biology

Volume: 4, P: 1-9
Deciphering the impact of genomic variation on function

The Impact of Genomic Variation on Function Consortium is combining single-cell mapping, genomic perturbations and predictive modelling to investigate relationships between human genomic variation, genome function and phenotypes and will provide an open resource to the community.

Jesse M. Engreitz
Heather A. Lawson
Ella K. Samer
Reviews04 Sept 2024
Nature

Volume: 633, P: 47-57
Blocking antibodies against integrin-α3, -αM, and -αMβ2 de-differentiate myofibroblasts, and improve lung fibrosis and kidney fibrosis

Michael J. V. White
Melis Ozkan
Jeffrey A. Hubbell
ResearchOpen Access16 Sept 2024
Scientific Reports

Volume: 14, P: 1-19
Helminth-induced Ly6C^hi monocyte-derived alternatively activated macrophages suppress experimental autoimmune encephalomyelitis

Cesar Terrazas
Juan de Dios Ruiz-Rosado
Santiago Partida-Sánchez
ResearchOpen Access17 Jan 2017
Scientific Reports

Volume: 7, P: 1-13
Mechanosensitive Kinases Regulate Stiffness-Induced Cardiomyocyte Maturation

Jennifer L. Young
Kyle Kretchmer
Adam J. Engler
ResearchOpen Access19 Sept 2014
Scientific Reports

Volume: 4, P: 1-11
Myosin-II mediated traction forces evoke localized Piezo1-dependent Ca²⁺ flickers

Ellefsen et al. monitor Piezo-dependent Calcium signals in live cells by TIRF and super-resolution microscopy and find that Ca²⁺ flickers localize to areas of high traction force. They show that Myosin II activity and MLCK are needed for the generation of Piezo Ca²⁺ signals and that Piezo1 channels are mobile in the plasma membrane.

Kyle L. Ellefsen
Jesse R. Holt
Medha M. Pathak
ResearchOpen Access07 Aug 2019
Communications Biology

Volume: 2, P: 1-13
FGF21 signaling in glutamatergic neurons is required for weight loss associated with dietary protein dilution

Kyle H. Flippo
Sharon O. Jensen-Cody
Matthew J. Potthoff
ResearchOpen Access11 Nov 2020
Scientific Reports

Volume: 10, P: 1-12
Vaccination with Mincle agonist UM-1098 and mycobacterial antigens induces protective Th1 and Th17 responses

Viktoria Rungelrath
Mushtaq Ahmed
Jay T. Evans
ResearchOpen Access06 Jun 2024
npj Vaccines

Volume: 9, P: 1-15
A Mal functional variant is associated with protection against invasive pneumococcal disease, bacteremia, malaria and tuberculosis

Chiea C Khor
Stephen J Chapman
Adrian V S Hill
Research25 Feb 2007
Nature Genetics

Volume: 39, P: 523-528
Mechanisms of osteopontin-stabilized amorphous calcium phosphate calcification in benign and pre-malignant breast disease

Mayandi Sivaguru
Sarah E. Schrup
Bruce W. Fouke
ResearchOpen Access04 Jul 2025
Scientific Reports

Volume: 15, P: 1-22
UV LED disinfection as a novel treatment for common salmonid pathogens

Kyle D. Rauch
Jessica L. Bennett
Graham A. Gagnon
ResearchOpen Access18 Nov 2024
Scientific Reports

Volume: 14, P: 1-8
Author Correction: Advances and prospects for the Human BioMolecular Atlas Program (HuBMAP)

Sanjay Jain
Liming Pei
Michael P. Snyder
Amendments and Corrections01 Mar 2024
Nature Cell Biology

Volume: 26, P: 839
Publisher Correction: Situational factors shape moral judgements in the trolley dilemma in Eastern, Southern and Western countries in a culturally diverse sample

Bence Bago
Marton Kovacs
Balazs Aczel
Amendments and Corrections06 Jun 2022
Nature Human Behaviour

Volume: 6, P: 897-898
Dietary polyphenols drive dose-dependent behavioral and molecular alterations to repeated morphine

Aya Osman
Rebecca S. Hofford
Drew D. Kiraly
ResearchOpen Access27 Jul 2023
Scientific Reports

Volume: 13, P: 1-13
A Single Dose of Modified Vaccinia Ankara expressing Ebola Virus Like Particles Protects Nonhuman Primates from Lethal Ebola Virus Challenge

Arban Domi
Friederike Feldmann
Andrea Marzi
ResearchOpen Access16 Jan 2018
Scientific Reports

Volume: 8, P: 1-9
Using ammonia as a shipping fuel could disturb the nitrogen cycle

Ammonia has been proposed as a shipping fuel, yet potential adverse side-effects are poorly understood. We argue that if nitrogen releases from ammonia are not tightly controlled, the scale of the demands of maritime transport are such that the global nitrogen cycle could be substantially altered.

Paul Wolfram
Page Kyle
Steven Smith
Comments & Opinion05 Oct 2022
Nature Energy

Volume: 7, P: 1112-1114
Cholinergic control of Th17 cell pathogenicity in experimental autoimmune encephalomyelitis

Robert Nechanitzky
Duygu Nechanitzky
Tak W. Mak
Research17 Dec 2022
Cell Death & Differentiation

Volume: 30, P: 407-416
Regional infusion of a class C TLR9 agonist enhances liver tumor microenvironment reprogramming and MDSC reduction to improve responsiveness to systemic checkpoint inhibition

Chandra C. Ghosh
Kara R. Heatherton
Steven C. Katz
ResearchOpen Access14 Jun 2022
Cancer Gene Therapy

Volume: 29, P: 1854-1865
Anxiolytic effects of NLRP3 inflammasome inhibition in a model of chronic sleep deprivation

Chad Smith
Kyle J. Trageser
Giulio Maria Pasinetti
ResearchOpen Access14 Jan 2021
Translational Psychiatry

Volume: 11, P: 1-15
Gasdermin D restricts Burkholderia cenocepacia infection in vitro and in vivo

Shady Estfanous
Kathrin Krause
Amal O. Amer
ResearchOpen Access13 Jan 2021
Scientific Reports

Volume: 11, P: 1-20
AAV1.NT-3 gene therapy for X-linked Charcot–Marie–Tooth neuropathy type 1

Burcak Ozes
Morgan Myers
Zarife Sahenk
ResearchOpen Access04 Feb 2021
Gene Therapy

Volume: 29, P: 127-137
Cellphone enabled point-of-care assessment of breast tumor cytology and molecular HER2 expression from fine-needle aspirates

Daniel Y. Joh
Jacob T. Heggestad
Ashutosh Chilkoti
ResearchOpen Access02 Jul 2021
npj Breast Cancer

Volume: 7, P: 1-14
Albino mice with the point mutation at the tyrosinase locus show high cholesterol diet-induced NASH susceptibility

Kaushalya Kulathunga
Arata Wakimoto
Michito Hamada
ResearchOpen Access08 Nov 2021
Scientific Reports

Volume: 11, P: 1-11
Expression of CCL2/CCR2 signaling proteins in breast carcinoma cells is associated with invasive progression

Wei Bin Fang
Diana Sofia Acevedo
Nikki Cheng
ResearchOpen Access22 Apr 2021
Scientific Reports

Volume: 11, P: 1-12
Predicting cancer drug TARGETS - TreAtment Response Generalized Elastic-neT Signatures

Nicholas R. Rydzewski
Erik Peterson
Shuang G. Zhao
ResearchOpen Access21 Sept 2021
npj Genomic Medicine

Volume: 6, P: 1-9
Biologically informed deep neural networks provide quantitative assessment of intratumoral heterogeneity in post treatment glioblastoma

Hairong Wang
Michael G. Argenziano
Jing Li
ResearchOpen Access19 Oct 2024
npj Digital Medicine

Volume: 7, P: 1-14
Mixed and membrane-separated culturing of synthetic cyanobacteria-yeast consortia reveals metabolic cross-talk mimicking natural cyanolichens

Pavlo Bohutskyi
Kyle R. Pomraning
Jon K Magnuson
ResearchOpen Access25 Oct 2024
Scientific Reports

Volume: 14, P: 1-19
A comparison of sexing methods in fetal mice

Scott Deeney
Kyle N. Powers
Timothy M. Crombleholme
Research21 Sept 2016
Lab Animal

Volume: 45, P: 380-384
Lipocalin 2 Does Not Play A Role in Celastrol-Mediated Reduction in Food Intake and Body Weight

Xudong Feng
Dongxian Guan
Umut Ozcan
ResearchOpen Access05 Sept 2019
Scientific Reports

Volume: 9, P: 1-12
Prophylactic effect of flavanol rich preparation metabolites in promoting resilience to a mouse model of social stress

Jun Wang
Danyue Zhao
Giulio M. Pasinetti
ResearchOpen Access09 Jun 2020
Translational Psychiatry

Volume: 10, P: 1-11
Genome-Wide Transcriptome Landscape of Embryonic Brain-Derived Neural Stem Cells Exposed to Alcohol with Strain-Specific Cross-Examination in BL6 and CD1 Mice

Wayne Xu
Vichithra R. B. Liyanage
Mojgan Rastegar
ResearchOpen Access18 Jan 2019
Scientific Reports

Volume: 9, P: 1-17
Assessment of Corneal Stromal Remodeling and Regeneration after Photorefractive Keratectomy

Pouriska B. Kivanany
Kyle C. Grose
W. Matthew Petroll
ResearchOpen Access22 Aug 2018
Scientific Reports

Volume: 8, P: 1-14
Depletion of dietary aryl hydrocarbon receptor ligands alters microbiota composition and function

Kyle M. Brawner
Venkata A. Yeramilli
Colin A. Martin
ResearchOpen Access11 Oct 2019
Scientific Reports

Volume: 9, P: 1-12
Contribution of D1R-expressing neurons of the dorsal dentate gyrus and Ca_v1.2 channels in extinction of cocaine conditioned place preference

Caitlin E. Burgdorf
Charlotte C. Bavley
Anjali M. Rajadhyaksha
Research06 Jan 2020
Neuropsychopharmacology

Volume: 45, P: 1506-1517
Upregulation of 5′-terminal oligopyrimidine mRNA translation upon loss of the ARF tumor suppressor

Kyle A. Cottrell
Ryan C. Chiou
Jason D. Weber
ResearchOpen Access17 Dec 2020
Scientific Reports

Volume: 10, P: 1-13
Nr2e3 is a genetic modifier that rescues retinal degeneration and promotes homeostasis in multiple models of retinitis pigmentosa

Sujun Li
Shyamtanu Datta
Neena B. Haider
ResearchOpen Access02 Mar 2020
Gene Therapy

Volume: 28, P: 223-241
Serum-circulating His-tRNA synthetase inhibits organ-targeted immune responses

Ryan A. Adams
Cátia Fernandes-Cerqueira
Paul Schimmel
ResearchOpen Access04 Dec 2019
Cellular & Molecular Immunology

Volume: 18, P: 1463-1475
Rapid sea level rise causes loss of seagrass meadows

A 23% decrease of seagrass in the western Gulf of Mexico over a five-year period, including the local decline of two seagrass species, was likely due to insufficient light availability from rapid sea level rise, according to long term survey and field monitoring programs.

Kyle A. Capistrant-Fossa
Kenneth H. Dunton
ResearchOpen Access19 Feb 2024
Communications Earth & Environment

Volume: 5, P: 1-9
Impact of chemokine C–C ligand 27, foreskin anatomy and sexually transmitted infections on HIV-1 target cell availability in adolescent South African males

Clive M. Gray
Kyle L. O’Hagan
Thomas J. Hope
ResearchOpen Access16 Oct 2019
Mucosal Immunology

Volume: 13, P: 118-127
Adipose Tissue Mast Cells Promote Human Adipose Beiging in Response to Cold

Brian S. Finlin
Amy L. Confides
Philip A. Kern
ResearchOpen Access17 Jun 2019
Scientific Reports

Volume: 9, P: 1-10
Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

Jason Flannick
Christian Fuchsberger
Mark I. McCarthy
ResearchOpen Access19 Dec 2017
Scientific Data

Volume: 4, P: 1-22
Relationships of PGRN with sTREM2 in AD continuum and non-AD pathophysiology and their reciprocal roles in modulating amyloid pathology: two population-based study

Liang-Yu Huang
Chen-Chen Tan
Dariella Fernandez
ResearchOpen Access08 Jul 2025
Translational Psychiatry

Volume: 15, P: 1-11
High-throughput fabrication of antimicrobial phage microgels and example applications in food decontamination

The authors describe how to prepare antimicrobial phage-based microgels, using polystyrene film templates, and detail their use to kill antibiotic-resistant bacteria in food contamination tests as an example application.

Lei Tian
Kyle Jackson
Zeinab Hosseinidoust
Protocols27 Feb 2024
Nature Protocols

Volume: 19, P: 1591-1622
BIRDBASE: A Global Dataset of Avian Biogeography, Conservation, Ecology and Life History Traits

Çağan H. Şekercioğlu
Kyle D. Kittelberger
Montague H. C. Neate-Clegg
ResearchOpen Access30 Sept 2025
Scientific Data

Volume: 12, P: 1-9
Caspase-11 and caspase-1 differentially modulate actin polymerization via RhoA and Slingshot proteins to promote bacterial clearance

Kyle Caution
Mikhail A. Gavrilin
Amal O. Amer
ResearchOpen Access21 Dec 2015
Scientific Reports

Volume: 5, P: 1-13
An Integrative Platform for Three-dimensional Quantitative Analysis of Spatially Heterogeneous Metastasis Landscapes

Ian H. Guldner
Lin Yang
Siyuan Zhang
ResearchOpen Access12 Apr 2016
Scientific Reports

Volume: 6, P: 1-13
DDX3Y gene rescue of a Y chromosome AZFa deletion restores germ cell formation and transcriptional programs

Cyril Ramathal
Benjamin Angulo
Renee Reijo Pera
ResearchOpen Access12 Oct 2015
Scientific Reports

Volume: 5, P: 1-13
Myocardin regulates mitochondrial calcium homeostasis and prevents permeability transition

Wajihah Mughal
Matthew Martens
Joseph W. Gordon
ResearchOpen Access06 Mar 2018
Cell Death & Differentiation

Volume: 25, P: 1732-1748

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