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Showing 1–5 of 5 results
Advanced filters: Author: Liji Wu Clear advanced filters
  • In this Perspective, members of the Aging Biomarker Consortium outline the X-Age Project, an Aging Biomarker Consortium plan for building standardized aging clocks in China. The authors discuss the project roadmap and its aims of decoding aging heterogeneity, detecting accelerated aging early and evaluating geroprotective interventions.

    • Jiaming Li
    • Mengmeng Jiang
    • Guang-Hui Liu
    Reviews
    Nature Aging
    Volume: 5, P: 1669-1685
  • Rosacea is a common, multi-factorial chronic inflammatory skin disorder. Here authors provide evidence of genetic predisposition by whole genome sequencing and whole exome sequencing of samples from familial cases, and by recapitulating a recurrent mutation in the LRRC4 gene in a mouse model, they find that neuron-derived vasoactive intestinal peptide is an important pathogenic factor for neurogenic inflammation in rosacea.’

    • Zhili Deng
    • Mengting Chen
    • Ji Li
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-15
  • Rosacea is a common chronic inflammatory skin disorder mainly affecting the central face. Here, a single-cell atlas of facial skin from rosacea patients and healthy individuals reveals the molecular and cellular changes in skin-resident cell populations and identifies fibroblasts as a determinant in rosacea development.

    • Mengting Chen
    • Li Yang
    • Ji Li
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-16