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Oat consumption, particularly a short-term, high-dose oat diet, improves metabolic health in individuals with metabolic syndrome by increasing microbially produced phenolic metabolites, leading to lower blood cholesterol levels.

The study presents a recyclable polymer system that stores solar energy and releases it as hydrogen on demand, offering an efficient and sustainable route for renewable energy storage and fuel generation.

Eutectic aqueous–organic electrolytes enable highly reversible zinc–manganese batteries without acid addition. By regulating the water-bonding network, beneficial manganese oxide phases are deposited and stripped while gas formation is suppressed, achieving ultraextended cycling.

Directing group strategies for selective dearomatization of unactivated aromatic π-systems have remained elusive. Now a homogeneous ruthenium catalyst, aided by a removable directing group, enables the site-selective hydrogenation of less reactive arene moieties in polyaryl compounds.

Borsa et al. show that asymmetric T cell division after activation requires autophagy to promote mitochondrial turnover, with T cells inheriting older mitochondria showing decreased degradation, reduced memory potential and altered metabolism.

Candida albicans must adapt to hypoxia. Here, the authors discover the sterol C4-methyl oxidase (SMO) Erg251 is essential for extreme hypoxic growth, as well as virulence and colonization, and that SMO inhibitors have therapeutic potential.

Severe summer aridification caused freshwater scarcity and the decline of Homo floresiensis and its prey at Liang Bua 61,000 years ago, as revealed by a rainfall record based on speleothem geochemical data from the island of Flores, Indonesia.

In a clinical trial in pregnant women with gestational diabetes, a dietary intervention for energy restriction was safe and did not result in any difference in maternal weight or offspring standardized birth weight outcomes compared to the control arm.

Subtle changes in solvent composition control peptide crystal polymorphism, enabling the formation of distinct structures and offering new insights for designing advanced bio-inspired materials.

Producing methanol — useful as both a fuel and a synthetic building block — from carbon monoxide and carbon dioxide has been achieved using homogeneous catalytic hydrogenation of carbonates, carbamates and formates. The catalyst is a dearomatized ruthenium(II) pincer complex and the reaction proceeds efficiently under mild conditions.

A 165 Myr record of N and Corg isotopes show that the N-cycle responds to feedbacks associated with productivity and the location of upwelling centers changing due to continental meander.

This analysis of whole-genome sequencing data from 421 multiple myeloma samples elucidates the timing of key genomic events and shows associations between the timing of 1q gain and clinical outcome.

Both click chemistry and polymer synthesis require reliable transformations with high selectivity, efficiency and fidelity. Now, bifluoride salts can be used as powerful catalysts for the sufur(VI) fluoride exchange (SuFEx) click reaction and they are applied to the synthesis of polysulfates and polysulfonates in a practical and scalable manner.

An extreme Einstein ring ~10,000 times as bright as the Milky Way in the infrared is studied with VLT/ERIS and ALMA, and the authors find that the lensed galaxy is a starburst with a fast-rotating disk, rather than being driven by a major merger.

Gas adsorption in porous materials offers an alternative technology for efficient hydrogen isotope separation. Here, the authors report high separation efficiency through isotopologue-induced structural dynamics in a readily scalable manganese-triazole metal-organic framework.

An analysis of the effect of mesophyll diffusion on the dynamics of the uptake of carbonyl sulfide by plants estimates global contemporary gross primary productivity to be 157 (±8.5) petagrams of carbon per year.

Better understanding of the chemistry of rechargeable metal–oxygen batteries is needed to fulfil their potential. It is now shown that proton phase-transfer catalysts drive Na–O₂ batteries, transporting superoxide between the electrode surface and the electrolyte as HO₂. The chemistry uncovered gives rise to the system's high reversible capacity.

Olefin metathesis is a powerful synthetic method that largely rests on the reactivity of molybdenum- and ruthenium-based catalysts, as alternative metals have not yet been successfully substituted. Here the authors engineer an iron catalyst to effectively perform the stereoselective ring-opening metathesis polymerization of norbornene.

Anisotropic superstructures produced by the self-assembly of spherical nanoparticles are realized. Uniformly grafting polymer chains onto inorganic spherical nanoparticles produces particles with amphiphile-like behaviour. Mixing these with monodisperse polymer facilitates the self-assembly of numerous anisotropic nanocomposites.

Conventional chemical engineering has limitations on heat transfer, leading to large setups. Here, authors propose a distributed electrified heating method, realizing fast and uniform heating of gaseous reactants, promising an energy-concentrated and compact reactor design.

The function of DNMT1 (DNA methyltransferase 1) in these subsets of immature, migrating cortical inhibitory interneurons is not fully understood. This study shows that DNMT1 regulates cortical development by orchestrating the migration of postmitotic SST+ interneurons and their signaling to cortical progenitors, with implications for proper cortical architecture and function.

Chemical disequilibrium is a known biosignature, and it is important to determine the conditions for its remote detection. A thermodynamical model coupled with atmospheric retrieval shows that a disequilibrium can be inferred for a Proterozoic Earth-like exoplanet in reflected light at a high O₂/CH₄ abundance case and signal-to-noise ratio of 50.

Time-resolved serial femtosecond crystallography is used to reveal the structural changes that stabilize the charge-separation steps of electron-transfer reactions in the photosynthetic reaction centre of Blastochloris viridis on a timescale of picoseconds.

An aluminium–chalcogen battery operating with a molten-salt electrolyte composed of NaCl–KCl–AlCl₃ is presented, which allows rapid charging at up to 200C for hundreds of cycles, and is scalable, fire-resistant and low cost.

Designing catalysts with atomically synergistic sites shows great promise as a pathway for advanced catalyst development. Here the authors report Zn-Cr catalyst with atomically binuclear active sites for iso-stoichiometric co-conversion of ethane and CO₂ through proximal atomic synergy.

Nitroxyl radicals have many important applications but are generally stabilized through steric bulk on the adjacent carbon centres. Here, the authors design a simple, modular preparation of nitroxyl radicals with α-hydrogens that are stable for extended periods and are catalytically active.

Simple enzyme mimetics are highly desired for industrial settings providing high catalyst stability and low production costs. This work reports that phenylalanine and zinc ions can self-assemble into a supramolecular structure showing catalytic properties similar to those of the natural enzyme carbonic anhydrase.

In the context of enviromental applications, refining enzymes into more minimalist structures could ease production costs, improve stability, and improve reusability. Here, the authors report a single amino acid bionanozyme that can catalyze the rapid oxidation of environmentally toxic phenolic contaminates and serves as a tool to detect biologically important neurotransmitters similar to the laccase enzyme.