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Showing 1–50 of 63 results

Advanced filters: Author: Liwen He Clear advanced filters

Bioremediation of complex organic pollutants by engineered Vibrio natriegens

A synthetic biology approach was used to engineer Vibrio natriegens into a strain capable of bioremediating complex organic pollutants in saline wastewater and soils, thereby addressing notable threats to marine biosecurity.

Cong Su
Haotian Cui
Hongzhi Tang
Research07 May 2025
Nature

Volume: 642, P: 1024-1033
TRIP13 promotes the expansion and immunosuppression of CD4⁺Foxp3⁺ regulatory T cells by sustaining HAT1 stability

Tianzhen He
Liwen Zhao
Yong-Jing Gao
ResearchOpen Access14 Jan 2026
Cell Death & Disease

Volume: 17, P: 1-15
ENO1-mediated deoxycytidine synthesis and gemcitabine resistance by stabilizing RRM2 in pancreatic cancer

Yongning Li
Hao Wang
Chao Yu
ResearchOpen Access27 Dec 2025
Cell Death & Disease

Volume: 17, P: 1-14
Underwater soft arm grasping with simplified control using octopus-inspired bending propagation

Jiaqi Liu
Zhichao Zhu
Li Wen
ResearchOpen Access07 Jan 2026
npj Robotics

Volume: 4, P: 1-13
mRNA-LNP vaccine encoding CDV hemagglutinin confers effective protection in raccoon dogs

Chengqi Zhang
Tiyun Han
Xue Bai
ResearchOpen Access14 Dec 2025
npj Vaccines

Volume: 11, P: 1-14
Functional optic tract rewiring via subtype- and target-specific axonal regeneration and presynaptic activity enhancement

CNS injuries cause persistent deficits. Here, the authors show that regenerated axons in an optic tract injury model form functional synapses, restoring the pupillary light reflex, and highlight neuronal types and presynaptic activity in recovery.

Xin Zhang
Chao Yang
Kai Liu
ResearchOpen Access04 Mar 2025
Nature Communications

Volume: 16, P: 1-20
A programmable platelet theranostic platform for adaptive multi-stage delivery and synergistic immunotherapy in atherosclerosis

Macrophages play essential roles in the progression and rupture of atherosclerosis. Here, the authors report an adaptable platelet-protein platform tailored for the targeted delivery of both antioxidant nanocatalysts and TRAF6 inhibitor to advance synergistic therapy for atherosclerosis.

Yi Li
Xueping Li
Wen Li
ResearchOpen Access11 Jul 2025
Nature Communications

Volume: 16, P: 1-22
Sexual dimorphism of lung immune-regulatory units imprint biased pulmonary fibrosis

Peng Xiang
Liwen Wang
Hai-Yan Zhou
Research14 May 2025
Cellular & Molecular Immunology

Volume: 22, P: 743-759
Disrupting the phase separation of KAT8–IRF1 diminishes PD-L1 expression and promotes antitumor immunity

Wu et al. report that IFNγ induces the phase separation of KAT8 and IRF1 into condensates that promote PD-L1 upregulation. They further identify a peptide that blocks KAT8–IRF1 condensates, reducing PD-L1 levels and increasing antitumor immunity.

Yuanzhong Wu
Liwen Zhou
Tiebang Kang
ResearchOpen Access09 Mar 2023
Nature Cancer

Volume: 4, P: 382-400
The utilization of cytology for intraoperative diagnosis of primary central nervous system lymphoma

Liwen Hu
Jianqing Tang
Xingfu Wang
ResearchOpen Access03 Nov 2024
Scientific Reports

Volume: 14, P: 1-8
MicroRNA expression in peripheral blood of children with asthma and the role of miR-31-5p in childhood asthma progression

Wenwei Luo
Gang Li
Zhengrong Chen
ResearchOpen Access31 Oct 2025
Scientific Reports

Volume: 15, P: 1-15
Spontaneous dynamical disordering of borophenes in MgB₂ and related metal borides

Layered boron compounds attract enormous interest in applications. This work reports first-principles calculations coupled with global optimization to show that the outer boron surface in MgB₂ nanosheets undergo disordering and clustering, which is experimentally confirmed in synthesized MgB₂ nanosheets.

Sichi Li
Harini Gunda
Brandon C. Wood
ResearchOpen Access01 Nov 2021
Nature Communications

Volume: 12, P: 1-12
Joint analysis of phenotype-effect-generation identifies loci associated with grain quality traits in rice hybrids

Genetic dissection of hybrids is more difficult than inbreds as nonadditive effects are involved. Here, the authors report a pipeline for joint analysis of phenotypes, effects, and generations and demonstrate its usefulness in identification of loci associated with quality traits and improving predict accuracy in genomic selection of hybrid rice.

Lanzhi Li
Xingfei Zheng
Zhongli Hu
ResearchOpen Access04 Jul 2023
Nature Communications

Volume: 14, P: 1-9
The plant unique ESCRT component FREE1 regulates autophagosome closure

Nutrient sensing impinges on the autophagosome biogenesis. Here, the authors present evidence that plant energy sensing regulates the autophagosome closure by modulating the phosphorylation status and localization of the ESCRT machinery.

Yonglun Zeng
Baiying Li
Liwen Jiang
ResearchOpen Access30 Mar 2023
Nature Communications

Volume: 14, P: 1-17
Senescent immune cells accumulation promotes brown adipose tissue dysfunction during aging

With increasing age, brown adipose tissue (BAT) becomes characterized by increased adiposity and immune cell infiltration but reduced thermogenic capacity. Here the authors report that bone marrow-derived pro-inflammatory and senescent S100A8⁺ immune cells accumulate in BAT of male rats and mice during aging and contribute to BAT dysfunction.

Xu Feng
Liwen Wang
Haiyan Zhou
ResearchOpen Access02 Jun 2023
Nature Communications

Volume: 14, P: 1-17
TAGAP instructs Th17 differentiation by bridging Dectin activation to EPHB2 signaling in innate antifungal response

TAGAP gene variants are linked to human autoimmunity. Here the authors identify TAGAP as a Dectin-1 and EphB2-binding protein mediating antifungal innate immune signaling and cytokine production, and demonstrate TAGAP in non-T cells promotes Th17 response in mouse models of infection and autoimmunity.

Jianwen Chen
Ruirui He
Chenhui Wang
ResearchOpen Access20 Apr 2020
Nature Communications

Volume: 11, P: 1-16
A whole-cell electron tomography model of vacuole biogenesis in Arabidopsis root cells

The plant vacuole plays important roles in regulating growth and development. Now, the vacuole in Arabidopsis root cells is presented at nanometre resolution by 3D whole-cell tomography, suggesting a cellular mechanism for plant vacuole formation.

Yong Cui
Wenhan Cao
Liwen Jiang
Research17 Dec 2018
Nature Plants

Volume: 5, P: 95-105
Identification of microbial markers across populations in early detection of colorectal cancer

The gut microbiome plays an important role in colorectal carcinogenesis and predictive microbiome signatures have been proposed for colorectal cancer (CRC) diagnosis. Here the authors perform a meta-analysis of 16S rRNA-based profiles to identify microbial markers able to discriminate patients with adenoma from control and CRC, building a model that can be applied for the early detection of CRC.

Yuanqi Wu
Na Jiao
Lixin Zhu
ResearchOpen Access24 May 2021
Nature Communications

Volume: 12, P: 1-13
Deep learning radiomics based prediction of axillary lymph node metastasis in breast cancer

Han Liu
Liwen Zou
Wentao Kong
ResearchOpen Access12 Mar 2024
npj Breast Cancer

Volume: 10, P: 1-9
Bacteria hijack a meningeal neuroimmune axis to facilitate brain invasion

Two Streptococcus spp. can utilize a neuropeptide (CGRP) and its receptor (RAMP1) on macrophages to promote brain invasion, a finding that may help the development of therapies for bacterial meningitis.

Felipe A. Pinho-Ribeiro
Liwen Deng
Isaac M. Chiu
Research01 Mar 2023
Nature

Volume: 615, P: 472-481
NO at low concentration can enhance the formation of highly oxygenated biogenic molecules in the atmosphere

Nitrogen monoxide at low concentrations can promote the formation of highly oxygenated organic molecules, which are crucial precursors to secondary organic aerosol (SOA), rather than inhibit it as traditionally thought.

Wei Nie
Chao Yan
Aijun Ding
ResearchOpen Access08 Jun 2023
Nature Communications

Volume: 14, P: 1-11
Preservation of microvascular barrier function requires CD31 receptor-induced metabolic reprogramming

The mechanisms that restore endothelial barrier integrity following inflammation-induced breaching are incompletely understood. Here the authors show that the CD31 immune receptor contributes to reestablishing vascular integrity via its effects on endothelial cell metabolism.

Kenneth C. P. Cheung
Silvia Fanti
Federica M. Marelli-Berg
ResearchOpen Access17 Jul 2020
Nature Communications

Volume: 11, P: 1-18
Dynamic alterations of oral fungal microbiota in Omicron infected patients

Yarong Ma
Shanshuo Liu
Zhigang Ren
ResearchOpen Access14 Oct 2025
Scientific Reports

Volume: 15, P: 1-13
Cooperative insertion of CO₂ in diamine-appended metal-organic frameworks

A cooperative insertion mechanism for CO₂ adsorption is shown to generate highly efficient adsorbents for carbon capture applications.

Thomas M. McDonald
Jarad A. Mason
Jeffrey R. Long
Research11 Mar 2015
Nature

Volume: 519, P: 303-308
FAM83B inhibits ovarian cancer cisplatin resistance through inhibiting Wnt pathway

Shanyang He
Wei Wang
Liwen Zhu
ResearchOpen Access09 Jan 2021
Oncogenesis

Volume: 10, P: 1-10
Cooperative adsorption of carbon disulfide in diamine-appended metal–organic frameworks

The large-scale production of CS₂ presents both environmental and biological hazards, yet adsorbents capable of CS₂ capture remain scarcely explored. Here, Long and colleagues demonstrate that CS₂ is adsorbed in diamine-appended metal–organic frameworks through a cooperative and chemically specific insertion process.

C. Michael McGuirk
Rebecca L. Siegelman
Jeffrey R. Long
ResearchOpen Access03 Dec 2018
Nature Communications

Volume: 9, P: 1-10
Translocation of vaginal microbiota is involved in impairment and protection of uterine health

Here, the authors present a comparative analyses on vaginal and uterine microbiota in 1223 samples derived from 655 women with chronic endometritis, which, combined with animal experiments, characterize the microbial translocation in the female reproductive tract and its role in modulating uterine health.

Jinfeng Wang
Zhanzhan Li
Fangqing Zhao
ResearchOpen Access07 Jul 2021
Nature Communications

Volume: 12, P: 1-15
Influence of prefabricated fissure angles on mechanical and infrared properties of red sandstone and failure prediction based on deep learning

Liwen He
Xin Xue
Dongping Shi
ResearchOpen Access08 Oct 2025
Scientific Reports

Volume: 15, P: 1-19
Coinhibition of the MEK/RTK pathway has high therapeutic efficacy in KRAS-mutant non-small cell lung cancer

Jun Lu
Minjuan Hu
Baohui Han
ResearchOpen Access12 Sept 2025
Signal Transduction and Targeted Therapy

Volume: 10, P: 1-18
A new cathode material for super-valent battery based on aluminium ion intercalation and deintercalation

Wei Wang
Bo Jiang
Shuqiang Jiao
ResearchOpen Access29 Nov 2013
Scientific Reports

Volume: 3, P: 1-6
Analyzing the CDR3 Repertoire with respect to TCR—Beta Chain V-D-J and V-J Rearrangements in Peripheral T Cells using HTS

Long Ma
Liwen Yang
Xinsheng Yao
ResearchOpen Access12 Jul 2016
Scientific Reports

Volume: 6, P: 1-10
CASPR2 antibody associated neurological syndromes in children

Liwen Wu
Fang Cai
Zhenghui Xiao
ResearchOpen Access06 Feb 2023
Scientific Reports

Volume: 13, P: 1-13
A novel mutation of DNA2 regulates neuronal cell membrane potential and epileptogenesis

Yuting Liu
Haiyan Yang
Liwen Wu
ResearchOpen Access27 May 2024
Cell Death Discovery

Volume: 10, P: 1-12
NSUN2 stimulates tumor progression via enhancing TIAM2 mRNA stability in pancreatic cancer

Guizhen Zhang
Liwen Liu
Guangying Cui
ResearchOpen Access01 Jul 2023
Cell Death Discovery

Volume: 9, P: 1-14
A novel recessive TTN founder variant is a common cause of distal myopathy in the Serbian population

Stojan Perić
Jelena Nikodinović Glumac
Volker Straub
Research15 Mar 2017
European Journal of Human Genetics

Volume: 25, P: 572-581
Analysis of clinical phenotypic and genotypic spectra in 36 children patients with Epilepsy of Infancy with Migrating Focal Seizures

Haiyan Yang
Xiaofan Yang
Liwen Wu
ResearchOpen Access17 Jun 2022
Scientific Reports

Volume: 12, P: 1-10
Cinnamaldehyde accelerates wound healing by promoting angiogenesis via up-regulation of PI3K and MAPK signaling pathways

Xing Yuan
Lin Han
Runhui Liu
Research20 Feb 2018
Laboratory Investigation

Volume: 98, P: 783-798
Altered mitochondrial DNA copy number contributes to human cancer risk: evidence from an updated meta-analysis

Liwen Hu
Xinyue Yao
Yi Shen
ResearchOpen Access24 Oct 2016
Scientific Reports

Volume: 6, P: 1-11
Transient expression and analysis of fluorescent reporter proteins in plant pollen tubes

Hao Wang
Liwen Jiang
Protocols10 Mar 2011
Nature Protocols

Volume: 6, P: 419-426
CAVD, towards better characterization of void space for ionic transport analysis

Bing He
Anjiang Ye
Siqi Shi
ResearchOpen Access22 May 2020
Scientific Data

Volume: 7, P: 1-13
NEDD4-2 and the CLC-2 channel regulate neuronal excitability in the pathogenesis of mesial temporal lobe epilepsy

Yuting Liu
Haiyan Yang
Liwen Wu
ResearchOpen Access28 Feb 2024
Scientific Reports

Volume: 14, P: 1-10
An intersegmental single-cell profile reveals aortic heterogeneity and identifies a novel Malat1⁺ vascular smooth muscle subtype involved in abdominal aortic aneurysm formation

Liwen Yu
Jie Zhang
Cheng Zhang
ResearchOpen Access27 Apr 2022
Signal Transduction and Targeted Therapy

Volume: 7, P: 1-14
Long-term exposure to high particulate matter pollution and incident hypertension: a 12-year cohort study in northern China

Chaokang Li
Yaoyan Li
Nai-jun Tang
Research18 Jan 2021
Journal of Human Hypertension

Volume: 35, P: 1129-1138
Improved maximum likelihood method for P-S-N curve fitting method with small number specimens and application in T-welded joint

Wenfei Liu
Li Zhang
Hailang Liu
ResearchOpen Access06 Nov 2023
Scientific Reports

Volume: 13, P: 1-14
A novel missense variant in ACAA1 contributes to early-onset Alzheimer’s disease, impairs lysosomal function, and facilitates amyloid-β pathology and cognitive decline

Rongcan Luo
Yu Fan
Yong-Gang Yao
ResearchOpen Access31 Aug 2021
Signal Transduction and Targeted Therapy

Volume: 6, P: 1-16
Correction: SMARCC2 mediates the regulation of DKK1 by the transcription factor EGR1 through chromatin remodeling to reduce the proliferative capacity of glioblastoma

Chiyang Li
Tong Wang
Qiang Zhou
Amendments and CorrectionsOpen Access12 Dec 2022
Cell Death & Disease

Volume: 13, P: 1
C/EBPα deficiency in podocytes aggravates podocyte senescence and kidney injury in aging mice

Liwen Zhang
Fangfang Zhou
Nan Chen
ResearchOpen Access17 Sept 2019
Cell Death & Disease

Volume: 10, P: 1-15
Correction: FAM83B inhibits ovarian cancer cisplatin resistance through inhibiting Wnt pathway

Shanyang He
Wei Wang
Liwen Zhu
Amendments and CorrectionsOpen Access15 Mar 2023
Oncogenesis

Volume: 12, P: 1-3
Correction to: FAM83B inhibits ovarian cancer cisplatin resistance through inhibiting Wnt pathway

Shanyang He
Wei Wang
Liwen Zhu
Amendments and CorrectionsOpen Access10 Feb 2021
Oncogenesis

Volume: 10, P: 1
SMARCC2 mediates the regulation of DKK1 by the transcription factor EGR1 through chromatin remodeling to reduce the proliferative capacity of glioblastoma

Chiyang Li
Tong Wang
Qiang Zhou
ResearchOpen Access23 Nov 2022
Cell Death & Disease

Volume: 13, P: 1-14

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