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Showing 1–7 of 7 results
Advanced filters: Author: Lucie Liger Clear advanced filters

  • Cell-type deconvolution methods are often needed to analyse spatial transcriptomic data to recover cell-type distributions. In this Review, the authors describe the process of cell-type deconvolution, contrast the tools available and highlight important considerations for which tool to use.

    • Lucie C. Gaspard-Boulinc
    • Luca Gortana
    • Florence M. G. Cavalli
    Reviews
    Nature Reviews Genetics
    Volume: 26, P: 828-846

  • An analysis of 24,202 critical cases of COVID-19 identifies potentially druggable targets in inflammatory signalling (JAK1), monocyte–macrophage activation and endothelial permeability (PDE4A), immunometabolism (SLC2A5 and AK5), and host factors required for viral entry and replication (TMPRSS2 and RAB2A).

    • Erola Pairo-Castineira
    • Konrad Rawlik
    • J. Kenneth Baillie
    ResearchOpen Access
    Nature
    Volume: 617, P: 764-768

  • Prolonged snow cover in the southwestern Alps delayed ecosystem development until the 1980s, with current incipient soils and sparse vegetation reflecting a lagged response to recent warming rather than equilibrium with present conditions, as revealed by reconstructing fine-scale snow cover changes over the past 250 years.

    • Philippe Choler
    • Nicolas Bonfanti
    • Jérôme Poulenard
    ResearchOpen Access
    Communications Earth & Environment
    Volume: 6, P: 1-9

  • An overview of methods that can be used in high and maximum containment to study virus–host interactions in the infection microenvironment.

    • Emily Speranza
    Reviews
    Nature Microbiology
    Volume: 8, P: 1397-1407