Nature Search

Catalytically competent nickel(I)–isocyanide compounds for cross-coupling reactions

Nickel-catalysed cross-coupling reactions generally use Ni(II) or Ni(0) precatalysts. Here the authors report thermally stable dinuclear Ni(I) complexes with commercial isocyanide ligands for the efficient catalysis in Kumada, Suzuki–Miyaura and Buchwald–Hartwig cross-coupling reactions.

Sagnik Chakrabarti
Ju Byeong Chae
Liviu M. Mirica
Research14 Jan 2026
Nature Catalysis

P: 1-12
Measurement of correlated charge noise in superconducting qubits at an underground facility

Ionizing radiation can cause simultaneous charge noise in multi-qubit superconducting devices. Here, the authors measure space- and time-correlated charge jumps in a four-qubit system in a low-radiation underground facility, achieving operation with minimal correlated events over 22 h at qubit separations beyond 3 mm.

G. Bratrud
S. Lewis
D. Bowring
ResearchOpen Access11 Nov 2025
Nature Communications

Volume: 16, P: 1-5
Accumulation of Trehalose 6-Phosphate in Candidozyma auris results in Decreased Echinocandin Resistance and Tolerance

Echinocandins are the first-line therapy for invasive Candidozyma auris infections, but the resistance to this drug is increasing. Here, the authors identify a potential target with a distinct mechanism of action for improving echinocandin treatment in C. auris.

Qingjuan Zhu
Sien Van de Velde
Patrick Van Dijck
ResearchOpen Access13 Dec 2025
Nature Communications

Volume: 17, P: 1-19
Evolutionary loss of an antibiotic efflux pump increases Pseudomonas aeruginosa quorum sensing mediated virulence in vivo

Antibiotics and nutritional stresses can inactivate Pseudomonas aeruginosa efflux pump mexEFoprN. Here, the authors demonstrate that the inactivation of this efflux pump impacts quorum sensing mediated virulence in P. aeruginosa clinical isolates.

Sheryl E. Fernandes
Humberto Ortega
Peter Jorth
ResearchOpen Access25 Sept 2025
Nature Communications

Volume: 16, P: 1-15
Heterogeneity of H Chains of Myeloma Proteins : Susceptibility to Papain and Trypsin

M. D. POULIK
J. SHUSTER
Research07 Nov 1964
Nature

Volume: 204, P: 577-579
Determination of the spin and parity of all-charm tetraquarks

The CMS Collaboration reports the measurement of the spin, parity, and charge conjugation properties of all-charm tetraquarks, exotic fleeting particles formed in proton–proton collisions at the Large Hadron Collider.

A. Hayrapetyan
V. Makarenko
A. Snigirev
ResearchOpen Access03 Dec 2025
Nature

Volume: 648, P: 58-63
Genomic and microenvironmental heterogeneity shaping epithelial-to-mesenchymal trajectories in cancer

The intermediate states of the epithelial-to-mesenchymal transition (EMT) in cancer require further molecular characterisation. Here, the authors develop a method to evaluate EMT transformation and trajectories in cancer transcriptomics data, characterising EMT macro-states, including a hybrid state, and EMT hallmarks.

Guidantonio Malagoli Tagliazucchi
Anna J. Wiecek
Maria Secrier
ResearchOpen Access11 Feb 2023
Nature Communications

Volume: 14, P: 1-20
Influenza vaccines promote humoral and cellular immune responses: a randomized, double-blind, phase 3 trial

The authors report a trial subset analysis of the immune responses induced by two inactivated quadrivalent influenza vaccines (QIVs): Sinovac QIV and Vaxigrip-Tetra™. Both vaccines elicit robust humoral responses and distinct T cell profiles.

Linmar Rodríguez-Guilarte
Constanza Méndez
Alexis M. Kalergis
ResearchOpen Access07 Dec 2025
Nature Communications

Volume: 17, P: 1-14
Exotic terranes of western California

M. O. McWilliams
D. G. Howell
Research20 May 1982
Nature

Volume: 297, P: 215-217
Eight millennia of continuity of a previously unknown lineage in Argentina

A previously unsampled deep lineage in central Argentina was discovered that had distinctive genetic drift by 8,500 bp and persisted as the main Native American ancestry component in the region up to the present day.

Javier Maravall-López
Josefina M. B. Motti
Rodrigo Nores
Research05 Nov 2025
Nature

Volume: 649, P: 647-656
Direct observations of the dopant environment in fluorites using EXAFS

C. R. A. Catlow
A. V. Chadwick
L. M. Moroney
Research13 Dec 1984
Nature

Volume: 312, P: 601-604
Variability, Structural Glycoproteins, and Classification of Herpes Simplex Viruses

BERNARD ROIZMAN
JOHN M. KELLER
WALTER DOWDLE
Research19 Sept 1970
Nature

Volume: 227, P: 1253-1254
Long-distance distribution of genuine energy-time entanglement

Practical implementations of quantum communication need to securely deliver information over long distances without line-of-sight. Towards this goal, Cuevas et al.use an actively stabilized interferometer to close the geometry loophole for a Bell inequality violation over 1 km of optical fibre.

A. Cuevas
G. Carvacho
G.B. Xavier
ResearchOpen Access29 Nov 2013
Nature Communications

Volume: 4, P: 1-6
Explainable artificial intelligence for predictive modeling of student stress in higher education

Rasikh Tariq
M. G. Orozco-del-Castillo
Tabbi Wilberforce
ResearchOpen Access03 Nov 2025
Scientific Reports

Volume: 15, P: 1-28
Targeted transcriptional downregulation of MYC using epigenomic controllers demonstrates antitumor activity in hepatocellular carcinoma models

Development of targeted MYC inhibitors for cancer therapy remains challenging. Here, the authors design an mRNA medicine which downregulates MYC gene transcription via epigenetic modification of MYC regulatory elements, showing significant antitumor activity in preclinical models of hepatocellular carcinoma.

William Senapedis
Kayleigh M. Gallagher
Thomas G. McCauley
ResearchOpen Access16 Sept 2024
Nature Communications

Volume: 15, P: 1-17
Impacts of detritivore diversity loss on instream decomposition are greatest in the tropics

It is unclear whether stream detritivore diversity enhances decomposition across climates. Here the authors manipulate litter diversity and examine detritivore assemblages in a globally distributed stream litterbag experiment, finding a positive diversity-decomposition relationship stronger in tropical streams, where detritivore diversity is lower.

Luz Boyero
Naiara López-Rojo
Catherine M. Yule
ResearchOpen Access17 Jun 2021
Nature Communications

Volume: 12, P: 1-11
Production of Specific Anti-E Autoantibodies in Experimental Iso-immune Hæmolytic Anæsmia in Man

JAMES F. MOHN
REGINALD M. LAMBERT
F. WELLS BRASON
Research17 Aug 1963
Nature

Volume: 199, P: 705-706
TCF1 and LEF1 promote B-1a cell homeostasis and regulatory function

The transcription factors TCF1 and LEF1 promote self-renewal and regulatory functions in B-1a cells.

Qian Shen
Hao Wang
Carola G. Vinuesa
ResearchOpen Access20 Aug 2025
Nature

Volume: 646, P: 442-451
Analysis of more than 400,000 women provides case-control evidence for BRCA1 and BRCA2 variant classification

BRCA1 and BRCA2 are well known breast cancer predisposition genes, however, many variants have not yet been classified for their pathogenicity. Here, the authors analyse a large combined cohort to provide evidence of variant pathogenicity.

Maria Zanti
Denise G. O’Mahony
Kyriaki Michailidou
ResearchOpen Access25 May 2025
Nature Communications

Volume: 16, P: 1-18
Genes required for GABA function in Caenorhabditis elegans

Steven L. Mclntire
Erik Jorgensen
H. Robert Horvitz
Research22 Jul 1993
Nature

Volume: 364, P: 334-337
Emergence of the Ug99 lineage of the wheat stem rust pathogen through somatic hybridisation

Strain Ug99 of the wheat stem rust pathogen, Puccinia graminis f. sp. tritici, is a major threat to global food security. Here, the authors present genomic analyses supporting that Ug99 arose as a result of non-sexual genetic exchange between dikaryotic ancestors.

Feng Li
Narayana M. Upadhyaya
Melania Figueroa
ResearchOpen Access07 Nov 2019
Nature Communications

Volume: 10, P: 1-15
Comparative socioeconomic, environmental and technical analysis of conventional versus smart sustainable integrated multi-trophic aquaponics systems

Ashraf M. A.-S. Goda
Eman Y. Mohammady
Ehab El-Haroun
ResearchOpen Access11 Nov 2025
Scientific Reports

Volume: 15, P: 1-24
Single-cell and spatial transcriptomic profiling of cardiac fibroblasts following myocardial infarction

Silvia C. Hernández
Marina Ainciburu
David Gómez-Cabrero
ResearchOpen Access13 Jan 2026
Scientific Data

P: 1-14
Neoadjuvant anti-PD1 immunotherapy for surgically accessible recurrent glioblastoma: clinical and molecular outcomes of a stage 2 single-arm expansion cohort

Glioblastoma is resistant to immune-checkpoint inhibitors. In this study, the authors report the results of an expansion cohort (n = 25) of a randomized testing neoadjuvant plus adjuvant pembrolizumab versus adjuvant pembrolizumab alone in patients with recurrent glioblastoma with resectable tumors.

J. Ricardo McFaline-Figueroa
Lu Sun
Patrick Y. Wen
ResearchOpen Access30 Dec 2024
Nature Communications

Volume: 15, P: 1-9
Collection of Lymph from Kidneys Homotransplanted in Man: Cell Transformation in vivo

J. HAMBURGER
A. DIMITRIU
J. AUVERT
Research27 Aug 1971
Nature

Volume: 232, P: 633-634
Chromosomes of Cancer Cells

J. A. KIRKLAND
M. A. STANLEY
Research27 Aug 1971
Nature

Volume: 232, P: 632-633
Evidence for the Existence of Two Corticotrophin-releasing Factors, α and β

A. V. SCHALLY
R. N. ANDERSEN
ROGER GUILLEMIN
Research31 Dec 1960
Nature

Volume: 188, P: 1192-1193
Renal Proliferation in the Unilaterally Nephrectomized Rat

DAVID M. KESSNER
E. DONNALL THOMAS
Research08 Apr 1961
Nature

Volume: 190, P: 175-176
Activation of a Qa/Tla class I major histocompatibility antigen gene is a general feature of oncogenesis in the mouse

Paul M. Brickell
David S. Latchman
Peter W. J. Rigby
Research22 Dec 1983
Nature

Volume: 306, P: 756-760
Common West African HLA antigens are associated with protection from severe malaria

Adrian V. S. Hill
Catherine E. M. Allsopp
Brian M. Greenwood
Research15 Aug 1991
Nature

Volume: 352, P: 595-600
A new H–2-linked class I gene whose expression depends on a maternally inherited factor

Kirsten Fischer Lindahl
Barbara Hausmann
Verne M. Chapman
Research24 Nov 1983
Nature

Volume: 306, P: 383-385
Whole-brain annotation and multi-connectome cell typing of Drosophila

A consensus cell type atlas for the fly brain provides both an intellectual framework and open-source toolchains for brain-scale comparative connectomics.

Philipp Schlegel
Yijie Yin
Gregory S. X. E. Jefferis
ResearchOpen Access02 Oct 2024
Nature

Volume: 634, P: 139-152
A Late Devonian actinopterygian suggests high lineage survivorship across the end-Devonian mass extinction

An actinopterygian fossil with unexpected anatomical features from 7 million years before the end-Devonian mass extinction suggests complex patterns of divergence and diversification around the Devonian/Carboniferous boundary for ray-finned fishes.

Sam Giles
Kara Feilich
Matt Friedman
Research17 Nov 2022
Nature Ecology & Evolution

Volume: 7, P: 10-19
Functional EGF receptors are present on mouse embryo tissues

Eileen D. Adamson
M. Jane Deller
Joseph B. Warshaw
Research25 Jun 1981
Nature

Volume: 291, P: 656-659
Genome-wide association study of long COVID

A genome-wide study by the Long COVID Host Genetics Initiative identifies an association between the FOXP4 locus and long COVID, implicating altered lung function in its pathophysiology.

Vilma Lammi
Tomoko Nakanishi
Hanna M. Ollila
ResearchOpen Access21 May 2025
Nature Genetics

Volume: 57, P: 1402-1417
Identification of a modulator of the actin cytoskeleton, mitochondria, nutrient metabolism and lifespan in yeast

Actin cables affect lifespan by supporting movement and inheritance of fitter mitochondria to daughter cells in yeast. Here the authors show that branched-chain amino acid (BCAA) levels affect actin cable stability and a role for YKL075C/AAN1 in control of BCAA metabolism and actin cable stability and function.

Cierra N. Sing
Enrique J. Garcia
Liza A. Pon
ResearchOpen Access16 May 2022
Nature Communications

Volume: 13, P: 1-12
Apparent Size of Holes felt with the Tongue

S. M. ANSTIS
Research01 Aug 1964
Nature

Volume: 203, P: 792-793
Body temperature changes during the practice of g Tum-mo yoga

JAY M. PASACHOFF
Research22 Jul 1982
Nature

Volume: 298, P: 402
Conserved chromatin and repetitive patterns reveal slow genome evolution in frogs

Frogs are an ancient and ecologically diverse group of amphibians that include important model systems. This paper reports genome sequences of multiple frog species, revealing remarkable stability of frog chromosomes and centromeres, along with highly recombinogenic extended subtelomeres.

Jessen V. Bredeson
Austin B. Mudd
Daniel S. Rokhsar
ResearchOpen Access17 Jan 2024
Nature Communications

Volume: 15, P: 1-18
A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci

Montserrat Garcia-Closas and colleagues report a genome-wide association study for bladder cancer. They identify three new susceptibility loci on chromosomes 22q13.1, 19q12 and 2q37.1.

Nathaniel Rothman
Montserrat Garcia-Closas
Stephen J Chanock
Research24 Oct 2010
Nature Genetics

Volume: 42, P: 978-984
Convective cloud merging and its effect on rainfall

D. A. Bennetts
M. J. Bader
R. H. Marles
Research04 Nov 1982
Nature

Volume: 300, P: 42-45
A multinational Delphi consensus to end the COVID-19 public health threat

A diverse, multidisciplinary panel of 386 experts in COVID-19 response from 112 countries provides health and social policy actions to address inadequacies in the pandemic response and help to bring this public health threat to an end.

Jeffrey V. Lazarus
Diana Romero
Anne Øvrehus
ResearchOpen Access03 Nov 2022
Nature

Volume: 611, P: 332-345
Galectin-3/CD146 interaction promotes renal damage and systemic inflammation after acute kidney injury

L. Boutin
S. M. Figueroa
Christos E. Chadjichristos
ResearchOpen Access24 Nov 2025
Scientific Reports

Volume: 15, P: 1-15
An atomic switch realized with the scanning tunnelling microscope

D. M. Eigler
C. P. Lutz
W. E. Rudge
Research15 Aug 1991
Nature

Volume: 352, P: 600-603
Thixo-viscoelastoplastic rheological characterisation of human mucus using a multimode BMP constitutive equation approach

Michelle Figueroa-Landeta
Sarahí L. Esponda-Cervantes
J. Esteban López-Aguilar
ResearchOpen Access12 Dec 2025
Scientific Reports

Volume: 15, P: 1-27
Independent evolution of structural and coding regions in a Neurospora mitochondrial intron

Elizabeth M. Mota
Richard A. Collins
Research14 Apr 1988
Nature

Volume: 332, P: 654-656
Dysregulation of macrophage PEPD in obesity determines adipose tissue fibro-inflammation and insulin resistance

Obesity-associated AT fibro-inflammation and metabolic disturbances are linked to PEPD activity and PEPD extracellular levels.

V. Pellegrinelli
S. Rodriguez-Cuenca
A. Vidal-Puig
Research25 Apr 2022
Nature Metabolism

Volume: 4, P: 476-494
Effects of foetal haemoglobin on susceptibility of red cells to Plasmodium falciparum

G. PASVOL
D. J. WEATHERALL
R. J. M. WILSON
Research10 Nov 1977
Nature

Volume: 270, P: 171-173
A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer

A transcriptome-wide association study identifies associations of genetically predicted gene expression with breast cancer risk. This analysis finds 48 candidate genes implicated in breast cancer susceptibility, including 14 at novel loci.

Lang Wu
Wei Shi
Wei Zheng
Research18 Jun 2018
Nature Genetics

Volume: 50, P: 968-978
Modelling ciliopathy phenotypes in human tissues derived from pluripotent stem cells with genetically ablated cilia

Tissues and organoids derived from human pluripotent stem cells with knocked-out kinesin-2 subunits lack cilia, and can be used to model ciliopathy phenotypes and to reveal underlying mechanisms of disease.

Nelly M. Cruz
Raghava Reddy
Benjamin S. Freedman
Research27 Apr 2022
Nature Biomedical Engineering

Volume: 6, P: 463-475

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