Microbial colonization and biofilm formation drive persistent infections on medical devices, often under fluid flow. Here, the authors engineer buckling-induced wrinkled and folded patterns with precisely defined geometries, integrate them into microfluidic channels, and show how wrinkling instabilities can be exploited to mitigate bacterial colonization under dynamic conditions.
- Luca Pellegrino
- Giovanni Savorana
- Roberto Rusconi