It is shown that mice lacking the renal Rhcg factor have impaired ammonium excretion, thereby refuting the long-standing notion that rapid transepithelial transport of non-ionic ammonia occurs solely by lipid phase diffusion. In addition, it is shown that Rhcg is required for epididymal fluid homeostasis with clear consequences for male fertility.
- Sophie Biver
- Hendrica Belge
- Anna Maria Marini
